Epicardial adipose tissue imaged by magnetic resonance imaging: An important risk marker of cardiovascular disease
Open accessAbstract
A 54-year-old woman with diabetes mellitus II and obesity (body mass index (BMI) 40 kg/m2) was referred to the cardiology outpatient clinic because of reduced exercise tolerance. Cardiac magnetic resonance imaging (MRI) (panel) was performed because the echocardiographic examination was insufficient. …
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CMR is considered the gold standard method for EAT quantification, validated even in animal models for research purposes.
“CMR is considered the gold standard method for EAT quantification, validated even in animal models for research purposes [111].”
From Dysregulated epicardial adipose tissue as a risk factor and potential therapeutic target of heart failure with preserved ejection fraction in diabetes (2022) · cites this paper as [111]
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Validation of cardiovascular magnetic resonance assessment of pericardial adipose tissue volume
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Novel imaging biomarkers: epicardial adipose tissue evaluation
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“CMR is considered the gold standard method for EAT quantification, validated even in animal models for research purposes [111].”
MethodZıyrek, M., Kahraman, S., Özdemir, E., & Doğan, A. (2019) · Revista Portuguesa de Cardiologia · doi:10.1016/j.repc.2018.08.010 · Cited by 63 · see citing works
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“EAT area was defined as the fat located between the outer wall of the myocardium and the visceral layer of the pericardium [16].”
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Is epicardial fat tissue a marker of metabolic syndrome in obese children?
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“Finally, imaging of EAT by MRI, rather than the commonly used CT scan, provides a reliable measurement (47,50).”
MethodShamloo, A. S., Schoene, K., Stauber, A., Darma, A., Dagres, N., Dinov, B., Bertagnolli, L., Hilbert, S., Müssigbrodt, A., Husser, D., et al. (2019) · Heart Rhythm · doi:10.1016/j.hrthm.2019.06.009 · Cited by 36 · see citing works
Epicardial Adipose Tissue in Patients with Chronic Obstructive Pulmonary Disease
Zagaceta, J., Zulueta, J. J., Bastarrika, G., Colina, I., Alcaide, A. B., Campo, A., Celli, B. R., & de-Torres, J. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065593 · Cited by 34 · see citing works
“EAT volume can be quantified by different non-invasive radiological techniques, such as echocardiography [13], magnetic resonance imaging (MRI) [14], and computed tomography (CT) [15].”
MethodMetabolic Syndrome and Ectopic Fat Deposition
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“Although magnetic resonance imaging (MRI) and computed tomography (CT) are gold standard methods for quantifying visceral adiposity and EFT, high costs, experience requirement, long acquisition times in MRI, and radiation exposure in CT are other important limitations.(33,34) On the other hand, measurement of EFT by e…”
BackgroundAltın, C., Sade, L. E., Gezmiş, E., Yılmaz, M., Özen, N., & Müderrisoğlu, H. (2016) · Journal of Cardiology · doi:10.1016/j.jjcc.2016.08.006 · Cited by 25 · see citing works
Fast fully automatic heart fat segmentation in computed tomography datasets
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“Further, studies quantifying EAT have utilized various imaging modalities including: echocardiography (16), cardiac magnetic resonance (MR) (17), and multi-detector computed tomography (MDCT) (18).”
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“Although CT and MRI are acknowledged imaging modalities for measuring visceral adiposity, there are some limitations, including professional requirements, costly, radiological hazards in CT, and the time-consuming of MRI [88, 89].”
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“Some observers have shown that volumetric EAT measurement by CT and MRI is more accurate and its reproducibility is superior to linear measurements [47, 48 ] and correlates more accurately with the extension of coronary lesions [49,50].”
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“MRI is considered a gold standard in fat measurement, and CMR can easily distinguish between EAT and pericardial fat [10].”
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- Authors
- Kessels, K., Cramer, M.-J. M., & Velthuis, B.
- Corresponding author
- Kessels, K
- Venue
- Heart
- Publisher
- BMJ
- Published
- 2006-06-14
- Volume
- 92
- Issue
- 7
- Pages
- 962-962
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- PMC
- PMC1860684
- OpenAlex
- W2170026174
- Cited by
- 30
- References
- 0
- Citations by year
- 2025: 2 · 2023: 1 · 2022: 2 · 2019: 6 · 2018: 3 · 2017: 1 · 2016: 2 · 2014: 5 · 2013: 1
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Heart (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Disease and Adiposity
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
- Keywords
- epicardial adipose tissue, cardiac magnetic resonance imaging, cardiovascular risk markers, type 2 diabetes, obesity
- MeSH terms
- Adipose Tissue, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Female, Heart Diseases, Humans, Middle Aged, Pericardium, Risk Factors, Magnetic Resonance Angiography
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