Cited by 46Physical Activity and HealthObesity, Physical Activity, DietSports and Physical Education Studies

Objectively measured physical activity and sedentary time: cross-sectional and prospective associations with adiposity in the Millennium Cohort Study

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Griffiths, Lucy J, Sera, Francesco, Cortina-Borja, Mario, Law, Catherine, Ness, Andrew, Dezateux, Carol·2016·BMJ Open

Abstract

Objective: To examine whether physical activity (PA) and sedentary time (ST) in primary school-aged children are associated with adiposity at the start of secondary school, and whether these associations differ by sex or ethnic group. Design: Nationally representative prospective cohort study. Setting: Children born across the UK, between 2000 and 2002. Participants: 6497 singleton children. Outcome measures: Measures of adiposity (body mass index (BMI), fat mass index (FMI) and fat free mass index (FFMI))—obtained at 7 and 11 years. Explanatory measures: Total daily PA (mean counts per minute (cpm)); minutes of moderate-to-vigorous PA (MVPA); and ST. All assessed at 7 years using accelerometers. Results: In cross-sectional analyses, total PA was inversely associated with FMI (3.7% (95% CI 2.7% to 4.7%) reduction per 150 cpm increase), as was MVPA (4.2% (CI 3.2% to 5.2%) reduction per 20 min/day increase). Associations were stronger in black and South Asian ethnic groups. Total PA and MVPA were not associated with FFMI. ST was positively associated with FMI (1.3% (CI 0.2% to 2.3%) increase per 50 min/day increase) and inversely associated with FFMI (0.5% (CI 0.2% to 0.7%) reduction per 50 min/day increase). Longitudinally, MVPA at age 7 years remained inversely associated with FMI at age 11 years (1.5% (CI 0.4% to 2.6%) reduction per 20 min/day increase). No association was found between total PA and ST and any of the later adiposity measures. Conclusions: 7-year-old children who are more physically active are less likely to be obese at that age and at age 11 years. These associations were particularly evident in children from black or South Asian ethnicity at age 7 years and in boys at age 11 years. Measurements of fat mass provide valuable insights into ethnic differences in associations between adiposity and activity.

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Authors
Griffiths, L. J., Sera, F., Cortina-Borja, M., Law, C., Ness, A., & Dezateux, C.
Affiliations
  • University College London (GB)
  • Clinical Epidemiology, Nutrition and Biostatistics, UCL Institute of Child Health, London, UK
  • Department of Oral and Dental Science, University of Bristol, Bristol, UK
Corresponding author
Griffiths, Lucy J
Venue
BMJ Open
Publisher
BMJ
Published
2016-04
Volume
6
Issue
4
Pages
e010366
ISSN
2044-6055 (ISSN-L)
OpenAlex
W2337180448
Cited by
46
References
64
Citations by year
2026: 2 · 2025: 2 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 4 · 2020: 9 · 2019: 6 · 2018: 5 · 2017: 5 · 2016: 5 · 2015: 1
FWCI
5.63
Type
journal article
Language
en
Open access
Licence
cc-by
Locations
  • BMJ Open (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • Florence Research (University of Florence) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
  • Bristol Research (University of Bristol) (submittedVersion, cc-by-nc)
  • Explore Bristol Research (submittedVersion, cc-by-nc)
Funders
Wellcome Trust (084686/Z/08/A)
Topics
  • Health Sciences › Medicine › Physiology › Physical Activity and Health
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
  • Social Sciences › Life-span and Life-course Studies › Sports and Physical Education Studies
Keywords
physical activity, sedentary time, childhood adiposity, body mass index, fat mass index, fat-free mass index, moderate-to-vigorous physical activity, accelerometer-measured activity, ethnic differences, sex differences, Millennium Cohort Study, obesity prevention
MeSH terms
Child, Cross-Sectional Studies, Female, United Kingdom, Humans, Longitudinal Studies, Male, Obesity, Prospective Studies, Exercise, Body Mass Index, Linear Models, Adiposity, Sedentary Behavior

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