From comic relief to real understanding; how intestinal gas causes symptoms
Open accessAbstract
Gas content and transit appear to conspire with the motor and sensory responses of the gut to produce gas related symptoms, both in normal individuals and especially in patients with irritable bowel syndrome (IBS). In relation to gas in IBS, two questions need to be addressed: do IBS patients produce more gas and what are the relationships between intestinal gas and symptoms? The balance of evidence seems to indicate that distension is a real phenomenon in IBS and that such distension accurately reflects gas content. More problematic is extrapolation of the observations relating symptoms to gas transit and retention.
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- Authors
- Quigley, E. M. M.
- Affiliations
- Cork University Hospital (IE)
- Corresponding author
- Quigley, E M M
- ORCID
- Quigley, E M M
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2003-11-21
- Volume
- 52
- Issue
- 12
- Pages
- 1659.1-1661
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- PMC
- PMC1773900
- OpenAlex
- W2119208124
- Semantic Scholar
- 5043e713289dc25cdbe18c992e3e84c5834c93af
- Cited by
- 31
- References
- 40
- Citations by year
- 2024: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 2 · 2012: 3
- FWCI
- 2.90
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Gut (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Lenus, The Irish Health Repository (Dr Steevens Hospital Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Health Professions › Pharmacy › Infant Health and Development
- Keywords
- intestinal gas, irritable bowel syndrome, distension, gas transit, gas retention, intestinal motility
- MeSH terms
- Eructation, Flatulence, Gases, Gastrointestinal Transit, Humans, Intestines, Sensation, Irritable Bowel Syndrome
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