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Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease
Open accessAbstract
OBJECTIVE: To test the effectiveness of an integrated collaborative care model for people with depression and long term physical conditions. DESIGN: Cluster randomised controlled trial. SETTING: 36 general practices in the north west of England. PARTICIPANTS: 387 patients with a record of diabetes or heart disease, or both, who had depressive symptoms (≥ 10 on patient health questionaire-9 (PHQ-9)) for at least two weeks. Mean age was 58.5 (SD 11.7). Participants reported a mean of 6.2 (SD 3.0) long term conditions other than diabetes or heart disease; 240 (62%) were men; 360 (90%) completed the trial. INTERVENTIONS: Collaborative care included patient preference for behavioural activation, cognitive restructuring, graded exposure, and/or lifestyle advice, management of drug treatment, and prevention of relapse. Up to eight sessions of psychological treatment were delivered by specially trained psychological wellbeing practitioners employed by Improving Access to Psychological Therapy services in the English National Health Service; integration of care was enhanced by two treatment sessions delivered jointly with the practice nurse. Usual care was standard clinical practice provided by general practitioners and practice nurses. MAIN OUTCOME MEASURES: The primary outcome was reduction in symptoms of depression on the self reported symptom checklist-13 depression scale (SCL-D13) at four months after baseline assessment. Secondary outcomes included anxiety symptoms (generalised anxiety disorder 7), self management (health education impact questionnaire), disability (Sheehan disability scale), and global quality of life (WHOQOL-BREF). RESULTS: 19 general practices were randomised to collaborative care and 20 to usual care; three practices withdrew from the trial before patients were recruited. 191 patients were recruited from practices allocated to collaborative care, and 196 from practices allocated to usual care. After adjustment for baseline depression score, mean depressive scores were 0.23 SCL-D13 points lower (95% confidence interval -0.41 to -0.05) in the collaborative care arm, equal to an adjusted standardised effect size of 0.30. Patients in the intervention arm also reported being better self managers, rated their care as more patient centred, and were more satisfied with their care. There were no significant differences between groups in quality of life, disease specific quality of life, self efficacy, disability, and social support. CONCLUSIONS: Collaborative care that incorporates brief low intensity psychological therapy delivered in partnership with practice nurses in primary care can reduce depression and improve self management of chronic disease in people with mental and physical multimorbidity. The size of the treatment effects were modest and were less than the prespecified effect but were achieved in a trial run in routine settings with a deprived population with high levels of mental and physical multimorbidity. TRIAL REGISTRATION: ISRCTN80309252.
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“Studies of treatment interventions using standard CBT protocols for depression and/ or anxiety in LTCs report low levels of engagement with these interventions (Ciechanowski et al . 2010; Coventry et al . 2015).”
From Improving Distress in Dialysis (iDiD): A tailored CBT self-management treatment for patients undergoing dialysis. (2016) · cites this paper as Coventry et al . 2015
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“These problems are diminishing, thanks to concerted efforts across a number of countries to regulate trial registration and reporting. 582”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [582]
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Cites
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765
Multiple imputation using chained equations: Issues and guidance for practice
White, I. R., Royston, P., & Wood, A. M. (2011) · Statistics in Medicine · doi:10.1002/sim.4067 · Cited by 9,792
Barnett, K., Mercer, S. W., Norbury, M., Watt, G., Wyke, S., & Guthrie, B. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60240-2 · Cited by 6,972
Skevington, S. M., Lotfy, M., & O'Connell, K. A. (2004) · Quality of Life Research · doi:10.1023/b:qure.0000018486.91360.00 · Cited by 4,686
Depression, chronic diseases, and decrements in health: results from the World Health Surveys
Moussavi, S., Chatterji, S., Verdes, E., Tandon, A., Patel, V., & Ustun, B. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61415-9 · Cited by 4,070
No health without mental health
Prince, M. J., Patel, V., Saxena, S., Maj, M., Maselko, J., Phillips, M. R., & Rahman, A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61238-0 · Cited by 4,028
Consort 2010 statement: extension to cluster randomised trials
Campbell, M. K., Piaggio, G., Elbourne, D. R., Altman, D. G., & for the CONSORT Group (2012) · BMJ · doi:10.1136/bmj.e5661 · Cited by 3,510
A Note on Robust Variance Estimation for Cluster‐Correlated Data
Williams, R. L. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00645.x · Cited by 2,501
Unützer, J., Katon, W., Callahan, C. M., Williams, Jr., Hunkeler, E., Harpole, L., Hoffing, M., Della Penna, R. D., Noël, P. H., Lin, E. H. B., et al. (2002) · JAMA · doi:10.1001/jama.288.22.2836 · Cited by 2,405
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3 of the 69 references couldn’t be matched to a known paper.
