DISEASE OF THE HEART IN THE WORKS OF HIPPOCRATES
Open accessAbstract
He who would make accurate forecasts as to those who will recover, and those who will die, and whether the disease will last a greater or less number of days, must understand all the symptoms thoroughly and be able to appreciate them, estimating their powers when they are compared with one another, as I have set forth. Hippocrates, Prognostic XXV (Jones, 1923-31)
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The concept of the four humours influenced medical paradigms, including those regarding the cardiovascular system, for long centuries to come.
“The concept of the four humours would influence the medical paradigms, including those regarding the cardiovascular system for long centuries to come”
From The discovery of pulmonary circulation: From Imhotep to William Harvey (2014) · cites this paper as [5]
The section labelled Abstract says medicine remained dominated by philosophic doctrines despite anatomical advances. The paper also quotes a speculative explanation linking phlegm to heart palpitation and breathing difficulty. But our copy does not identify the four humours as the influential concept or establish that their influence on cardiovascular medicine lasted for centuries. (LLM, conf=0.76)
Experimental — accuracy not yet measuredThe four humours are blood, black bile, yellow bile, and phlegm.
“These humours are blood, black bile, yellow bile, and phlegm.”
From The discovery of pulmonary circulation: From Imhotep to William Harvey (2014) · cites this paper as [5]
Our copy discusses blood and phlegm in a passage about heart symptoms (section labeled Abstract; page unavailable), but does not identify them as members of a set of four humours. Searches for the four-humour list and for black and yellow bile found no passage establishing the claimed list. (LLM, conf=0.74)
Experimental — accuracy not yet measuredThe four humours correspond to the four elements of nature (earth, wind, fire, and water) that reflect the four primary physical qualities (hot, cold, dry, and wet).
“The four humours correspond to the four elements of nature (earth, wind, fire, and water) that reflect the four primary physical qualities (hot, cold, dry, and wet).”
From The discovery of pulmonary circulation: From Imhotep to William Harvey (2014) · cites this paper as [5]
The paper’s discussion of anatomy and physiology in the Hippocratic collection (indexed under “Abstract”; page unavailable) mentions philosophical doctrines but does not describe a correspondence among four humours, four elements, and four physical qualities. Searches for those terms and for the names of the humours found no passage addressing the claimed correspondence. (LLM, conf=0.77)
Experimental — accuracy not yet measuredHippocrates and his contemporaries theorized that health is a state of balanced humours while disease was a state of imbalanced humours.
“Hippocrates and his contemporaries theorized that health is a state of balanced humours while disease was a state of imbalanced humours.”
From The discovery of pulmonary circulation: From Imhotep to William Harvey (2014) · cites this paper as [5]
The indexed passage labeled Abstract (page unavailable) says that ancient medicine was influenced by philosophical doctrines, but it does not describe health as balanced humours or disease as imbalanced humours. Searches for humours, balance, and the claimed health–disease distinction found no passage in our copy that addresses that theory. (LLM, conf=0.72)
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Bestetti, R. B., Cardinalli-Neto, A., & Couto, L. B. (2020) · International Journal of Cardiology · doi:10.1016/j.ijcard.2019.12.050 · Cited by 7 · see citing works
Figueredo, V. M. (2021) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2021.06.041 · Cited by 7 · see citing works
Pathogenetic aspects of cachexia
Klochkova, I. S., Astafyeva, L. I., Кадашев, Б. А., Sidneva, Y., & Kalinin, P. L. (2020) · Obesity and metabolism · doi:10.14341/omet10173 · Cited by 7 · see citing works
Riva, M. A., Cesana, F., Achilli, F., Scordo, F., & Cesana, G. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.07.104 · Cited by 6 · see citing works
Jiang, X., Chen, Q., Chen, X., Sun, Q., Jing, F., Zhang, H., Xu, J., Li, X., & Guan, Q. (2024) · BMC Cardiovascular Disorders · doi:10.1186/s12872-024-03867-2 · Cited by 5 · see citing works
Alterations in Nutrition and Body Mass in Heart Failure
Doehner, W., von Haehling, S., & Anker, S. D. (2010) · Elsevier eBooks · doi:10.1016/b978-1-4160-5895-3.10021-x · Cited by 5 · see citing works
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Testosterone: The Male Sex Hormone
Obukohwo, O. M., Ben‐Azu, B., Ovuakporaye, S. I., Oghenetega, O. B., Emojevwe, V. O., Faith, F. Y., Okwute, P. G., Rotu, R. A., Godswill, O. O., & Kingsley, N. E. (2023) · IntechOpen eBooks · doi:10.5772/intechopen.110657 · Cited by 4 · see citing works
Adipositas und kardiale Kachexie bei chronischer Herzinsuffizienz
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- Authors
- Katz, A. M., & Katz, P. B.
- Venue
- Heart
- Publisher
- BMJ
- Published
- 1962-05-01
- Volume
- 24
- Issue
- 3
- Pages
- 257-264
- ISSN
- 1355-6037 (ISSN-L)
- PMC
- PMC1017881
- OpenAlex
- W2154397526
- Cited by
- 169
- References
- 7
- Citations by year
- 2026: 21 · 2025: 2 · 2024: 5 · 2023: 4 · 2022: 3 · 2021: 6 · 2020: 12 · 2019: 9 · 2018: 4 · 2017: 6 · 2016: 5 · 2015: 4 · 2014: 4 · 2013: 5 · 2012: 4
- FWCI
- 29.60
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Heart (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Topics
- Social Sciences › Arts and Humanities › History › History of Medicine Studies
- Social Sciences › Arts and Humanities › History and Philosophy of Science › History of Science and Medicine
- Health Sciences › Medicine › Psychiatry and Mental health › Medicine, History, and Philosophy
- Keywords
- Hippocrates, heart disease, ancient Greek medicine, prognosis, cardiac symptoms, history of cardiology
- MeSH terms
- Cardiology, Heart, Humans, Male, Prognosis, Work
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