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Integrated primary care for patients with mental and physical multimorbidity: cluster randomised controlled trial of collaborative care for patients with depression comorbid with diabetes or cardiovascular disease
Open accessAbstract
OBJECTIVE: To test the effectiveness of an integrated collaborative care model for people with depression and long term physical conditions. DESIGN: Cluster randomised controlled trial. SETTING: 36 general practices in the north west of England. PARTICIPANTS: 387 patients with a record of diabetes or heart disease, or both, who had depressive symptoms (≥ 10 on patient health questionaire-9 (PHQ-9)) for at least two weeks. Mean age was 58.5 (SD 11.7). Participants reported a mean of 6.2 (SD 3.0) long term conditions other than diabetes or heart disease; 240 (62%) were men; 360 (90%) completed the trial. INTERVENTIONS: Collaborative care included patient preference for behavioural activation, cognitive restructuring, graded exposure, and/or lifestyle advice, management of drug treatment, and prevention of relapse. Up to eight sessions of psychological treatment were delivered by specially trained psychological wellbeing practitioners employed by Improving Access to Psychological Therapy services in the English National Health Service; integration of care was enhanced by two treatment sessions delivered jointly with the practice nurse. Usual care was standard clinical practice provided by general practitioners and practice nurses. MAIN OUTCOME MEASURES: The primary outcome was reduction in symptoms of depression on the self reported symptom checklist-13 depression scale (SCL-D13) at four months after baseline assessment. Secondary outcomes included anxiety symptoms (generalised anxiety disorder 7), self management (health education impact questionnaire), disability (Sheehan disability scale), and global quality of life (WHOQOL-BREF). RESULTS: 19 general practices were randomised to collaborative care and 20 to usual care; three practices withdrew from the trial before patients were recruited. 191 patients were recruited from practices allocated to collaborative care, and 196 from practices allocated to usual care. After adjustment for baseline depression score, mean depressive scores were 0.23 SCL-D13 points lower (95% confidence interval -0.41 to -0.05) in the collaborative care arm, equal to an adjusted standardised effect size of 0.30. Patients in the intervention arm also reported being better self managers, rated their care as more patient centred, and were more satisfied with their care. There were no significant differences between groups in quality of life, disease specific quality of life, self efficacy, disability, and social support. CONCLUSIONS: Collaborative care that incorporates brief low intensity psychological therapy delivered in partnership with practice nurses in primary care can reduce depression and improve self management of chronic disease in people with mental and physical multimorbidity. The size of the treatment effects were modest and were less than the prespecified effect but were achieved in a trial run in routine settings with a deprived population with high levels of mental and physical multimorbidity. TRIAL REGISTRATION: ISRCTN80309252.
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“Studies of treatment interventions using standard CBT protocols for depression and/ or anxiety in LTCs report low levels of engagement with these interventions (Ciechanowski et al . 2010; Coventry et al . 2015).”
From Improving Distress in Dialysis (iDiD): A tailored CBT self-management treatment for patients undergoing dialysis. (2016) · cites this paper as Coventry et al . 2015
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“These problems are diminishing, thanks to concerted efforts across a number of countries to regulate trial registration and reporting. 582”
From Time for united action on depression: a Lancet–World Psychiatric Association Commission (2022) · cites this paper as [582]
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Cites
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765
Multiple imputation using chained equations: Issues and guidance for practice
White, I. R., Royston, P., & Wood, A. M. (2011) · Statistics in Medicine · doi:10.1002/sim.4067 · Cited by 9,792
Barnett, K., Mercer, S. W., Norbury, M., Watt, G., Wyke, S., & Guthrie, B. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60240-2 · Cited by 6,972
Skevington, S. M., Lotfy, M., & O'Connell, K. A. (2004) · Quality of Life Research · doi:10.1023/b:qure.0000018486.91360.00 · Cited by 4,686
Depression, chronic diseases, and decrements in health: results from the World Health Surveys
Moussavi, S., Chatterji, S., Verdes, E., Tandon, A., Patel, V., & Ustun, B. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61415-9 · Cited by 4,070
No health without mental health
Prince, M. J., Patel, V., Saxena, S., Maj, M., Maselko, J., Phillips, M. R., & Rahman, A. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61238-0 · Cited by 4,028
Consort 2010 statement: extension to cluster randomised trials
Campbell, M. K., Piaggio, G., Elbourne, D. R., Altman, D. G., & for the CONSORT Group (2012) · BMJ · doi:10.1136/bmj.e5661 · Cited by 3,510
A Note on Robust Variance Estimation for Cluster‐Correlated Data
Williams, R. L. (2000) · Biometrics · doi:10.1111/j.0006-341x.2000.00645.x · Cited by 2,501
Unützer, J., Katon, W., Callahan, C. M., Williams, Jr., Hunkeler, E., Harpole, L., Hoffing, M., Della Penna, R. D., Noël, P. H., Lin, E. H. B., et al. (2002) · JAMA · doi:10.1001/jama.288.22.2836 · Cited by 2,405
The client satisfaction questionnaire
Attkisson, C. C., & Zwick, R. (1982) · Evaluation and Program Planning · doi:10.1016/0149-7189(82)90074-x · Cited by 1,743
Collaborative care for patients with depression and chronic illnesses
Katon, W. J., Lin, E. H. B., Von Korff, M., Ciechanowski, P., Ludman, E. J., Young, B., Peterson, D., Rutter, C. M., McGregor, M., & McCulloch, D. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1003955 · Cited by 1,697
Sheehan, D. V., Harnett-Sheehan, K., & Raj, B. A. (1996) · International Clinical Psychopharmacology · doi:10.1097/00004850-199606003-00015 · Cited by 1,440
Spertus, J., Winder, J. A., Dewhurst, T. A., Deyo, R., Prodzinski, J., McDonnell, M., & Fihn, S. (1995) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)00397-9 · Cited by 1,413
Outcome Measures for Health Education and Other Health Care Interventions
Lorig, K., Stewart, A., Ritter, P., González, V., Laurent>, D., & Lynch, J. (1996) · doi:10.4135/9781452232966 · Cited by 1,132
Collaborative care for depression and anxiety problems
Archer, J., Bower, P., Gilbody, S., Lovell, K., Richards, D., Gask, L., Dickens, C., & Coventry, P. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006525.pub2 · Cited by 1,126
Self-citationDevelopment and Validation of the Patient Assessment of Chronic Illness Care (PACIC)
Glasgow, R. E., Wagner, E. H., Schaefer, J. K., Mahoney, L. D., Reid, R. J., & Greene, S. M. (2005) · Medical Care · doi:10.1097/01.mlr.0000160375.47920.8c · Cited by 875
Scale up services for mental disorders: a call for action
(2007) · The Lancet · doi:10.1016/s0140-6736(07)61242-2 · Cited by 835
Katon (2004) · doi:10.1001/archpsyc.61.10.1042 · Cited by 737
The English Indices of Deprivation 2010
McLennan, D., Barnes, H., Noble, M., Davies, J., Garrett, E., & Dibben, C. J. L. (2011) · Cited by 591
A Short Social Support Measure for Patients Recovering From Myocardial Infarction
Mitchell, P. H., Powell, L. H., Blumenthal, J. A., Norten, J., Ironson, G. H., Pitula, C. R., Froelicher, E. S., Czajkowski, S. M., Youngblood, M., Huber, M., et al. (2003) · Journal of Cardiopulmonary Rehabilitation · doi:10.1097/00008483-200311000-00001 · Cited by 577
Osborne, R. H., Elsworth, G. R., & Whitfield, K. (2007) · Patient Education and Counseling · doi:10.1016/j.pec.2006.12.002 · Cited by 556
