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Midodrine: a role in the management of neurocardiogenic syncope
Open accessAbstract
Objective: To determine the benefit of midodrine, an α agonist, on symptom frequency and haemodynamic responses during head up tilt in patients with neurocardiogenic syncope. Setting: Cardiovascular investigation unit (a secondary and tertiary referral centre for the investigation and management of syncope). Patients: 16 outpatients (mean (SD) age 56 (18) years; five men) with frequent hypotensive symptoms (more than two syncopal episodes and fewer than 20 symptom free days per month), and reproducible syncope with glyceryl trinitrate (GTN) during head up tilt. Design and intervention: Randomised double blind placebo controlled study. Patients were randomised to receive either placebo or midodrine for one month. Symptom events were recorded during each study month. At the end of each study month patients completed a quality of life scoring scale (Short Form 36) and a global assessment of therapeutic response. They received GTN with head up tilt for measurement of heart rate (electrocardiography), phasic blood pressure (digital photoplethysmography), and thoracic fluid index (transthoracic impedance plethysmography) during symptom provocation. Results: Patients administered midodrine had an average of 7.3 more symptom free days than those who received placebo (95% confidence interval (CI) 4.6 to 9; p < 0.0001). Eleven patients reported a positive therapeutic response with midodrine (p = 0.002). All domains of quality of life showed improvement with midodrine, in particular physical function (8.1; 95% CI 3.7 to 12.2), energy and vitality (14.6; 95% CI 7.3 to 22.1), and change in health status (22.2; 95% CI 11 to 33.4 ). Fourteen patients who were given placebo had tilt induced syncope compared with six given midodrine (p = 0.01). Baseline supine systolic blood pressure was higher and heart rate lower in patients who received midodrine than in those who were given placebo ( p < 0.05). A lower thoracic fluid index in patients administered midodrine indicates increased venous return when supine and during head up tilt. There were no serious adverse effects. Conclusions: Midodrine had a conspicuous beneficial effect on symptom frequency, symptoms during head up tilt, and quality of life. Midodrine is recommended for the treatment of neurocardiogenic syncope in patients with frequent symptoms.
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“None of the studies were conventional, placebo-controlled, randomized clinical trials of moderately to severely symptomatic patients.125–128”
From 2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope (2015) · cites this paper as [127]
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“Four randomized trials on midodrine have shown a consistent risk reduction of approximately 70%.”
From 2015 Heart Rhythm Society Expert Consensus Statement on the Diagnosis and Treatment of Postural Tachycardia Syndrome, Inappropriate Sinus Tachycardia, and Vasovagal Syncope (2015) · cites this paper as [127]
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Cites
MCHORNEY, C. A., JOHNE, W., & ANASTASIAE, R. (1993) · Medical Care · doi:10.1097/00005650-199303000-00006 · Cited by 6,681
Development and evaluation of an impedance cardiac output system.
