Cited by 72Gastrointestinal motility and disordersFood composition and propertiesEnhanced Recovery After Surgery

Effect of bran particle size on gastric emptying and small bowel transit in humans: a scintigraphic study.

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Vincent, R, Roberts, A, Frier, M, Perkins, A C, MacDonald, I A, Spiller, R C·1995·Gut

Abstract

Bran is an effective treatment for constipation but its use is often limited by heartburn and bloating. This study examined the effect of fine and coarse bran (15 g) on the gastric emptying and small bowel transit of a 325 kcal rice test meal. Twelve healthy volunteers underwent a three way cross over study, ingesting the technetium-99m labelled rice meal with or without 15 g of indium-111m labelled fine or coarse bran, in random order. Serial scintigraphic images were obtained to define gastric emptying and colonic arrival of label. Compared with control values (99 (9) minutes) (mean (SEM)), the time to 50% gastric emptying was significantly delayed by coarse but not fine bran, being 121 (6) and 104 (9) minutes respectively, p < 0.05, n = 12. Fundal emptying was unchanged but both brans seemed to increase the proportion of isotope in the antrum at 90 minutes. Small bowel transit was slightly faster with both bran types but in this study the difference was not significant. Both the bran and rice labels moved down the gut without significant separation. Fine bran causes less disturbance of gastric physiology than coarse bran.

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  1. 50t on August 20, 2023 by guest. Protected by copyright. http://gut.bmj.com/ Gut: first published as 10.1136/gut.37.2.216 on 1 August 1995. Downloaded from
  2. Hausken T, Berstdt A. Wide gastric antrum in patients with non-ulcer dyspepsia. Scand J Gastroenterol 1992; 27: 427-32.
  3. Meyer JH, Elashoff GJ, Reedy T, Dressman J, Amidon G. Effects of viscosity and fluid outflow on postcibal gastric emptying of solids. Am JPhysiol 19086; 250: G161-4.
  4. Meyer S, Calloway DH. Gastrointestinal response to oat and wheat milling fractions in older women. Cereal Chem 1977; 54: 110-9.

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Authors
Vincent, R., Roberts, A., Frier, M., Perkins, A. C., MacDonald, I. A., & Spiller, R. C.
Affiliations
Queen's Medical Centre (GB)
Venue
Gut
Publisher
BMJ
Published
1995-08
Volume
37
Issue
2
Pages
216-219
ISSN
  • 0017-5749 (ISSN-L)
  • 1468-3288
OpenAlex
W2004699839
Cited by
72
References
21
Citations by year
2025: 1 · 2024: 2 · 2023: 3 · 2021: 2 · 2020: 4 · 2019: 4 · 2018: 3 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 1 · 2013: 5 · 2012: 3
FWCI
3.57
Type
journal article
Language
en
Open access
Locations
  • Gut (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
  • Health Sciences › Medicine › Surgery › Enhanced Recovery After Surgery
Keywords
bran particle size, gastric emptying, small intestinal transit, constipation treatment, technetium-99m scintigraphy, colonic transit
MeSH terms
Adult, Colon, Dietary Fiber, Female, Gastric Emptying, Gastrointestinal Transit, Humans, Indium Radioisotopes, Intestine, Small, Male, Particle Size, Radionuclide Imaging, Oryza, Stomach, Technetium, Triticum

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