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The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.

UK guidelines for the management of acute pancreatitis

Open access
·2005·Gut

Abstract

DiagnosisN *The correct diagnosis of acute pancreatitis should be made in all patients within 48 hours of admission (recommendation grade C).N The aetiology of acute pancreatitis should be determined in at least 80% of cases and no more than 20% should be classified as idiopathic (recommendation grade B).N Although amylase is widely available and provides acceptable accuracy of diagnosis, where lipase estimation is available it is preferred for the diagnosis of acute pancreatitis (recommendation grade A).N Where doubt exists, imaging may be used: ultrasonography is often unhelpful and pancreatic imaging by contrast enhanced computed tomography provides good evidence for the presence or absence of pancreatitis (recommendation grade C). AssessmentN The definitions of severity, as proposed in the Atlanta criteria, should be used.However, organ failure present within the first week, which resolves within 48 hours, should not be considered an indicator of a severe attack of acute pancreatitis (recommendation grade B).N Available prognostic features which predict complications in acute pancreatitis are clinical impression of severity, obesity, or APACHE II.8 in the first 24 hours of admission, and C reactive protein .150mg/l, Glasgow score 3 or more, or persisting organ failure after 48 hours in hospital (recommendation grade B).N Patients with persisting organ failure, signs of sepsis, or deterioration in clinical status 6-10 days after admission will require computed tomography (recommendation grade B). Prevention of complicationsN The evidence to enable a recommendation about antibiotic prophylaxis against infection of pancreatic necrosis is conflicting and difficult to interpret.Some trials show benefit, others do not.At present there is no consensus on this issue.N If antibiotic prophylaxis is used, it should be given for a maximum of 14 days (recommen-dation grade B).Further studies are needed (recommendation grade C).

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Metadata

Venue
Gut
Publisher
BMJ
Published
2005-04-14
Volume
54
Issue
suppl 3
Pages
iii1-iii9
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2295572968
Cited by
940
References
46
FWCI
50.30
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: UK guidelines for the management of acute pancreatitis. https://app.cochat.ai/papers/10.1136/gut.2004.057026
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UK guidelines for the management of acute pancreatitis. (2005). Gut. https://doi.org/10.1136/gut.2004.057026

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