Kubicek, W. G., Karnegis, J. N., PATTERSON, R. P., Witsoe, D. A., & Mattson, R. H. (1966) · PubMed · Cited by 1,143
HEAD-UP TILT: A USEFUL TEST FOR INVESTIGATING UNEXPLAINED SYNCOPE
Kenny, R. A., Bayliss, J. M., Ingram, A., & Sutton, R. (1986) · The Lancet · doi:10.1016/s0140-6736(86)91665-x · Cited by 777
Self-citationAlmquist, A. K., Goldenberg, I. F., Milstein, S., Chen, M. Y., Chen, X., Hansen, R., Gornick, C. C., & Benditt, D. G. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902093200603 · Cited by 644
Neurogenic orthostatic hypotension: a double-blind, placebo-controlled study with midodrine
Jankovic, J., Gilden, J. L., Hiner, B. C., Kaufmann, H., Brown, D. C., Coghlan, C. H., Rubin, M., & Fouad-Tarazi, F. M. (1993) · The American Journal of Medicine · doi:10.1016/0002-9343(93)90230-m · Cited by 396
Kubicek, W. G., PATTERSON, R. P., & Witsoe, D. A. (1970) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1970.tb17735.x · Cited by 396
Imholz, B. P. M., Settels, J. J., van der Meiracker, A. H., Wesseling, K. H., & Wieling, W. (1990) · Cardiovascular Research · doi:10.1093/cvr/24.3.214 · Cited by 344
van Lieshout, J. J., Wieling, W., Karemaker, J. M., & Eckberg, D. L. (1991) · Clinical Science · doi:10.1042/cs0810575 · Cited by 323
ABI‐SAMRA, F. M., Maloney, J. D., Fouad-Tarazi, F. M., & CASTLE, L. W. (1988) · Pacing and Clinical Electrophysiology · doi:10.1111/j.1540-8159.1988.tb03973.x · Cited by 306
Impairment of physical and psychosocial function in recurrent syncope
Linzer, M., Pontinen, M., Gold, D. T., Divine, G. W., Felder, A., & Blair Brooks, W. (1991) · Journal of Clinical Epidemiology · doi:10.1016/0895-4356(91)90005-t · Cited by 296
Flagged first, then by citations
Research works printed but not linked: 3
- McIntosh, 1996, Use of sublingual glyceryl trinitrate during head-up tilt: a provocative test for reproduction of neurocardiogenic symptoms in unexplained syncope., Cardiology in the Elderly, 4, 33
- Fitzpatrick, 1991, A randomised trial of medical therapy in “malignant vasovagal syndrome” or “neurally-mediated bradycardia/hypotension syndrome”., European Journal of Cardiac Pacing and Electrophysiology, 2, 99
- Erhringer, 1971, Studies on the peripheral haemodynamics in man after intravenous infusion of a small dose of di-1-(2′,5′-dimethoxyphenyl)-2-glycinamido-ethanol-(1)-hydrochloride., Int J Clin Pharmacol Ther Toxicol, 4, 415
Cited by
Sorted by citations
Items 101–200 of 248
Dysautonomia and neurocardiogenic syncope
McLEOD, K. A. (2001) · Current Opinion in Cardiology · doi:10.1097/00001573-200103000-00003 · Cited by 17
Grubb, B. P. (2005) · Wiley eBooks · doi:10.1002/9780470994801.ch2 · Cited by 17
Behnoush, A. H., Yazdani, K., Khalaji, A., Tavolinejad, H., Aminorroaya, A., Jalali, A., & Tajdini, M. (2022) · Heart Rhythm · doi:10.1016/j.hrthm.2022.12.010 · Cited by 16
Neurological Aspects of Syncope and Orthostatic Intolerance
Weimer, L. H., & Zadeh, P. (2009) · Medical Clinics of North America · doi:10.1016/j.mcna.2008.10.002 · Cited by 16
Autonomic dysfunction in older people
Marigold, R., Arias, M., Vassallo, M., Allen, S., & Kwan, J. S. K. (2010) · Reviews in Clinical Gerontology · doi:10.1017/s0959259810000286 · Cited by 14
Midodrine for the treatment of vasovagal syncope (simple FAINT)
Stewart, J. M. (2006) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2006.08.026 · Cited by 14
Does A Therapy for Reflex Vasovagal Syncope Really Exist?
