Effects of practitioner education, practitioner payment and reimbursement of patients’ drug costs on smoking cessation in primary care: a cluster randomised trial
Open accessAbstract
Objective:To evaluate new strategies to enhance the promotion of smoking cessation in general practice. Design:Cluster randomised trial, 2×2 factorial design. Setting:82 medical practices in Germany, including 94 general practitioners. Participants:577 patients who smoked at least 10 cigarettes per day (irrespective of their intention to stop smoking) and were aged 36–75 years. Interventions:Provision of a 2-h physician group training in smoking cessation methods and direct physician payments for every participant not smoking 12 months after recruitment (TI, training+incentive); provision of the same training and direct participant reimbursements for pharmacy costs associated with nicotine replacement therapy or bupropion treatment (TM, training+medication). Main outcome measure:Self-reported smoking abstinence obtained at 12 months follow-up and validated by serum cotinine. Results:In intention-to-treat analysis, smoking abstinence at 12 months follow-up was 3% (2/74), 3% (5/144), 12% (17/140) and 15% (32/219) in the usual care, and interventions TI, TM and TI+TM, respectively. