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Cited by 51Health disparities and outcomesCardiovascular Health and Risk FactorsCardiac Health and Mental Health

Neighbourhood socioeconomic status and coronary heart disease in individuals between 40 and 50 years

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Carlsson, Axel C, Li, Xinjun, Holzmann, Martin J, Wändell, Per, Gasevic, Danijela, Sundquist, Jan, Sundquist, Kristina·2016·Heart
DOI 10.1136/heartjnl-2015-308784PMC PMC4846504
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Abstract

Objective: The incidence of myocardial infarction (MI) has decreased in general but not among younger middle-aged adults. We performed a cohort study of the association between neighbourhood socioeconomic status (SES) at the age of 40 and risk of MI before the age of 50 years. Methods: All individuals in Sweden were included in the year of their 40th birthday, if it occurred between 1998 and 2010. National registers were used to categorise neighbourhood SES into high, middle and low, and to retrieve information on incident MI and coronary heart disease (CHD). Cox regression models, adjusted for marital status, education level, immigrant status and region of residence, provided an estimate of the HRs and 95% CIs for MI or CHD. Results: Out of 587 933 men and 563 719 women, incident MI occurred in 2877 (0.48%) men and 932 (0.17%) women; and CHD occurred in 4400 (0.74%) men and 1756 (0.31%) women during a mean follow-up of 5.5 years. Using individuals living in middle-SES neighbourhoods as referents, living in high-SES neighbourhoods was associated with lower risk of MI in both sexes (HR (95% CI): men: 0.72 (0.64 to 0.82), women: 0.66 (0.53 to 0.81)); living in low-SES neighbourhoods was associated with a higher risk of MI (HR (95% CI): men: 1.31 (1.20 to 1.44), women: 1.28 (1.08 to 1.50)). Similar risk estimates for CHD were found. Conclusions: The results of our study suggest an increased risk of MI and CHD among residents from low-SES neighbourhoods and a lower risk in those from high-SES neighbourhoods compared with residents in middle-SES neighbourhoods.

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  • Lower individual and neighborhood-level SES are associated with increased incidence and prevalence of CVD, including coronary heart disease, heart failure and stroke.

    “Lower individual and neighborhood-level SES are associated with an increased incidence and prevalence of CVD, including coronary heart disease, heart failure and stroke [1,[3], [4], [5], [6]].”

    From Income disparity and utilization of cardiovascular preventive care services among U.S. adults (2021) · cites this paper as [3]

    The Conclusions (page not available in our copy) report increased risk of premature myocardial infarction and coronary heart disease among younger middle-aged Swedes in lower-SES neighbourhoods, independent of measured individual socioeconomic factors. The Introduction says individual and neighbourhood SES shape cardiovascular risk factors, but the paper does not establish the claimed associations with CVD prevalence, heart failure or stroke, or a separate increase in CVD incidence associated with lower individual SES. (LLM, conf=0.88)

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Research works printed but not linked: 24

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Authors
Carlsson, A. C., Li, X., Holzmann, M. J., Wändell, P., Gasevic, D., Sundquist, J., & Sundquist, K.
Affiliations
  • Uppsala University (SE)
  • Lund University (SE)
  • Karolinska University Hospital (SE)
  • Karolinska Institutet (SE)
  • Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, UK
Corresponding author
Carlsson, Axel C
ORCID
Venue
Heart
Publisher
BMJ
Published
2016-02-10
Volume
102
Issue
10
Pages
775-782
ISSN
  • 1355-6037 (ISSN-L)
  • 1468-201X
DOI
10.1136/heartjnl-2015-308784
PMC
PMC4846504
OpenAlex
W2336262844
Cited by
51
References
5
Citations by year
2026: 2 · 2025: 6 · 2024: 2 · 2023: 5 · 2022: 8 · 2021: 6 · 2020: 2 · 2019: 5 · 2018: 10 · 2017: 5
FWCI
8.81
Type
journal article
Language
en
Open access
Locations
  • Heart (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
  • Lund University Publications (Lund University) (submittedVersion)
  • HighWire Press Open Archive (submittedVersion)
  • Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, other-oa)
Funders
National Heart, Lung, and Blood Institute (R01HL116381)
Topics
  • Social Sciences › Health › Health disparities and outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Health and Mental Health
Keywords
neighborhood socioeconomic status, coronary artery disease, myocardial infarction, middle-aged adults, young adults, cardiovascular risk, sex differences, immigrant status, educational attainment
MeSH terms
Adult, Coronary Disease, Female, Humans, Male, Middle Aged, Myocardial Infarction, Registries, Residence Characteristics, Risk Factors, Socioeconomic Factors, Sweden, Time Factors, Incidence, Proportional Hazards Models, Odds Ratio, Age of Onset, Risk Assessment

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