Romano, S. L., Branz, L., Fondrieschi, L., & Minuz, P. (2019) · High Blood Pressure & Cardiovascular Prevention · doi:10.1007/s40292-019-00327-3 · Cited by 13
Midodrine treatment in children with recurrent vasovagal syncope
Bağrul, D., Ece, İ., Yılmaz, A., Atík, F., & Kavurt, A. V. (2021) · Cardiology in the Young · doi:10.1017/s1047951120004746 · Cited by 13
Treatment of Patients With Orthostatic Hypotension and Syncope
Kaufmann, H. (2002) · Clinical Neuropharmacology · doi:10.1097/00002826-200205000-00003 · Cited by 13
How and When to Pace in Vasovagal Syncope
Sutton, R. (2002) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2002.tb01947.x · Cited by 13
PACING TO PREVENT VASOVAGAL SYNCOPE
Sheldon, R. S. (2000) · Cardiology Clinics · doi:10.1016/s0733-8651(05)70129-6 · Cited by 13
Monitoring a Hypothetical Channelopathy in Chronic Fatigue Syndrome
Nijs, J., Becker, P. D., Demanet, C. J., McGregor, N., Englebienne, P., Verhas, M., & Meirleir, K. D. (2003) · Journal of Chronic Fatigue Syndrome · doi:10.1300/j092v11n01_03 · Cited by 12
Evaluation and treatment of pediatric patients with neurocardiogenic syncope
Sokoloski, M. C. (2001) · Progress in Pediatric Cardiology · doi:10.1016/s1058-9813(01)00095-9 · Cited by 12
MEDICAL THERAPY OF NEUROCARDIOGENIC SYNCOPE
CADMAN, C. S. (2001) · Cardiology Clinics · doi:10.1016/s0733-8651(05)70208-3 · Cited by 12
Current management of syncope: Treatment alternatives
Morillo, C. A., & Baranchuk, A. (2004) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-004-0021-8 · Cited by 11
(2008) · PubMed · Cited by 11
St-Jean, K., Kuś, T., Dupuis, G., Lévesque, K., Thibault, B., Guerra, P. G., Nadeau, R. A., & D’Antono, B. (2008) · Applied Research in Quality of Life · doi:10.1007/s11482-009-9058-x · Cited by 12
Neurocardiogenic syncope: latest pharmacological therapies
Chen, L. Y., & Shen, W.-K. (2006) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.7.9.1151 · Cited by 12
Vasovagal syncope: an update on the latest pharmacological therapies
Schleifer, J. W., & Shen, W.-K. (2014) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.996129 · Cited by 10
Current treatment of recurrent vasovagal syncope: between evidence-based therapy and common sense
Alboni, P., Dinelli, M., Gianfranchi, L., & Pacchioni, F. (2007) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0b013e3280122d50 · Cited by 10
Treatment of Neurocardiogenic Syncope: From Conservative to Cutting-edge
Gampa, A., & Upadhyay, G. A. (2018) · Journal of Innovations in Cardiac Rhythm Management · doi:10.19102/icrm.2018.090702 · Cited by 10
Kabir, M., & Chelimsky, T. C. (2019) · Handbook of clinical neurology · doi:10.1016/b978-0-444-64142-7.00064-3 · Cited by 9
Lee, R., & ELDER, A. T. (2012) · Medicine · doi:10.1016/j.mpmed.2012.10.008 · Cited by 9
Midodrine, an alternative to intravenous vasopressor therapy after spinal surgery
OʼDonnell, B. D., & Synnott, A. (2002) · European Journal of Anaesthesiology · doi:10.1017/s0265021502251352 · Cited by 9
Strategy for the Management of Vasovagal Syncope
Bloomfield, D. M. (2002) · Drugs & Aging · doi:10.2165/00002512-200219030-00003 · Cited by 9
Guía de práctica clínica para el diagnóstico y manejo del síncope (versión 2009)
Moya‐Mitjans, À., Sutton, R., Ammirati, F., Blanc, J., Brignole, M., Dahm, J. B., Deharo, J., Gajek, J. J., Gjesdal, K., Krahn, A. D., et al. (2009) · Revista Española de Cardiología · doi:10.1016/s0300-8932(09)73132-x · Cited by 23
Self-citationPsychological Factors Associated with a Better Quality of Life Following Head-Up Tilt Testing
Lévesque, K., Kuś, T., St-Jean, K., Dupuis, G., Thibault, B., Guerra, P. G., Bédard, F., & D’Antono, B. (2010) · Applied Research in Quality of Life · doi:10.1007/s11482-010-9104-8 · Cited by 8
Trim, G., Krahn, A. D., Klein, G. J., Skanes, A. C., & Yee, R. K. (2003) · Cardiac Electrophysiology Review · doi:10.1023/b:cepr.0000023168.26698.1e · Cited by 8
Chiral investigation of midodrine, a long‐acting α‐adrenergic stimulating agent
Quaglia, M. G., Farina, A., Palmery, M., Desideri, N., Donati, E., Bossù, E., & Strano, S. (2004) · Chirality · doi:10.1002/chir.20041 · Cited by 8
Prevalence of family history in patients with reflex syncope
Holmegard, H. N., Benn, M., Kaijer, M., Haunsø, S., & Mehlsen, J. (2013) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2012.03.054 · Cited by 7
Management of syncope in pediatric patients
Batra, A. S., & Balaji, S. (2005) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-005-0023-1 · Cited by 7
Ongoing Clinical Trials for Vasovagal Syncope: Where are we in 2014?
