Condom effectiveness against non-viral sexually transmitted infections: a prospective study using electronic daily diaries.
Open accessAbstract
Objectives: To prospectively evaluate the protective value of consistent and correct use of latex condoms against the acquisition of Chlamydia trachomatis,Neisseria gonorrhoeae and Trichomonas vaginalis. Methods: Patients (N=929) attending clinics that treat sexually transmitted infections (STIs) were prospectively followed for up to 6 months. Urine STI nucleic acid amplification testing was performed at baseline, 3 months and 6 months. Participants were instructed to respond to daily prompts from a handheld device by completing a report for each penile-vaginal sexual intercourse event. Generalised estimating equation models examined associations of consistent as well as consistent and correct condom use with STI incidence over 3-month intervals. Results: Consistent condom use was not significantly associated with STI incidence (Estimated OR (EOR)=0.75; 95% CI (CI) 0.43 to 1.30; p=0.31). However, individuals who used condoms both correctly and consistently were estimated to have 59% lower odds of acquiring an STI (EOR=0.41; 95% CI 0.19 to 0.90; p=.026), compared to those who did not. Conclusions: The correct as well as the consistent use of condoms greatly reduces the odds of non-viral STI acquisition.
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Studies demonstrate that consistent condom use reduces the risk for other STIs, including chlamydia, gonorrhea, hepatitis B, and trichomoniasis.
“Moreover, studies demonstrate that consistent condom use reduces the risk for other STIs, including chlamydia, gonorrhea, hepatitis B, and trichomoniasis (18–21).”
From Sexually Transmitted Infections Treatment Guidelines, 2021 (2021) · cites this paper as [18]
The Introduction identifies chlamydia, gonorrhea, and trichomoniasis as the STIs studied. The Results (Multivariate Analyses) find reduced odds only with both correct and consistent condom use; consistent use alone was not significantly protective. This paper does not study hepatitis B. (LLM, conf=0.88)
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Cited by
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Sexually Transmitted Infections Treatment Guidelines, 2021
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- Authors
- Crosby, R. A., Charnigo, R. A., Weathers, C., Caliendo, A. M., & Shrier, L. A.
- Affiliations
- University of Kentucky (US)
- Emory University (US)
- Boston Children's Hospital (US)
- Corresponding author
- Crosby, Richard A
- Venue
- Sexually Transmitted Infections
- Publisher
- BMJ
- Published
- 2012-09-21
- Volume
- 88
- Issue
- 7
- Pages
- 484-489
- ISSN
- 0007-134X (ISSN-L)
- 1368-4973
- 1472-3263
- PMC
- PMC3502658
- OpenAlex
- W2158547693
- Cited by
- 98
- References
- 27
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 2 · 2023: 1 · 2022: 10 · 2021: 6 · 2020: 3 · 2019: 5 · 2018: 3 · 2017: 12 · 2016: 13 · 2015: 11 · 2014: 15 · 2013: 4 · 2012: 4
- FWCI
- 9.40
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Sexually Transmitted Infections (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (RA1068119A, 5r01ai068119-05)
- Center for AIDS Research, University of Washington (P30 AI050409)
- National Institute of Allergy and Infectious Diseases (AI-050409, R01 AI068119, P30AI050409)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Health Professions › General Health Professions › Adolescent Sexual and Reproductive Health
- Keywords
- condom use, latex condoms, Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, consistent condom use, electronic diary, penile-vaginal intercourse, STI incidence
- MeSH terms
- Adolescent, Adult, Chlamydia trachomatis, DNA, Bacterial, Female, Follow-Up Studies, Gonorrhea, Humans, Lymphogranuloma Venereum, Male, Neisseria gonorrhoeae, Prospective Studies, Trichomonas Infections, Trichomonas vaginalis, Urine, Incidence, DNA, Protozoan, Condoms, Young Adult
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