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- [23]NICE. Depression. The treatment and management of depression in adults (updated edition). NICE Clinical Guidelines, No 90. British Psychological Society, 2010. 22132433
- [26]Derogatis LR, Cleary PA. Confirmation of the dimensional structure of the scl-90: a study in construct validation. J Clin Psychol 1977; 33: 981-89.
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Sorted by citations
Items 301–323 of 323
van Zanten, R., van Dijk, M., van Rosmalen, J., Beck, D. K., Zietse, R., Van Hecke, A., van Staa, A., & Massey, E. K. (2022) · Figshare · doi:10.6084/m9.figshare.17981951
Sullivan, M. K., Jani, B. D., McConnachie, A., Hanlon, P., McLoone, P., Nicholl, B. I., Carrero, J.-J., Nitsch, D., McAllister, D., Mair, F. S., et al. (2021) · Figshare · doi:10.6084/m9.figshare.17047034
van Zanten, R., van Dijk, M., van Rosmalen, J., Beck, D. K., Zietse, R., Van Hecke, A., van Staa, A., & Massey, E. K. (2022) · Figshare · doi:10.6084/m9.figshare.17981948
Langton, J. M., Wong, S. T., Burge, F., Choi, A., Ghaseminejad-Tafreshi, N., Johnston, S., Katz, A., Lavergne, R., Mooney, D., Peterson, S., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12402449
Langton, J. M., Wong, S. T., Burge, F., Choi, A., Ghaseminejad-Tafreshi, N., Johnston, S., Katz, A., Lavergne, R., Mooney, D., Peterson, S., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12402458
Li, M., Tang, H., & Liu, X. (2024) · Figshare · doi:10.6084/m9.figshare.26562586
Langton, J. M., Wong, S. T., Burge, F., Choi, A., Ghaseminejad-Tafreshi, N., Johnston, S., Katz, A., Lavergne, R., Mooney, D., Peterson, S., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12402467
Li, M., Tang, H., & Liu, X. (2024) · Figshare · doi:10.6084/m9.figshare.26562583
Li, M., Tang, H., & Liu, X. (2024) · Figshare · doi:10.6084/m9.figshare.26562580
Sawrikar, V., & Nicklas, L. (2026) · British Journal of Clinical Psychology · doi:10.1111/bjc.70024
Patient-Centred Care for Multimorbid Patients: A Scoping Review
den Wyngaert, I. V., Vaes, B., Delvaux, N., & Pottelbergh, G. V. (2026) · Journal of Clinical Medicine · doi:10.3390/jcm15103774
“The intervention was not led by a physician in all studies but sometimes also by another https://doi.org/10.3390/jcm15103774 HCP or trained facilitator (Table S5) [44,45,47,48,51,53,54,56,57,62,64–66,73 ,75”
InfluentialChoudhary, S. K., Sharma, J., Sharma, R., Sharma, S., Saini, N., Rain, M., Dahiya, N., Singh, G., & Anand, A. (2026) · Journal of Ayurveda and Integrative Medicine · doi:10.1016/j.jaim.2026.101326
“A 12-week yoga program significantly reduced the levels of CRP and IL-6 in patients with depression and heart disease, according to another randomised controlled experiment conducted by Innes and colleagues (2015) [24].”
Junger, A. L., Fonseca, E. S., Sousa, A. L. L., & Batista, S. R. R. (2026) · BMJ Open · doi:10.1136/bmjopen-2026-117387
“22 23 27–30 Despite the findings, the literature remains fragmented regarding how illness perceptions interact with health behaviours in populations with multiple chronic conditions.”
Aggarwal, V. R., Witkowska, A., & Lovell, K. (2026) · Primary Dental Journal · doi:10.1177/20501684261441670
Self-citationCollaborative care treatment for major depressive disorder
Walker, C., Little, V., & Lyons, J. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1798572
Nawaz, S., Bee, P., & Faija, C. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-08135-5
“Better integrated pathways between TT and external providers are associated with more coordinated care and more efficient service use [66–68].”
Ajele, K. W., & Idemudia, E. S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-30263-3.00016-6
Recovery-focused approach in public mental health: barriers and recommendations
Roy, A., Philip, S., & Athili, A. (2026) · Journal of Public Mental Health · doi:10.1108/jpmh-04-2026-0091
Chopra, M., Rajkhowa, P., Ghosal, S., Ikhile, D., Rao, N., Gupta, M., Cassambai, S., Venkateshmurthy, N. S., Oli, N., Pachya, A. T., et al. (2026) · BMJ Public Health · doi:10.1136/bmjph-2025-004602
“16 23 These findings are consistent with previous literature reporting positive outcomes associated with CoCM implementation in MLTC care.”
Huang, J., Zhang, T., Yu, Y., 许秀峰, Wang, Z., Xu, Y., Li, T., Xu, G., Xu, X., Wang, L., et al. (2026) · Epidemiology and Psychiatric Sciences · doi:10.1017/s2045796026101036
“Interventions that address clusters of conditions, rather than isolated diagnoses, may more accurately target the sources of impaired perceived health (Coventry et al. , 2015).”
Remskar, M., Greaves, C. J., Chew-Graham, C., Stathi, A., Andersson, G., Kingstone, T., Hayhoe, S., & Lambert, J. D. (2026) · PLoS ONE · doi:10.1371/journal.pone.0355366
“[38,56,68], diabetes distress (4”
InfluentialSelf-citationBlinker, E. J., Amoh, G. K. A., Ankamah, S., Agyemang, C. O., Omech, B., Beune, E., Wekesah, F. M., Azumah, M., & Munneke, W. (2026) · BMJ Open · doi:10.1136/bmjopen-2026-125828
Ngalande, I., Chigere, A., Ng’ambi, W., & Zyambo, C. (2026) · Preventive Medicine Research & Reviews · doi:10.4103/pmrr.pmrr_56_26 · Cited by 2
Metadata
- Authors
- Coventry, P., Lovell, K., Dickens, C., Bower, P., Chew-Graham, C., McElvenny, D., Hann, M., Cherrington, A., Garrett, C., Gibbons, C. J., Baguley, C., Roughley, K., Adeyemi, I., Reeves, D., Waheed, W., & Gask, L.
- Affiliations
- Manchester Academic Health Science Centre (GB)
- University of Exeter (GB)
- National Institute for Health and Care Research (GB)
- Keele University (GB)
- Health Education North West (GB)
- University of Liverpool (GB)
- Lancashire Care NHS Foundation Trust (GB)
- Corresponding author
- Coventry, P.
- ORCID
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2015-02-16
- Volume
- 350
- Issue
- feb16 3
- Pages
- h638-h638
- ISSN
- 1756-1833 (ISSN-L)
- PMC
- PMC4353275
- OpenAlex
- W2112219174
- Cited by
- 325
- References
- 69
- Citations by year
- 2026: 19 · 2025: 22 · 2024: 30 · 2023: 13 · 2022: 27 · 2021: 28 · 2020: 39 · 2019: 31 · 2018: 35 · 2017: 25 · 2016: 37 · 2015: 19
- FWCI
- 63.27
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion, cc-by-nc)
- Figshare (submittedVersion)
- Open Research Exeter (University of Exeter) (submittedVersion, cc-by-nc)
- Funders
- National Institute for Health and Care Research
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- collaborative care, depression, multimorbidity, diabetes mellitus, cardiovascular disease, integrated primary care, behavioral activation, cognitive restructuring, graded exposure, practice nurses, self-management, quality of life, disability, relapse prevention, patient satisfaction, patient-centered care, general practice, anxiety symptoms, self-efficacy, social support
- MeSH terms
- Cardiovascular Diseases, Depression, Female, Humans, Male, Middle Aged, Patient Care Team, Primary Health Care, Cluster Analysis, Delivery of Health Care, Integrated, Diabetes Complications
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