Treatment allocation by minimisation
Altman, D. G., & Bland, J. M. (2005) · BMJ · doi:10.1136/bmj.330.7495.843 · Cited by 550
The DCCT Research Group (1988) · Diabetes Care · doi:10.2337/diacare.11.9.725 · Cited by 509
English Indices of Deprivation
Communities (2013) · Cited by 409
Credibility of claims of subgroup effects in randomised controlled trials: systematic review
Sun, X., Briel, M., Busse, J. W., You, J. J., Akl, E. A., Mejza, F., Bała, M. M., Bassler, D., Mertz, D., Diaz-Granados, N., et al. (2012) · BMJ · doi:10.1136/bmj.e1553 · Cited by 397
(2012) · Cited by 389
Multimorbidity: redesigning health care for people who use it
Salisbury, C. (2012) · The Lancet · doi:10.1016/s0140-6736(12)60482-6 · Cited by 326
Management of depression for people with cancer (SMaRT oncology 1): a randomised trial
Strong, V., Waters, R., Hibberd, C. J., Murray, G. D., Wall, L. R., Walker, J., McHugh, G. S., Walker, A., & Sharpe, M. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60991-5 · Cited by 324
Cape, J., Whittington, C., Buszewicz, M., Wallace, P., & Underwood, L. (2010) · BMC Medicine · doi:10.1186/1741-7015-8-38 · Cited by 283
Depression in adults with a chronic physical health problem: Treatment and management
Haddad, M. (2009) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2009.08.007 · Cited by 271
Collaborative Care for Patients with Depression and Chronic Illnesses
Jk, W., Ehb, L., Von Korff, M., Ciechanowski, P. S., Ej, L., Young, B. A., Peterson, D., Rutter, C. M., McGregor, M., & McCulloch, D. K. (2011) · Cited by 270
Sharpe, M., Walker, J., Hansen, C. H., Martin, P., Symeonides, S., Gourley, C., Wall, L., Weller, D., & Murray, G. (2014) · The Lancet · doi:10.1016/s0140-6736(14)61231-9 · Cited by 269
Facilitated physical activity as a treatment for depressed adults: randomised controlled trial
Chalder, M., Wiles, N., Campbell, J., Hollinghurst, S., Haase, A. M., Taylor, A. H., Fox, K. R., Costelloe, C., Searle, A., Baxter, H., et al. (2012) · BMJ · doi:10.1136/bmj.e2758 · Cited by 245
Depression as a Prognostic Factor for Breast Cancer Mortality
Hjerl, K., Andersen, E. W., Keiding, N., Mouridsen, H. T., Mortensen, P. B., & Jørgensen, T. (2003) · Psychosomatics · doi:10.1176/appi.psy.44.1.24 · Cited by 223
Coventry, P. A., Hudson, J. L., Kontopantelis, E., Archer, J., Richards, D. A., Gilbody, S., Lovell, K., Dickens, C., Gask, L., Waheed, W., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0108114 · Cited by 221
Self-citationGunn, J. M., Diggens, J., Hegarty, K. L., & Blashki, G. A. (2006) · BMC Health Services Research · doi:10.1186/1472-6963-6-88 · Cited by 219
Richards, D., Hill, J. J., Gask, L., Lovell, K., Chew-Graham, C., Bower, P., Cape, J., Pilling, S., Araya, R., Kessler, D., et al. (2013) · British medical journal · doi:10.1136/bmj.f4913 · Cited by 210
Self-citationScreening and case finding instruments for depression
Gilbody, S., House, A., & Sheldon, T. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002792.pub2 · Cited by 205
Bayliss, E. A., Ellis, J., & Steiner, J. F. (2008) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2008.05.002 · Cited by 169
Managing patients with mental and physical multimorbidity
Mercer, S. W., Gunn, J., Bower, P., Wyke, S., & Guthrie, B. (2012) · BMJ · doi:10.1136/bmj.e5559 · Cited by 159
Self-citationMental Health: Facing the Challenges, Building Solutions
Robinson, K. (2006) · International Journal of Migration Health and Social Care · doi:10.1108/17479894200600019 · Cited by 153
Morgan, M. A. J., Coates, M. J., Dunbar, J. A., Reddy, P., Schlicht, K., & Fuller, J. (2013) · BMJ Open · doi:10.1136/bmjopen-2012-002171 · Cited by 123
Multimorbidity and the inverse care law in primary care
Mercer, S. W., Guthrie, B., Furler, J., Watt, G. C. M., & Hart, J. T. (2012) · BMJ · doi:10.1136/bmj.e4152 · Cited by 117
Can Depression Treatment in Primary Care Reduce Disability?: A Stepped Care Approach