Coffin, S. T., & Raj, S. R. (2014) · Autonomic Neuroscience · doi:10.1016/j.autneu.2014.05.009 · Cited by 7
Recurrent Syncope in a Cancer Patient: A Case Report and Review of the Literature
Sharma, J., & DOUGHERTY, A. H. (2011) · Cardiology Research and Practice · doi:10.4061/2011/678237 · Cited by 7
Lee, R., & ELDER, A. T. (2016) · Medicine · doi:10.1016/j.mpmed.2016.10.009 · Cited by 7
Midodrine, Adrenergic Agonists and Antagonists
Gilden, J. L. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-386525-0.00130-x · Cited by 7
Role of pacemakers in treating neurocardiogenic syncope
Raj, S. R., & Sheldon, R. S. (2003) · Current Opinion in Cardiology · doi:10.1097/00001573-200301000-00007 · Cited by 7
Melby, D. P., Cytron, J. A., & Benditt, D. G. (2004) · Current Cardiology Reports · doi:10.1007/s11886-004-0042-7 · Cited by 7
Emerging Indications for Cardiac Pacing
Slotwiner, D. J., Steín, K. M., Markowitz, S. M., Mittal, S., Iwai, S., Das, M. K., & Lerman, B. B. (2001) · Heart Disease · doi:10.1097/00132580-200107000-00004 · Cited by 7
Venugopal, D., Jhanjee, R., & Benditt, D. G. (2007) · American Journal of Cardiovascular Drugs · doi:10.2165/00129784-200707060-00003 · Cited by 6
Blue, J. G., & Pecci, M. (2002) · Orthopedic Clinics of North America · doi:10.1016/s0030-5898(02)00008-1 · Cited by 6
Aminorroaya, A., Tavolinejad, H., Sadeghian, S., Jalali, A., Alaeddini, F., Emkanjoo, Z., Mollazadeh, R., Bozorgi, A., Oraii, S., Kiarsi, M., et al. (2021) · American Heart Journal · doi:10.1016/j.ahj.2021.03.002 · Cited by 6
Angaran, P., Klein, G. J., Yee, R. K., Skanes, A. C., Gula, L. J., Leong‐Sit, P., & Krahn, A. D. (2011) · Neurologic Clinics · doi:10.1016/j.ncl.2011.07.005 · Cited by 6
Orthostatic Hypotension and Supine Hypertension in the Patient with Autonomic Failure
Lamarre-Cliché, M. (2014) · Canadian Journal of General Internal Medicine · doi:10.19144/1911-1606.9.3.2 · Cited by 6
Haemodynamic effects of fludrocortisone and midodrine in patients with symptoms due to hypotension
de Lange, F. J., van Zanten, S., Rivasi, G., Groppelli, A., Russo, V., Maggi, R., Capacci, M., Nawaz, S., Comune, A., Ungar, A., et al. (2024) · Clinical Autonomic Research · doi:10.1007/s10286-024-01096-3 · Cited by 5
Brignole, M., Menozzi, C., Rosso, A., Costa, S., Gaggioli, G., Solano, A., Bottoni, N., Bartoli, P., & Sutton, R. (2000) · Springer eBooks · doi:10.1007/978-88-470-2139-6_61 · Cited by 5
Anti-hypotensive effect of “Yahom Navakot” in rats with orthostatic hypotension
Inchan, A., Pathomwichaiwat, T., Bualeong, T., tipratchadaporn, S., & Chootip, K. (2021) · Journal of Traditional and Complementary Medicine · doi:10.1016/j.jtcme.2021.08.002 · Cited by 4
Asai, Y., Sato, T., Kito, D., Yamamoto, T., Hioki, I., Urata, Y., & Abe, Y. (2021) · Journal of Pharmaceutical Health Care and Sciences · doi:10.1186/s40780-021-00193-z · Cited by 4
