The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Acute disseminated encephalomyelitis
Open accessAbstract
Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system, and is characterised by multifocal white matter involvement. Diffuse neurological signs along with multifocal lesions in brain and spinal cord characterise the disease. Possibly, a T cell mediated autoimmune response to myelin basic protein, triggered by an infection or vaccination, underlies its pathogenesis. ADEM is a monophasic illness with favourable long term prognosis. The differentiation of ADEM from a first attack of multiple sclerosis has prognostic and therapeutic implications; this distinction is often difficult. Most patients with ADEM improve with methylprednisolone. If that fails immunoglobulins, plasmapheresis, or cytotoxic drugs can be given. Recent literature suggests that a significant proportion of patients with ADEM will later develop multiple sclerosis; however, follow up experience from developing countries does not support this view.
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Citations
Cites
Animal models for autoimmune demyelinating disorders of the nervous system
Gold, R., Hartung, H.-P., & Toyka, K. V. (2000) · Molecular Medicine Today · doi:10.1016/s1357-4310(99)01639-1 · Cited by 292
Cited by
Szczepiorkowski, Z. M., Winters, J. L., Bandarenko, N., Kim, H. C., Linenberger, M. L., Marques, M. B., Sarode, R., Schwartz, J., Weinstein, R., & Shaz, B. H. (2010) · Journal of Clinical Apheresis · doi:10.1002/jca.20240 · Cited by 508
The Role of Plasmapheresis in Critical Illness
Nguyen, T. C., Kiss, J. E., Goldman, J. R., & Carcillo, J. A. (2012) · Critical Care Clinics · doi:10.1016/j.ccc.2012.04.009 · Cited by 83
Acute disseminated encephalomyelitis (ADEM) following recent Oxford/AstraZeneca COVID-19 vaccination
Permezel, F., Borojevic, B., Lau, S., & de Boer, H. H. (2022) · Forensic Science, Medicine and Pathology · doi:10.1007/s12024-021-00440-7 · Cited by 62
Brock, K., Reyes, S. C., Conner, C., Gillson, N., Weiss, M., Elfituri, O., & Paydar, A. (2023) · BJR|case reports · doi:10.1259/bjrcr.20220097 · Cited by 6
Metadata
- Authors
- Garg, R. K.
- Venue
- Postgraduate Medical Journal
- Publisher
- Oxford University Press (OUP)
- Published
- 2003-01-01
- Volume
- 79
- Issue
- 927
- Pages
- 11-17
- ISSN
- 0032-5473 (ISSN-L)
- 1469-0756
- OpenAlex
- W4252387530
- Cited by
- 221
- References
- 1
- FWCI
- 4.99
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