Lin, E. (2000) · Archives of Family Medicine · doi:10.1001/archfami.9.10.1052 · Cited by 110
Minimization–reducing predictability for multi-centre trials whilst retaining balance within centre
Brown, S., Thorpe, H., Hawkins, K., & Brown, J. (2005) · Statistics in Medicine · doi:10.1002/sim.2391 · Cited by 97
Development of a multimorbidity illness perceptions scale (MULTIPleS)
Gibbons, C. J., Kenning, C., Coventry, P. A., Bee, P., Bundy, C., Fisher, L., & Bower, P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081852 · Cited by 94
Korff, M. V., Katon, W. J., Lin, E. H. B., Ciechanowski, P. S., Peterson, D., Ludman, E. J., Young, B. A., & Rutter, C. M. (2011) · BMJ · doi:10.1136/bmj.d6612 · Cited by 87
Knowles, S. E., Chew-Graham, C. A., Coupe, N., Adeyemi, I., Keyworth, C., Thampy, H. K., & Coventry, P. A. (2013) · Implementation Science · doi:10.1186/1748-5908-8-110 · Cited by 84
Self-citationThe citation index: Another case of spurious validity
Thorne, F. C. (1977) · Journal of Clinical Psychology · doi:10.1002/1097-4679(197710)33:4 · Cited by 80
Outcome Measures for Health Education and Other Health Care Interventions
Scott, F. (1997) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/54.8.1002 · Cited by 74
Lovell, K., Bower, P., Richards, D., Barkham, M., Sibbald, B., Roberts, C., Davies, L., Rogers, A., Gellatly, J., & Hennessy, S. (2008) · BMC Psychiatry · doi:10.1186/1471-244x-8-91 · Cited by 73
Self-citationBallenger, J. C. (2006) · Yearbook of Psychiatry and Applied Mental Health · doi:10.1016/s0084-3970(08)70254-8 · Cited by 71
Rick, J., Rowe, K., Hann, M., Sibbald, B., Reeves, D., Roland, M. O., & Bower, P. (2012) · BMC Health Services Research · doi:10.1186/1472-6963-12-293 · Cited by 66
Self-citationDickens, C. M., Katon, W. J., Blakemore, A., Khara, A., McGowan, L., Tomenson, B., Jackson, J., Walker, L., & Guthrie, E. (2012) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2012.08.018 · Cited by 64
Self-citationDepression is a Risk Factor for Mortality in Coronary Heart Disease
Carney, R. M., Freedland, K. E., & Sheps, D. S. (2004) · Psychosomatic Medicine · doi:10.1097/01.psy.0000146795.38162.b1 · Cited by 48
Казаковцев, Б. А., Krasnov, V. N., Levina, N., & Nemtsov, A. V. (2005) · PubMed · Cited by 44
Quinsey, V. L., Harris, G. T., Rice, M. E., & Cormier, C. A. (1998) · American Psychological Association eBooks · doi:10.1037/10304-010 · Cited by 36
Baker, R., Robertson, N., Rogers, S., Davies, M. J., Brunskill, N. J., Khunti, K., STEINER, M. C., Williams, M., & Sinfield, P. (2009) · Implementation Science · doi:10.1186/1748-5908-4-72 · Cited by 34
Feeney, S. P., Goodall, E., & Silverstone, T. (1996) · International Clinical Psychopharmacology · doi:10.1097/00004850-199606000-00003 · Cited by 32
Coventry, P. A., Lovell, K., Dickens, C. M., Bower, P., Chew-Graham, C. A., Cherrington, A., Garrett, C., Sidey-Gibbons, C. J., Baguley, C., Roughley, K., et al. (2012) · Trials · doi:10.1186/1745-6215-13-139 · Cited by 30
Self-citationBrockmeier, L. L., Kromrey, J. D., & Hogarty, K. Y. (2003) · General Linear Model Journal · Cited by 7
Coventry, P. A., Lovell, K., Dickens, C. M., Bower, P., Chew-Graham, C. A., Cherrington, A., Garrett, C., Sidey-Gibbons, C. J., Baguley, C., Roughley, K., et al. (2013) · Trials · doi:10.1186/1745-6215-14-136 · Cited by 6
Self-citationThe ABC‐E Model of Emotion: a bio‐psychosocial model for primary mental health care
Briddon, J., Baguley, C., & Webber, M. (2008) · The Journal of Mental Health Training Education and Practice · doi:10.1108/17556228200800003 · Cited by 3
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Research works printed but not linked: 2
- [23]NICE. Depression. The treatment and management of depression in adults (updated edition). NICE Clinical Guidelines, No 90. British Psychological Society, 2010. 22132433
- [26]Derogatis LR, Cleary PA. Confirmation of the dimensional structure of the scl-90: a study in construct validation. J Clin Psychol 1977; 33: 981-89.
