Cited by 217Atrial Fibrillation Management and OutcomesBlood Coagulation and Thrombosis MechanismsBlood transfusion and management

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Warfarin reversal

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Hanley, J P·2004·Journal of Clinical Pathology

DOI 10.1136/jcp.2003.008904PMC PMC1770479

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Abstract

Warfarin is the most commonly used oral anticoagulant in the UK. It is associated with few side effects apart from haemorrhage. The most appropriate way to reverse the anticoagulant effect of warfarin depends on the clinical circumstances. In serious bleeding, rapid reversal is required, whereas in minor bleeding or asymptomatic over anticoagulation, a more leisurely approach is usually appropriate. This review discusses the current approaches to warfarin reversal in clinical practice. The development of a uniform approach to warfarin reversal in the Northern Region is described.

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Authors: Hanley, J. P.
Affiliations: Royal Victoria Infirmary (GB)
Corresponding author: Hanley, J P
ORCID: Hanley, J P
Venue: Journal of Clinical Pathology
Publisher: BMJ
Published: 2004-10-27
Volume: 57
Issue: 11
Pages: 1132-1139
ISSN: 0021-9746 (ISSN-L)
1472-4146
DOI: 10.1136/jcp.2003.008904
PMC: PMC1770479
OpenAlex: W4237953286
Cited by: 215
References: 76
Citations by year: 2026: 2 · 2025: 4 · 2024: 7 · 2023: 6 · 2022: 7 · 2021: 10 · 2020: 9 · 2019: 4 · 2018: 7 · 2017: 12 · 2016: 14 · 2015: 14 · 2014: 6 · 2013: 16 · 2012: 11
FWCI: 1.39
Type: journal article
Language: en
Open access: bronze
doi.org
Locations: Journal of Clinical Pathology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
Newcastle University ePrints (Newcastle Univesity)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
Health Sciences › Medicine › Hematology › Blood Coagulation and Thrombosis Mechanisms
Health Sciences › Medicine › Hematology › Blood transfusion and management
Keywords: warfarin reversal, oral anticoagulants, anticoagulant reversal, hemorrhage, overanticoagulation, northern regions
MeSH terms: Administration, Oral, Anticoagulants, Blood Coagulation, Blood Coagulation Factors, Child, Coagulants, Drug Administration Schedule, Factor VII, Hemorrhage, Humans, Plasma, Recombinant Proteins, Vitamin K, Warfarin, Factor VIIa, Practice Guidelines as Topic, Intracranial Hemorrhages

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