The DOI matches its Crossref record; 32 of the 32 references it cites were found in a registry or an index.
The effect of high temperatures on cause-specific mortality in England and Wales
Abstract
Objectives: Several observational studies have suggested an association between high temperatures and all-cause mortality. However, estimates on more specific mortality outcomes are sparse, and frequently assessed in studies using different analytical methods. Methods: A time series analysis was performed on 10 regions in England and Wales during the summers (June–September) of 1993–2006. Average percentage linear increases in risk for a 1°C increase in temperature above region-specific thresholds and attributable deaths were computed by cause-specific mortality and age groups (0–64, 65–74, 75–84, 85+). Results: There was evidence of increased mortality with heat for almost all cause-of-death groups examined, with an overall increase in all-cause mortality of 2.1% (95% CI 1.6% to 2.6%) for a 1°C rise above the regional heat threshold. Among main causes, the steepest increase in risk was for respiratory mortality (+4.1% (3.5% to 4.8%) per 1°C). It was much smaller for cardiovascular causes (+1.8% (1.2% to 2.5%)) and myocardial infarction (+1.1% (0.7% to 1.5%)), but comparatively high for arrhythmias (+5.0% (3.2% to 6.9%)) and pulmonary heart disease (+8.3% (2.7% to 14.3%)). Among non- cardiorespiratory causes, the strongest effects were for genitourinary (+3.8% (2.9% to 4.7%)) and nervous system (+4.6% (3.7% to 5.4%)) disorders. 33.9% of heat deaths were attributable to cardiovascular causes, 24.7% to respiratory causes and 41.3% to all other causes combined. Conclusions: These results suggest that the risk of heat-related mortality is distributed across a wide range of different causes, and that targeting of preventative actions based on pre-existing disease is unlikely to be efficient.
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Cites
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Cited by
Mortality risk attributable to high and low ambient temperature: a multicountry observational study
Gasparrini, A., Guo, Y., Hashizume, M., Lavigne, E., Zanobetti, A., Schwartz, J., Tobias, A., Tong, S., Rocklöv, J., Forsberg, B., et al. (2015) · The Lancet · doi:10.1016/s0140-6736(14)62114-0 · Cited by 2,965
Self-citationReducing and meta-analysing estimates from distributed lag non-linear models
Gasparrini, A., & Armstrong, B. (2013) · BMC Medical Research Methodology · doi:10.1186/1471-2288-13-1 · Cited by 1,081
Self-citationTemporal Variation in Heat–Mortality Associations: A Multicountry Study
Gasparrini, A., Guo, Y., Hashizume, M., Kinney, P. L., Petkova, E. P., Lavigne, E., Zanobetti, A., Schwartz, J. D., Tobias, A., Leone, M., et al. (2015) · Environmental Health Perspectives · doi:10.1289/ehp.1409070 · Cited by 470
Self-citationLiu, J., Varghese, B. M., Hansen, A., Xiang, J., Zhang, Y., Dear, K., Gourley, M., Driscoll, T., Morgan, G., Capon, A., et al. (2021) · Environment International · doi:10.1016/j.envint.2021.106533 · Cited by 406
Cardiovascular response to thermoregulatory challenges
Liu, C., Yavar, Z., & Sun, Q. (2015) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00199.2015 · Cited by 363
Metadata
- Authors
- Gasparrini, A., Armstrong, B., Kovats, S., & Wilkinson, P.
- Venue
- Occupational and Environmental Medicine
- Publisher
- BMJ
- Published
- 2011-03-09
- Volume
- 69
- Issue
- 1
- Pages
- 56-61
- ISSN
- 0007-1072 (ISSN-L)
- 1351-0711
- 1470-7926
- OpenAlex
- W1972714338
- Cited by
- 271
- References
- 32
- FWCI
- 6.65
- Type
- journal article
- Language
- en
- Open access
- closed
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