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Sorted by citations
Firth, J., Siddiqi, N., Koyanagi, A., Siskind, D., Rosenbaum, S., Galletly, C., Allan, S., Caneo, C., Carney, R., Carvalho, A. F., et al. (2019) · The Lancet Psychiatry · doi:10.1016/s2215-0366(19)30132-4 · Cited by 1,531
Self-citationTime for united action on depression: a Lancet–World Psychiatric Association Commission
Herrman, H., Patel, V., Kieling, C., Berk, M., Buchweitz, C., Cuijpers, P., Furukawa, T. A., Kessler, R. C., Kohrt, B. A., Maj, M., et al. (2022) · The Lancet · doi:10.1016/s0140-6736(21)02141-3 · Cited by 1,104
Smith, S. M., Wallace, E., O’Dowd, T., & Fortin, M. (2016) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006560.pub3 · Cited by 921
Multimorbidity and depression: A systematic review and meta-analysis
Read, J. R., Sharpe, L., Modini, M., & Dear, B. F. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.06.009 · Cited by 869
Psychological interventions for coronary heart disease.
Richards, S. H., Anderson, L., Jenkinson, C. E., Whalley, B., Rees, K., Davies, P., Bennett, P., Liu, Z., West, R., Thompson, D. R., et al. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002902.pub4 · Cited by 571
Metadata
- Authors
- Coventry, P., Lovell, K., Dickens, C., Bower, P., Chew-Graham, C., McElvenny, D., Hann, M., Cherrington, A., Garrett, C., Gibbons, C. J., Baguley, C., Roughley, K., Adeyemi, I., Reeves, D., Waheed, W., & Gask, L.
- Affiliations
- Manchester Academic Health Science Centre (GB)
- University of Exeter (GB)
- National Institute for Health and Care Research (GB)
- Keele University (GB)
- Health Education North West (GB)
- University of Liverpool (GB)
- Lancashire Care NHS Foundation Trust (GB)
- Corresponding author
- Coventry, P.
- ORCID
- Venue
- BMJ
- Publisher
- BMJ
- Published
- 2015-02-16
- Volume
- 350
- Issue
- feb16 3
- Pages
- h638-h638
- ISSN
- 1756-1833 (ISSN-L)
- PMC
- PMC4353275
- OpenAlex
- W2112219174
- Cited by
- 325
- References
- 69
- Citations by year
- 2026: 19 · 2025: 22 · 2024: 30 · 2023: 13 · 2022: 27 · 2021: 28 · 2020: 39 · 2019: 31 · 2018: 35 · 2017: 25 · 2016: 37 · 2015: 19
- FWCI
- 63.27
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc
- Locations
- BMJ (publishedVersion, cc-by-nc)
- Europe PMC (PubMed Central) (publishedVersion, cc-by-nc)
- PubMed Central (publishedVersion, cc-by-nc)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion, cc-by-nc)
- Figshare (submittedVersion)
- Open Research Exeter (University of Exeter) (submittedVersion, cc-by-nc)
- Funders
- National Institute for Health and Care Research
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Epidemiology › Chronic Disease Management Strategies
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- collaborative care, depression, multimorbidity, diabetes mellitus, cardiovascular disease, integrated primary care, behavioral activation, cognitive restructuring, graded exposure, practice nurses, self-management, quality of life, disability, relapse prevention, patient satisfaction, patient-centered care, general practice, anxiety symptoms, self-efficacy, social support
- MeSH terms
- Cardiovascular Diseases, Depression, Female, Humans, Male, Middle Aged, Patient Care Team, Primary Health Care, Cluster Analysis, Delivery of Health Care, Integrated, Diabetes Complications
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