The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Hospitalisations and surgery in Crohn's disease
Abstract
Hospitalisation and surgery are considered to be markers of more severe disease in Crohn's disease. These are costly events and limiting these costs has emerged as one rationale for the cost of expensive biologic therapies. The authors sought to review the most recent international literature to estimate current hospitalisation and surgery rates for Crohn's disease and place them in the historical context of where they have been, whether they have changed over time, and to compare these rates across different jurisdictions. It is in this context that the authors could set the stage for interpreting some of the early data and studies that will be forthcoming on rates of hospitalisation and surgery in an era of more aggressive biologic therapy. The most recent data from Canada, the United Kingdom and Hungary all suggest that surgical rates were falling prior to the advent of biologic therapy, and continue to fall during this treatment era. The impact of biologic therapy on surgical rates will have to be analysed in the context of evolving reductions in developed regions before biologic therapy was even introduced. Whether more aggressive medical therapy will decrease the requirement for surgery over long periods of time remains to be proven.
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Cites
The Natural History of Adult Crohn's Disease in Population-Based Cohorts
Peyrin-Biroulet, L., Loftus, E. V., Colombel, J.-F., & Sandborn, W. J. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2009.579 · Cited by 1,047
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Clinical Course in Crohn’s Disease: Results of a Norwegian Population-Based Ten-Year Follow-Up Study
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Self-citationCosnes, J., Nion-Larmurier, I., Beaugerie, L., Afchain, P., Tiret, E., & Gendre, J.-P. (2005) · Gut · doi:10.1136/gut.2004.045294 · Cited by 657
Risk Factors for Surgery and Postoperative Recurrence in Crohn’s Disease
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Long-term follow-up of patients with Crohn's disease
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Long-term follow-up of patients with Crohn's disease
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Cited by
The burden of inflammatory bowel disease in Europe
Burisch, J., Jess, T., Martinato, M., & Lakatos, P. L. (2013) · Journal of Crohn's and Colitis · doi:10.1016/j.crohns.2013.01.010 · Cited by 961
Self-citationFrolkis, A. D., Dykeman, J., Negrón, M. E., deBruyn, J., Jette, N., Fiest, K. M., Frolkis, T., Barkema, H. W., Rioux, K. P., Panaccione, R., et al. (2013) · Gastroenterology · doi:10.1053/j.gastro.2013.07.041 · Cited by 892
Burisch, J., Pedersen, N., Čuković-Čavka, S., Brinar, M., Kaimakliotis, I., Duricova, D., Shonová, O., Vind, I., Avnstrøm, S., Thorsgaard, N., et al. (2014) · Gut · doi:10.1136/gutjnl-2013-304636 · Cited by 429
Self-citationScharl, M., Huber, N., Lang, S., Fürst, A., Jehle, E., & Rogler, G. (2015) · Clinical and Translational Medicine · doi:10.1186/s40169-015-0046-5 · Cited by 118
Predictors and risks for death in a population-based study of persons with IBD in Manitoba
Bernstein, C. N., Nugent, Z., Targownik, L. E., Singh, H., & Lix, L. M. (2015) · Gut · doi:10.1136/gutjnl-2014-307983 · Cited by 72
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Metadata
- Authors
- Bernstein, C. N., Loftus, E. V., Ng, S. C., Lakatos, P. L., & Moum, B.
- Venue
- Gut
- Publisher
- BMJ
- Published
- 2012-01-20
- Volume
- 61
- Issue
- 4
- Pages
- 622-629
- ISSN
- 0017-5749 (ISSN-L)
- 1468-3288
- OpenAlex
- W2113143571
- Cited by
- 294
- References
- 41
- FWCI
- 16.83
- Type
- journal article
- Language
- en
- Open access
- closed
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