Vezzosi, T., Domenech, O., Cipollini, C., Cantile, C., Côté, É., & Tognetti, R. (2019) · Journal of the American Veterinary Medical Association · doi:10.2460/javma.255.11.1234 · Cited by 4
Syncope and orthostatic intolerance for the primary care physician
Weimer, L. H. (2004) · Primary Care Clinics in Office Practice · doi:10.1016/s0095-4543(03)00122-2 · Cited by 4
Golovina, G., Duplyakov, D. V., & Dispensary, S. R. C. (2018) · Kardiologiia · doi:10.18087/cardio.2018.8.10151 · Cited by 4
Grubb, B. P., & Karabin, B. L. (2014) · Encyclopedia of the Neurological Sciences · doi:10.1016/b978-0-12-385157-4.01164-7 · Cited by 4
Neurocardiogenic Syncope: Mechanisms, Evaluation and Treatment
Eltahawy, E. A., & Grubb, B. P. (2006) · Future Cardiology · doi:10.2217/14796678.2.3.325 · Cited by 3
Sekar, A., Datta, D., Lakha, A., Jena, S. S., Bansal, S., & Sahu, R. N. (2023) · Asian Journal of Neurosurgery · doi:10.1055/s-0043-1769755 · Cited by 3
Treatment of Vasovagal Syncope: An Update
Armaganijan, L., & Morillo, C. A. (2010) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-010-0087-4 · Cited by 3
Neurovegetative Regulation of the Vascular System
Grubb, B. P., KOSINSKI, D. J., & Kanjwal, Y. (2002) · Springer eBooks · doi:10.1007/978-3-642-56225-9_10 · Cited by 3
Ray, J. C., Kusumoto, F. M., & Goldschlager, N. (2014) · Journal of Intensive Care Medicine · doi:10.1177/0885066614552988 · Cited by 3
Cardiovascular System in Space
Ramsdell, C. D., & Cohen, R. J. (2003) · Encyclopedia of Space Science and Technology · doi:10.1002/0471263869.sst074 · Cited by 2
Mhanna, M., Beran, A., Mhanna, A. S., Al‐Abdouh, A., Jabri, A., Numan, M. J., Alsaiqali, M., Musallam, R., Zerihun, K., & Mahmood, A. (2022) · American Journal of Therapeutics · doi:10.1097/mjt.0000000000001513 · Cited by 2
Midodrine in Pregnancy: A Case Report and Literature Review
Al-Ghamdi, B. S. (2015) · Cardiovascular Pharmacology Open Access · doi:10.4172/2329-6607.1000144 · Cited by 2
Певзнер, А. В., Kuchinskaya, Е. А., Киктев, В. Г., & Хеймец, Г. И. (2021) · Rational Pharmacotherapy in Cardiology · doi:10.20996/1819-6446-2021-04-09 · Cited by 2
Kurbaan, A. S., & Sutton, R. (1999) · Heart · doi:10.1136/hrt.82.6.649 · Cited by 2
Evaluation and Management of Syncope
Grubb, B. P., & KOSINSKI, D. J. (2002) · Contemporary cardiology · doi:10.1007/978-1-59259-090-2_10 · Cited by 2
Orthostatic Hypotension and Vasovagal Syncope
Shaw, B. H., Ng, J., & Raj, S. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809657-4.99798-9 · Cited by 2
Midodrine exposure trends and outcomes reported to United States poison centers: 2000–2023
Kuai, D., Nogee, D., Kieszak, S. M., Geller, A. I., Yeh, M., & Schnall, A. H. (2025) · Clinical Toxicology · doi:10.1080/15563650.2025.2546073 · Cited by 1
Progress in the pharmacological management of vasovagal syncope
