Oncology to specialised palliative home care systematic transition: the Domus randomised trial
Abstract
Objectives To assess the effect of a systematic, fast-track transition from oncological treatment to specialised palliative care at home on symptom burden, to explore intervention mechanisms through patient and intervention provider characteristics and to assess long-term survival and place of death. Measures The effect of a systematic, fast-track transition from oncological treatment to specialised palliative care at home on patient symptom burden was studied in the Domus randomised clinical trial. Participants had incurable cancer and limited treatment options. The intervention was provided by specialised palliative home teams (SPT) based in hospice or hospital and was enriched with a psychological intervention for patient and caregiver dyad. Symptom burden was measured with Edmonton Symptom Assessment System (ESAS-r) at baseline, 8 weeks and 6 months follow-up and analysed with mixed models. Survival and place of death was analysed with Kaplan-Meier and Fisher's exact tests. Results The study included 322 patients. Tiredness was significantly improved for the Domus intervention group at 6 months while the other nine symptom outcomes were not significantly different from the control group. Exploring the efficacy of intervention provider demonstrated significant differences in favour of the hospice SPT on four symptoms and total symptom score. Patients with children responded more favourably to the intervention. The long-term follow-up demonstrated no differences between the…
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Los equipos especializados de cuidados paliativos domiciliarios tienen un efecto favorecedor en la mejora total de los síntomas, aunque el grupo a largo plazo no muestra diferencias con el grupo de control.
“los equipos especializados de cuidados paliativos domiciliarios tuvieron un efecto favorecedor en la mejora total de los síntomas, aunque el grupo a largo plazo no mostró diferencias con el grupo de control.”
From Sobrecarga de trabajo en cuidadores de pacientes en cuidados paliativos oncológicos: Una revisión bibliográfica (2023) · cites this paper as Benthien et al., 2020
Una transición sistemática y rápida de la terapia oncológica a los cuidados paliativos domiciliarios mejora significativamente el cansancio a los 6 meses.
“En este artículo una transición sistemática de y rápida de la terapia oncológica a los cuidadores paliativos mejoró el cansancio significativamente a los 6 meses”
From Sobrecarga de trabajo en cuidadores de pacientes en cuidados paliativos oncológicos: Una revisión bibliográfica (2023) · cites this paper as Benthien et al., 2020
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Villa Clavijo, C. G., Feijoo Espinosa, M. A., Huayllasaca Sarmiento, W. C., Chávez Prieto, H. S., & Cualchi Alvarracin, G. P. (2023) · Ciencia Latina Revista Científica Multidisciplinar · doi:10.37811/cl_rcm.v7i2.6094
- Authors
- Benthien, K., Diasso, P., von Heymann, A., Nordly, M., Kurita, G., Timm, H., Johansen, C., Kjellberg, J., von der Maase, H., & Sjøgren, P.
- Affiliations
- Frederiksberg Hospital (DK)
- Copenhagen University Hospital (DK)
- University of Southern Denmark (DK)
- VIVE - The Danish Center for Social Science Research (DK)
- Corresponding author
- Benthien, Kirstine
- ORCID
- Venue
- BMJ Supportive & Palliative Care
- Publisher
- BMJ
- Published
- 2020-07-17
- Volume
- 10
- Issue
- 3
- Pages
- 350-357
- ISSN
- 2045-435X (ISSN-L)
- 2045-4368
- OpenAlex
- W3043475256
- Cited by
- 18
- References
- 0
- Citations by year
- 2025: 1 · 2024: 7 · 2023: 2 · 2022: 3 · 2021: 5
- FWCI
- 1.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- BMJ Supportive & Palliative Care (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- The Tryg Foundation
- The Danish Cancer Society
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Keywords
- symptom burden, fatigue, hospice care, place of death, long-term survival, incurable cancer, children of cancer patients
- MeSH terms
- Adult, Child, Fatigue, Female, Home Care Services, Humans, Male, Medical Oncology, Middle Aged, Neoplasms, Palliative Care, Patient Transfer, Caregivers, Outcome Assessment, Health Care
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