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Cited by 168

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Natural history of secundum atrial septal defect in adults after medical or surgical treatment: a historical prospective study

Open access
Shah, D, Azhar, M, Oakley, C M, Cleland, J G F, Nihoyannopoulos, P·1994·Heart

Abstract

OBJECTIVE: To compare outcome in patients with medically treated secundum atrial septal defect (ASD) first diagnosed after the age of 25 with the long-term outcome in a similar group of patients after surgical closure. DESIGN: A historical, prospective, unrandomised study. SETTING: A tertiary referral centre. PATIENTS: All patients with ASD followed up since 1955 who fulfilled the entry criteria and had reached a current age of over 45 years--that is, 34 medical and 48 surgical patients with a mean follow up of 25 years. MAIN OUTCOME MEASURES: Survival, symptoms, and complications. RESULTS: There was no difference in survival or symptoms between the two groups and no difference in the incidence of new arrhythmias, stroke or other embolic phenomena, or cardiac failure. No patient in either group developed progressive pulmonary vascular disease. CONCLUSION: Outcome in adults with ASD was not improved by surgical closure. Because progressive pulmonary vascular disease did not develop in any of these patients its prevention is not a reason for advising closure of ASD in adults.

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Crossref · 10.1136/hrt.71.3.224

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Metadata

Authors
Shah, D., Azhar, M., Oakley, C. M., Cleland, J. G. F., & Nihoyannopoulos, P.
Venue
Heart
Publisher
BMJ
Published
1994-03-01
Volume
71
Issue
3
Pages
224-228
ISSN
1355-6037 (ISSN-L)
OpenAlex
W2133906309
Cited by
168
References
1
FWCI
6.07
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Natural history of secundum atrial septal defect in adults after medical or surgical treatment: a historical prospective study. https://app.cochat.ai/papers/10.1136/hrt.71.3.224
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Shah, D., Azhar, M., Oakley, C. M., Cleland, J. G. F., & Nihoyannopoulos, P. (1994). Natural history of secundum atrial septal defect in adults after medical or surgical treatment: a historical prospective study. Heart. https://doi.org/10.1136/hrt.71.3.224

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.