Giambusso, V. G., Rafanelli, M., & Sheldon, R. S. (2025) · Expert Review of Clinical Pharmacology · doi:10.1080/17512433.2025.2596875 · Cited by 1
The Management of Vasovagal Syncope in a Patient with Brugada Syndrome
Rhodes, T. E., & Weiss, R. (2012) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2012.03.001 · Cited by 1
Fisher, J. D. (2011) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-011-9579-8 · Cited by 1
Sutton, R. (2013) · Journal of Medical Diagnostic Methods · doi:10.4172/2168-9784.1000139 · Cited by 1
Pacing in Neurally Mediated Syncope Syndromes
Berecki-Gisolf, J., & Sheldon, R. S. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-1616-0.00015-1 · Cited by 1
OBSOLETE: Orthostatic Hypotension and Vasovagal Syncope
Raj, S. R. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.99798-8 · Cited by 1
Kasperowicz, A., Banach, M., Maciejewski, M., & Bielecka-Dabrowa, A. M. (2019) · Springer eBooks · doi:10.1007/978-3-030-30332-7_3 · Cited by 1
Disautonomía: un problema médico poco conocido
Jaime Bravo, S. (2004) · Bol. Hosp. San Juan de Dios · Cited by 1
Andresen, D. (2014) · Herz · doi:10.1007/s00059-014-4096-z · Cited by 1
Reflex Syncope (Neurally Mediated Syncope)
Brignole, M., & Benditt, D. G. (2010) · Springer eBooks · doi:10.1007/978-0-85729-201-8_11 · Cited by 1
Therapeutic Advances in the Management of Orthostatic Hypotension
Patel, K., Kiszko, K., & Torbati, A. (2018) · American Journal of Therapeutics · doi:10.1097/mjt.0000000000000661 · Cited by 1
Lee, H. E., & Lee, D. W. (2021) · Korean Journal of Pediatrics · doi:10.3345/cep.2021.00052 · Cited by 1
Grubb, B. P., & Karas, B. J. (1999) · Cardiac Electrophysiology Review · doi:10.1023/a:1009966904028 · Cited by 1
Therapie der neurokardiogenen Synkope
Schuchert, A. (2002) · Herzschrittmachertherapie + Elektrophysiologie · doi:10.1007/s00399-002-0339-4 · Cited by 1
Sutton, R. (2007) · Wiley eBooks · doi:10.1002/9780470692639.ch16 · Cited by 1
Eltahawy, E. A., & Grubb, B. P. (2007) · Springer eBooks · doi:10.1007/978-0-387-72763-9_13 · Cited by 1
Synkope und epileptischer Anfall
Becker, A., Noachtar, S., Reithmann, C., Brandt, T. H., & Steinbeck, G. (2005) · Der Internist · doi:10.1007/s00108-005-1475-9 · Cited by 1
[Tilt testing in the diagnosis and treatment of syncope].
Timóteo, A. T., & Oliveira, M. (2010) · PubMed · Cited by 1
An Update on the Treatment of Vasovagal Syncope
Brignole, M. (2004) · Cited by 1
Advances in the treatment of cardiac rhythm disturbances
Dubin, A. M., & Hare, G. F. V. (1999) · Current Opinion in Pediatrics · doi:10.1097/00008480-199910000-00011 · Cited by 1
Friederich, H.-C., Michaelsen, J., Hesse, C., Schellberg, D., Schwab, M., & Herzog, W. (2004) · Zeitschrift für Kardiologie · doi:10.1007/s00392-004-0074-4 · Cited by 1
Coping with syncope: tilt towards pacing.
