The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
Study of occupation and amyotrophic lateral sclerosis in a Danish cohort
Abstract
Objectives: Several manuscripts have proposed associations between amyotrophic lateral sclerosis (ALS) and occupational toxicant exposures—not to mention physical activity and trauma/injury. Some have also reported associations in investigations of specific occupations. Using data from a prospective Danish cohort study, we investigated the association between employment in certain industries and ALS diagnosis. Methods: We identified 1826 ALS cases who were 25 years old or less in 1964 and diagnosed from 1982 to 2013 from the Danish National Patient Registry then matched 100 population controls to each case based on birth year and sex. Demographic data were linked to the Danish Pension Fund to determine occupation history. Conditional logistic regression models were adjusted for socioeconomic status, marital status and residential location at the index date. Results: There was an increase in odds of ALS among men who worked in agriculture, hunting, forestry or fishing (adjusted OR (aOR)=1.21; 95% CI 1.02 to 1.45). There was also a positive association for men employed in construction (aOR=1.21; 95% CI 1.05 to 1.39). In women, a protective association was seen with employment in the cleaning industry (aOR=0.69; 95% CI 0.52 to 0.93). Conclusions: Our study shows various occupations with exposure to toxicants, such as diesel exhaust and lead, and strenuous physical activity associated with increased odds of ALS in men. Future studies should have a particular focus on gathering detailed information on physical exertion and toxicant exposures specific to certain job tasks.
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“Other studies have reported a higher risk of ALS for construction workers, both in New England 1993‐1996 (OR = 2.9, 95% CI 1.2‐7.2), and in Denmark 1982‐2013 (OR 1.21, 95% CI 1.05‐1.39).”
From Risk factors for amyotrophic lateral sclerosis: A regional United States case‐control study (2021) · cites this paper as [43]
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The Danish National Patient Registry: a review of content, data quality, and research potential
Schmidt, M., Schmidt, S. A. J., Sandegaard, J. L., Ehrenstein, V., Pedersen, L., & Sørensen, H. T. (2015) · Clinical Epidemiology · doi:10.2147/clep.s91125 · Cited by 4,769
The Danish Civil Registration System. A cohort of eight million persons.
Pedersen, C. B., Gøtzsche, H., Møller, J. O., & Mortensen, P. B. (2006) · PubMed · Cited by 1,617
van Es, M. A., Hardiman, O., Chio, A., Al-Chalabi, A., Pasterkamp, R. J., Veldink, J. H., & van den Berg, L. H. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31287-4 · Cited by 1,298
Occupation and cancer – follow-up of 15 million people in five Nordic countries
Pukkala, E., Martinsen, J. I., Lynge, E., Gunnarsdottir, H. K., Sparén, P., Tryggvadottir, L., Weiderpass, E., & Kjaerheim, K. (2009) · Acta Oncologica · doi:10.1080/02841860902913546 · Cited by 718
Mitchell, J., & Borasio, G. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60944-1 · Cited by 561
Diesel and gasoline engine exhausts and some nitroarenes.
(1989) · PubMed Central · Cited by 399
Levesque, S., Taetzsch, T., Lull, M. E., Kodavanti, U., Stadler, K., Wagner, A., Johnson, J. A., Duke, L., Kodavanti, P., Surace, M. J., et al. (2011) · Environmental Health Perspectives · doi:10.1289/ehp.1002986 · Cited by 371
Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis
D’Amico, E., Factor-Litvak, P., Santella, R. M., & Mitsumoto, H. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.06.029 · Cited by 321
Wang, M.-D., Little, J., Gomes, J., Cashman, N. R., & Krewski, D. (2017) · NeuroToxicology · doi:10.1016/j.neuro.2016.06.015 · Cited by 233
Pesticide exposure and amyotrophic lateral sclerosis
Kamel, F., Umbach, D. M., Bedlack, R., Richards, M., Watson, M. L., Alavanja, M. C. R., Blair, A. E., Hoppin, J. A., Schmidt, S., & Sandler, D. P. (2012) · NeuroToxicology · doi:10.1016/j.neuro.2012.04.001 · Cited by 173
Cited by
Epidemiology of amyotrophic lateral sclerosis: an update of recent literature
Longinetti, E., & Fang, F. (2019) · Current Opinion in Neurology · doi:10.1097/wco.0000000000000730 · Cited by 620
Risk factors for amyotrophic lateral sclerosis: A regional United States case‐control study
Andrew, A. S., Bradley, W. G., Peipert, D., Butt, T., Amoako, K., Pioro, E. P., Tandan, R., Novak, J., Quick, A., Pugar, K. D., et al. (2021) · Muscle & Nerve · doi:10.1002/mus.27085 · Cited by 54
Military service and related risk factors for amyotrophic lateral sclerosis
McKay, K. A., Smith, K. A., Smertinaite, L., Fang, F., Ingre, C., & Taube, F. (2021) · Acta Neurologica Scandinavica · doi:10.1111/ane.13345 · Cited by 50
Beaudin, M., Salachas, F., Pradat, P.-F., & Dupré, N. (2022) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · doi:10.1080/21678421.2022.2028167 · Cited by 12
Metadata
- Authors
- Dickerson, A. S., Hansen, J., Kioumourtzoglou, M.-A., Specht, A. J., Gredal, O., & Weisskopf, M. G.
- ORCID
- Dickerson, Aisha S
- Venue
- Occupational and Environmental Medicine
- Publisher
- BMJ
- Published
- 2018-06-25
- Volume
- 75
- Issue
- 9
- Pages
- 630-638
- ISSN
- 1351-0711
- 1470-7926
- PMC
- PMC6445390
- Cited by
- 40
- References
- 38
- Language
- en
- Funders
- National Institute of Environmental Health Sciences
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