Cited by 116Long-Term Effects of COVID-19Medical Practices and RehabilitationTraumatic Brain Injury Research

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Conceptualising Long COVID as an episodic health condition

Open access
Brown, Darren A, O’Brien, Kelly K·2021·BMJ Global Health

Abstract

### Summary box Globally growing numbers of individuals are living with persistent signs and symptoms following infection consistent with COVID-19, referred to as Long COVID or Post-COVID Conditions. An estimated 6.2% of the U K population self-identified experiencing Long COVID, which negatively affected their general well-being and ability to exercise and work.1 Long COVID symptoms also adversely affected day-to-day activities among 64.7% of those self-reporting Long COVID, with 19.3% reporting significant limitations to daily activities.2 The long-term trajectory of Long COVID remains unknown. Therefore, conceptualising disability in Long COVID is essential for better understanding the lived experiences and health-related challenges of people living with and affected by Long COVID, to inform effective rehabilitation approaches and interventions to enhance clinical practice, policy and research. Our aim is to conceptualise Long COVID as an episodic health condition resulting in disability that may be characterised as multidimensional, episodic and unpredictable in nature and to highlight future …

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Crossref · 10.1136/bmjgh-2021-007004

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Figure 1 Examples of potential trajectories of episodic disability in people living with Long COVID. (A) Person with pre-existing disability whose disability is exacerbated by acute COVID-19, with disability remaining high during Long COVID with fluctuations over time. Presents with no trajectory of improvement over time. (B) Person experiencing new high level of disability during acute COVID-19, with continued episodic disability during Long COVID. Presents with a trajectory of episodes of limited improvement over time. (C) Person experiencing new moderate level of disability during acute COVID-19, who recovers after acute illness but during Long COVID experiences triggers that result in development of returning episodic disability. Presents with a slow trajectory of improvement over time.
Figure 1 Examples of potential trajectories of episodic disability in people living with Long COVID. (A) Person with pre-existing disability whose disability is exacerbated by acute COVID-19, with disability remaining high during Long COVID with fluctuations over time. Presents with no trajectory of improvement over time. (B) Person experiencing new high level of disability during acute COVID-19, with continued episodic disability during Long COVID. Presents with a trajectory of episodes of limited improvement over time. (C) Person experiencing new moderate level of disability during acute COVID-19, who recovers after acute illness but during Long COVID experiences triggers that result in development of returning episodic disability. Presents with a slow trajectory of improvement over time.CC BY-NC · PubMed Central

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Citations

Cites

Research works printed but not linked: 11

  1. Ziauddeen N , Gurdasani D , O'Hara ME . Characteristics of Long COVID: findings from a social media survey. medRxiv 2021. · DOI
  2. 10.1186/1477-7525-6-76 · DOI
  3. Solomon, 2018, Trajectories of episodic disability in people aging with HIV: a longitudinal qualitative study, J Int Assoc Provid AIDS Care, 17, 232595821875921, 10.1177/2325958218759210 · DOI
  4. O'Brien, 2019, Characterizing the disability experience among adults living with HIV: a structural equation model using the HIV disability questionnaire (HDQ) within the HIV, health and rehabilitation survey, BMC Infect Dis, 19, 10.1186/s12879-019-4203-0 · DOI
  5. 10.1080/09540121.2013.811209 · DOI
  6. 10.3109/09638288.2013.793408 · DOI
  7. Preston NJ , Parkin A , Makower S . The COVID-19 Yorkshire rehabilitation scale (C19-YRS): application and psychometric analysis in a post-COVID-19 syndrome cohort. medRxiv 2021. · DOI
  8. Tran, 2021, Development and validation of the Long COVID symptom and impact tools, a set of patient-reported instruments constructed from patients' lived experience, Clin Infect Dis
  9. O'Brien, 2015, Reliability and validity of a new HIV-specific questionnaire with adults living with HIV in Canada and ireland: the HIV disability questionnaire (HDQ), Health Qual Life Outcomes, 13, 10.1186/s12955-015-0310-9 · DOI
  10. National Institute for Health Research . Living with COVID19 - Second Review 2021.
  11. 10.1093/ptj/pzaa142 · DOI

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Metadata

Authors
Brown, D. A., & O’Brien, K. K.
Affiliations
  • Chelsea and Westminster Hospital NHS Foundation Trust (GB)
  • University of Toronto (CA)
Corresponding author
O’Brien, Kelly K
Venue
BMJ Global Health
Publisher
BMJ
Published
2021-09
Volume
6
Issue
9
Pages
e007004
ISSN
2059-7908 (ISSN-L)
OpenAlex
W3201236807
Cited by
116
References
1
Citations by year
2026: 5 · 2025: 21 · 2024: 31 · 2023: 30 · 2022: 28 · 2021: 1
FWCI
10.77
Type
journal article
Language
en
Open access
Locations
  • BMJ Global Health (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion, other-oa)
  • PubMed Central (publishedVersion, cc-by-nc)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Canada Research Chairs Program (Not Applicable)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Medical Practices and Rehabilitation
  • Health Sciences › Medicine › Clinical Neurology › Traumatic Brain Injury Research
Keywords
long COVID, disability, conceptualization, rehabilitation, lived experience, activity limitation
MeSH terms
COVID-19, SARS-CoV-2, Post-Acute COVID-19 Syndrome, Humans

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