Vk, B., & Sharma, G. (2001) · PubMed · Cited by 1
Grubb, B. P., Kanjwal, Y., & KOSINSKI, D. J. (2003) · Encyclopedia of the Neurological Sciences · doi:10.1016/b0-12-226870-9/01349-6 · Cited by 1
Kreislaufregulationsstörungen/Synkope (S2)
WILL, J. C., & SCHRANZ, D. (2007) · Elsevier eBooks · doi:10.1016/b978-343722398-3.50007-7
Head-Up Tilt Testing for Neurocardiogenic Syncope
Bhatia, A., & Sra, J. S. (2000) · Cardiac Electrophysiology Review · doi:10.1023/a:1009918631164
Treatment of Vasovagal Syncope: Counseling, Drugs, and Counter-Pressure Maneuvers
Ammirati, F., Danisi, N., & Romano, M. (2014) · Springer eBooks · doi:10.1007/978-3-319-09102-0_19
Drugs for the Prevention and Control of Syncope
Barbey, J. T. (1998) · Cardiac Electrophysiology Review · doi:10.1023/a:1009900705224
Diagnosis and Acute Management of Patients with Symptomatic Bradyarrhythmias
Sung, R. J., & Lauer, M. R. (2000) · Springer eBooks · doi:10.1007/978-94-011-4371-4_7
Evaluation and Management of Syncope
Bindra, P. S., Marchlinski, F. E., & Lin, D. (2008) · Clinical Medicine Insights Circulatory Respiratory and Pulmonary Medicine · doi:10.4137/ccrpm.s490
Selektive Hemmung der Noradrenalin-Wiederaufnahme als humanes Modell für orthostatische Intoleranz
Schröder, C. (2003) · edoc Publication server (Humboldt University of Berlin) · doi:10.18452/14846
Drugs and pacemakers for neurally mediated reflex syncope
Romme, J. J. C. M., Black, C. N., Colman, N., Scholten, R. J. P. M., Reitsma, J. B., Wieling, W., & van Dijk, N. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004194.pub2
Drugs that affect autonomic functions or the extrapyramidal system
Schächter, M. (2010) · Side effects of drugs annual · doi:10.1016/s0378-6080(10)32013-7
Síncope. Nuevos conceptos clínicos
Marcos, J. O., Hernández‐Madrid, A., & Serrano, C. M. (2001) · Medicine - Programa de Formación Médica Continuada Acreditado · doi:10.1016/s0304-5412(01)70409-x
Neurologic Presentations of Cardiac Disease
Kelley, R. E. (2009) · Neurologic Clinics · doi:10.1016/j.ncl.2009.09.014
Neurally-mediated reflex syncope: diagnosis and treatment
Romme, J. J. C. M. (2010) · UvA-DARE (University of Amsterdam)
Midodrine for Treatment of Vasovagal Syncope
Benditt, D. G., Wilbert, L. A., Fahy, G. J., Sakaguchi, S., Lurie, K. G., & Samniah, N. (2000) · Springer eBooks · doi:10.1007/978-88-470-2139-6_62
Metadata
- Authors
- Ward, C. R., Gray, J. C., Gilroy, J. J., & Kenny, R. A.
- Affiliations
- Royal Victoria Infirmary (GB)
- Corresponding author
- Kenny, R A
- ORCID
- Kenny, R A
- Venue
- Heart
- Publisher
- BMJ
- Published
- 1998-01-01
- Volume
- 79
- Issue
- 1
- Pages
- 45-49
- ISSN
- 1355-6037 (ISSN-L)
- 1468-201X
- PMC
- PMC1728578
- OpenAlex
- W2120769605
- Semantic Scholar
- 8c8b308da301fd99036cd9943d91f93c05304560
- Cited by
- 249
- References
- 34
- Citations by year
- 2025: 4 · 2024: 2 · 2023: 1 · 2022: 4 · 2021: 10 · 2020: 1 · 2019: 4 · 2018: 4 · 2017: 9 · 2016: 7 · 2015: 5 · 2014: 15 · 2013: 7 · 2012: 9
- FWCI
- 16.68
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Heart (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Neurology › Vestibular and auditory disorders
- Keywords
- midodrine, vasovagal syncope, orthostatic intolerance, alpha-adrenergic agonists, head-up tilt, nitroglycerin, symptom frequency, quality of life, venous return, blood pressure, heart rate, adverse effects, treatment response assessment
- MeSH terms
- Adrenergic alpha-Agonists, Blood Pressure, Cardiography, Impedance, Double-Blind Method, Female, Heart Rate, Humans, Male, Middle Aged, Midodrine, Cross-Over Studies, Tilt-Table Test, Syncope, Vasovagal
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