The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
QT dispersion and components of the QT interval in ischaemia and infarction.
Open accessAbstract
OBJECTIVE: To evaluate changes in QT dispersion and components of the QT interval in patients admitted with unstable angina and acute myocardial infarction and to study the dynamics of these changes in patients with infarction. METHODS: Prospective study recording electrocardiograms at 50 mm/s in patients admitted with typical cardiac chest pain. Subsequent confirmation of acute myocardial infarction according to standard criteria. Single blind analysis for QT dispersion and QT components using a digitiser and simple computer program. Results are expressed as native QT dispersion, QTc dispersion, and the QT dispersion ratio defined as QT dispersion divided by cycle length and expressed as a percentage. RESULTS: QT dispersion, QTc dispersion, and QT dispersion ratio were all higher in patients with acute myocardial infarction than in those with unstable angina (mean (SD) 66 (18) ms, 75 (26) ms1/2, and 8.1 (2.4)% compared with 38 (13) ms, 39 (13) ms1/2, and 4.5 (1.7) % respectively). Dynamic changes in QTc dispersion were seen after acute infarction with significant differences in the QT components occurring between the different patient groups. Levels of QT dispersion (87 (15) ms), QTc dispersion (105 (17) ms1/2), and QT dispersion ratio (11.7 (0.8)%) in the four patients with ventricular fibrillation were significantly higher. Use of QT dispersion ratio gave a narrower confidence interval. CONCLUSION: QT dispersion is increased after myocardial infarction and levels are higher in patients with ventricular fibrillation. The changes in QT dispersion are dynamic and may reflect the changing pattern of underlying ventricular recovery of ventricular excitability, which is profoundly disturbed in the earliest phase of acute infarction. Expressing QT dispersion as a percentage of cycle length (QT dispersion ratio) rather than using standard rate correction may be superior in identifying patients who develop ventricular fibrillation.
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Citations
Cites
Janse, M. J., & Wit, A. L. (1989) · Physiological Reviews · doi:10.1152/physrev.1989.69.4.1049 · Cited by 1,018
Importance of lead selection in QT interval measurement
Cowan, J. C., Yusoff, K., Moore, M., Amos, P. A., Gold, A. E., Bourke, J. P., Tansuphaswadikul, S., & Campbell, R. W. F. (1988) · The American Journal of Cardiology · doi:10.1016/0002-9149(88)91309-4 · Cited by 337
Self-citationHypokalaemia and ventricular fibrillation in acute myocardial infarction.
Nordrehaug, J. E., & von der Lippe, G. (1983) · Heart · doi:10.1136/hrt.50.6.525 · Cited by 207
Reduction in QT dispersion by sotalol following myocardial infarction
Day, C. P., McComb, J. M., Matthews, J. N. S., et al. (1991) · European Heart Journal · doi:10.1093/oxfordjournals.eurheartj.a059911 · Cited by 203
El-Sherif, N., Myerburg, R. J., Scherlag, B. J., Befeler, B., Aranda, J. M., Castellanos, A., & Lazzara, R. (1976) · Heart · doi:10.1136/hrt.38.4.415 · Cited by 172
Mechanisms underlying the development of ventricular fibrillation during early myocardial ischemia.
Pogwizd, S. M., & Corr, P. B. (1990) · Circulation Research · doi:10.1161/01.res.66.3.672 · Cited by 140
QT interval variability on the body surface
Sylvén, J. C., Horáček, B. M., Spencer, C., Klassen, G. A., & Montague, T. J. (1984) · Journal of Electrocardiology · doi:10.1016/s0022-0736(84)81093-6 · Cited by 97
Arrhythmias in the first hours of acute myocardial infarction
Pantridge, J. F., Webb, S. W., & Adgey, A. A. J. (1981) · Progress in Cardiovascular Diseases · doi:10.1016/0033-0620(81)90016-5 · Cited by 83
Cited by
Mechanisms of abnormal cardiac repolarization during insulin-induced hypoglycemia
Robinson, R. T. C. E., Harris, N. D., Ireland, R. H., Lee, S., Newman, C., & Heller, S. R. (2003) · Diabetes · doi:10.2337/diabetes.52.6.1469 · Cited by 264
VEGLIO, M., BRUNO, G., BORRA, M., MACCHIA, G., BARGERO, G., D'ERRICO, N., PAGANO, G. F., & CAVALLO‐PERIN, P. (2002) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.2002.00955.x · Cited by 132
Hailer, B., Leeuwen, P. V., Lange, S., & Wehr, M. (1999) · Journal of Electrocardiology · doi:10.1016/s0022-0736(99)90103-6 · Cited by 39
Huang, X., Hua, N., Tang, F., & Zhang, S. (2020) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-20-121 · Cited by 10
Metadata
- Authors
- Higham, P. D., Furniss, S. S., & Campbell, R. W.
- Venue
- Heart
- Publisher
- BMJ
- Published
- 1995-01-01
- Volume
- 73
- Issue
- 1
- Pages
- 32-36
- ISSN
- 1355-6037 (ISSN-L)
- OpenAlex
- W1971790726
- Cited by
- 296
- References
- 8
- FWCI
- 17.13
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
