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Cited by 481

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Fatigue syndromes: a comparison of chronic "postviral" fatigue with neuromuscular and affective disorders.

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Wessely, S, Powell, R·1989·Journal of Neurology, Neurosurgery & Psychiatry

Abstract

Patients (n = 47) presenting to a neurological centre with unexplained chronic "postviral" fatigue (CFS) were studied prospectively. Controls were patients with peripheral fatiguing neuromuscular diseases and inpatients with major depression in a psychiatric hospital. Seventy-two percent of the CFS patients were cases of psychiatric disorder, using criteria that excluded fatigue as a symptom, compared with 36% of the neuromuscular group. There was no difference in subjective complaints of physical fatigue between all groups. Mental fatigue and fatigability was equally common in CFS and affective patients, but only occurred in those neuromuscular patients who were also cases of psychiatric disorder. Overall, the CFS patients more closely resembled the affective than the neuromuscular patients. Attribution of symptoms to physical rather than psychological causes was the principal difference between matched CFS and psychiatric controls. The symptoms of "postviral" fatigue had little ability to discriminate between CFS and affective disorder. The fatigue in CFS appeared central in origin, suggesting it is not primarily a neuromuscular illness. The implications for research and treatment of chronic fatigue are discussed.

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Metadata

Authors
Wessely, S., & Powell, R.
Venue
Journal of Neurology, Neurosurgery & Psychiatry
Publisher
BMJ
Published
1989-08-01
Volume
52
Issue
8
Pages
940-948
ISSN
0022-3050 (ISSN-L)
OpenAlex
W2036393776
Cited by
481
References
4
FWCI
25.20
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Fatigue syndromes: a comparison of chronic "postviral" fatigue with neuromuscular and affective disorders. https://app.cochat.ai/papers/10.1136/jnnp.52.8.940
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Wessely, S., & Powell, R. (1989). Fatigue syndromes: a comparison of chronic "postviral" fatigue with neuromuscular and affective disorders. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.52.8.940

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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