The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
BACTERIAL INTERACTIONS WITH CELLS OF THE INTESTINAL MUCOSA: TOLL-LIKE RECEPTORS AND NOD2
Open accessAbstract
Toll-like receptors (TLR) and NOD2 are emerging as key mediators of innate host defence in the intestinal mucosa, crucially involved in maintaining mucosal as well as commensal homeostasis. Recent observations suggest new (patho-) physiological mechanisms of how functional versus dysfunctional TLRx/NOD2 pathways may oppose or favour inflammatory bowel disease (IBD). In health, TLRx signalling protects the intestinal epithelial barrier and confers commensal tolerance whereas NOD2 signalling exerts antimicrobial activity and prevents pathogenic invasion. In disease, aberrant TLRx and/or NOD2 signalling may stimulate diverse inflammatory responses leading to acute and chronic intestinal inflammation with many different clinical phenotypes.
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Cites
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Cited by
The gut flora as a forgotten organ
O'Hara, A. M., & Shanahan, F. (2006) · The EMBO Reports · doi:10.1038/sj.embor.7400731 · Cited by 2,791
Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis
Sartor, R. B. (2006) · Nature Clinical Practice Gastroenterology & Hepatology · doi:10.1038/ncpgasthep0528 · Cited by 1,757
Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens
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Genes and Molecules of Lactobacilli Supporting Probiotic Action
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Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function
Cario, E., Gerken, G., & Podolsky, D. K. (2007) · Gastroenterology · doi:10.1053/j.gastro.2007.02.056 · Cited by 697
Self-citation
Metadata
- Authors
- Cario, E.
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2005-08-01
- Volume
- 54
- Issue
- 8
- Pages
- 1182-1193
- ISSN
- 0017-5749 (ISSN-L)
- OpenAlex
- W2012466772
- Cited by
- 351
- References
- 156
- FWCI
- 11.91
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Cario, E. (2005). BACTERIAL INTERACTIONS WITH CELLS OF THE INTESTINAL MUCOSA: TOLL-LIKE RECEPTORS AND NOD2. Gut. https://doi.org/10.1136/gut.2004.062794
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