Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function

Innate immune recognition

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Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

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Inflammatory Bowel Disease

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Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between Toll-like receptors

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PI3K: Downstream AKTion Blocks Apoptosis

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Differential Alteration in Intestinal Epithelial Cell Expression of Toll-Like Receptor 3 (TLR3) and TLR4 in Inflammatory Bowel Disease

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Cutting Edge: TLR2-Deficient and MyD88-Deficient Mice Are Highly Susceptible to Staphylococcus aureus Infection1

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The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

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Essential role for TIRAP in activation of the signalling cascade shared by TLR2 and TLR4

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NOD2 is a negative regulator of Toll-like receptor 2–mediated T helper type 1 responses

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Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors

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Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin Filaments

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Toll-like receptor 2–mediated NF-κB activation requires a Rac1-dependent pathway

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Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis

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Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

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A Novel Polymorphism in the Toll-Like Receptor 2 Gene and Its Potential Association with Staphylococcal Infection

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Characteristics of Intestinal Dendritic Cells in Inflammatory Bowel Diseases

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Apoptosis: Activate NF-κB or die?

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A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide.

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Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis

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Mechanisms of cross hyporesponsiveness to toll-like receptor bacterial ligands in intestinal epithelial cells☆

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Toll-like receptor 2 enhances ZO-1-associated intestinal epithelial barrier integrity via protein kinase C

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A Toll-Like Receptor 2 Ligand Stimulates Th2 Responses In Vivo, via Induction of Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and c-Fos in Dendritic Cells

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Cox-2 Is Regulated by Toll-Like Receptor-4 (TLR4) Signaling: Role in Proliferation and Apoptosis in the Intestine

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Toll-like receptor 9–induced type I IFN protects mice from experimental colitis

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Hypoxia-Inducible Factor 1–Dependent Induction of Intestinal Trefoil Factor Protects Barrier Function during Hypoxia

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Cutting Edge: Activation of Toll-Like Receptor 2 Induces a Th2 Immune Response and Promotes Experimental Asthma

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Toll-like receptor 2 signaling modulates the functions of CD4 + CD25 + regulatory T cells

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Human Intestinal Epithelial Cells Are Broadly Unresponsive to Toll-Like Receptor 2-Dependent Bacterial Ligands: Implications for Host-Microbial Interactions in the Gut

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Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation.

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BACTERIAL INTERACTIONS WITH CELLS OF THE INTESTINAL MUCOSA: TOLL-LIKE RECEPTORS AND NOD2

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Strategic Compartmentalization of Toll-Like Receptor 4 in the Mouse Gut

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Role of Toll-like Receptors in Spontaneous Commensal-Dependent Colitis

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Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases

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CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: A possible role in ulcerative colitis

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Gliadin Stimulation of Murine Macrophage Inflammatory Gene Expression and Intestinal Permeability Are MyD88-Dependent: Role of the Innate Immune Response in Celiac Disease

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Chitinase 3–Like-1 Exacerbates Intestinal Inflammation by Enhancing Bacterial Adhesion and Invasion in Colonic Epithelial Cells

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Role of tumor necrosis factor receptor 2 (TNFR2) in colonic epithelial hyperplasia and chronic intestinal inflammation in mice

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Synthetic lipopeptide analogs of bacterial lipoprotein are potent polyclonal activators for murine B lymphocytes.

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TLR2 Agonist Ameliorates Established Allergic Airway Inflammation by Promoting Th1 Response and Not via Regulatory T Cells

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TLRs Regulate the Gatekeeping Functions of the Intestinal Follicle-Associated Epithelium

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Phosphoinositide 3-Kinase and Akt Occupy Central Roles in Inflammatory Responses of Toll-Like Receptor 2-Stimulated Neutrophils

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Intestinal epithelial Tollerance versus inTollerance of commensals

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IL-10 Gene-Deficient Mice Lack TGF-β/Smad Signaling and Fail to Inhibit Proinflammatory Gene Expression in Intestinal Epithelial Cells after the Colonization with Colitogenic Enterococcus faecalis

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INVOLVEMENT OF INTERLEUKIN-1 IN THE DEVELOPMENT OF ULCERATIVE COLITIS INDUCED BY DEXTRAN SULFATE SODIUM IN MICE

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CpG Motifs of Bacterial DNA Essentially Contribute to the Perpetuation of Chronic Intestinal Inflammation

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Protein kinase C-α overexpression stimulates Akt activity and suppresses apoptosis induced by interleukin 3 withdrawal

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New Players in TLR-Mediated Innate Immunity: PI3K and Small Rho GTPases

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Th2 Cytokines Down-Regulate TLR Expression and Function in Human Intestinal Epithelial Cells

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TLR5-Mediated Phosphoinositide 3-Kinase Activation Negatively Regulates Flagellin-Induced Proinflammatory Gene Expression

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Epithelial cells pay a Toll for protection

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Trypsin-Sensitive Modulation of Intestinal Epithelial MD-2 as Mechanism of Lipopolysaccharide Tolerance

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IL-6 protects enterocytes from hypoxia-induced apoptosis by induction of bcl-2 mRNA and reduction of fas mRNA.

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Gut microbiota in health and disease

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The gut microbiota--masters of host development and physiology

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Role of the normal gut microbiota

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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

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Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function

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Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components1,2

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Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

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The intestinal epithelium: central coordinator of mucosal immunity

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Intestinal barrier function in health and gastrointestinal disease

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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

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Regulation of Intestinal Barrier Function by Microbial Metabolites

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The microbiome in infectious disease and inflammation

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Regulation of human epithelial tight junction proteins by Lactobacillus plantarum in vivo and protective effects on the epithelial barrier

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Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview

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Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases

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Reshaping faecal gut microbiota composition by the intake of trans-resveratrol and quercetin in high-fat sucrose diet-fed rats

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Commensal bacteria-dependent indole production enhances epithelial barrier function in the colon

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Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function

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Role of the microbiota in inflammatory bowel diseases

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International Society of Sports Nutrition Position Stand: Probiotics

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An exposome perspective: Early-life events and immune development in a changing world

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The role of Akkermansia muciniphila in obesity, diabetes and atherosclerosis

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Duodenal microbiota composition and mucosal homeostasis in pediatric celiac disease

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TLR2 and TLR4 in Parkinson’s disease pathogenesis: The environment takes a toll on the gut

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Microbiota and Probiotics in Health and HIV Infection

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