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Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients.
Open accessAbstract
The clinical and electrophysiological features were prospectively studied of 75 patients (46 men and 29 women) with chronic polyneuropathy presenting in middle or old age in whom a diagnosis could not be made even after extensive evaluation and a follow up of six months. The mean age at the onset of symptoms was 56.5 years. The clinical features of chronic idiopathic polyneuropathy are heterogeneous. On clinical grounds 44 patients had a sensorimotor, 29 patients a sensory, and two patients a motor polyneuropathy. The overall clinical course in chronic idiopathic polyneuropathy was slowly progressive. None of the patients became severely disabled. Electrophysiological and nerve biopsy studies were compatible with an axonal polyneuropathy. Antibodies against myelin associated glycoprotein, gangliosides, and sulphatides were assessed in 70 patients and found to be negative.
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Cites
Interobserver agreement for the assessment of handicap in stroke patients
van Swieten, J. C., Koudstaal, P. J., Visser, M. C., Schouten, H. J., & van Gijn, J. (1988) · Stroke · doi:10.1161/01.str.19.5.604 · Cited by 6,512
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Duyff, R. F. (2000) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp.68.6.750 · Cited by 447
Clinicopathologic findings and prognosis of chronic inflammatory demyelinating polyneuropathy
Bouchard, C., Lacroix, C., Planté, V., Adams, D., Chedru, F., Guglielmi, J.-M., & Said, G. (1999) · Neurology · doi:10.1212/wnl.52.3.498 · Cited by 294
The epidemiology and risk factors of chronic polyneuropathy
Hanewinckel, R., van Oijen, M., Ikram, M. A., & van Doorn, P. A. (2016) · European Journal of Epidemiology · doi:10.1007/s10654-015-0094-6 · Cited by 293
Idiopathic polyneuropathy and impaired glucose metabolism in a Norwegian patient series
Nebuchennykh, M., Løseth, S., Jorde, R., & Mellgren, S. I. (2008) · European Journal of Neurology · doi:10.1111/j.1468-1331.2008.02197.x · Cited by 49
Metadata
- Authors
- Notermans, N. C., Wokke, J. H., Franssen, H., van der Graaf, Y., Vermeulen, M., van den Berg, L. H., Bar, P. R., & Jennekens, F. G.
- Venue
- Journal of Neurology, Neurosurgery & Psychiatry
- Publisher
- BMJ
- Published
- 1993-10-01
- Volume
- 56
- Issue
- 10
- Pages
- 1066-1071
- ISSN
- 0022-3050 (ISSN-L)
- OpenAlex
- W2112821184
- Cited by
- 174
- References
- 1
- FWCI
- 2.58
- Type
- journal article
- Language
- en
- Open access
- bronze
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- CoChat. (2026). Citation check: Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients. https://app.cochat.ai/papers/10.1136/jnnp.56.10.1066
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- Notermans, N. C., Wokke, J. H., Franssen, H., van der Graaf, Y., Vermeulen, M., van den Berg, L. H., Bar, P. R., & Jennekens, F. G. (1993). Chronic idiopathic polyneuropathy presenting in middle or old age: a clinical and electrophysiological study of 75 patients. Journal of Neurology, Neurosurgery & Psychiatry. https://doi.org/10.1136/jnnp.56.10.1066
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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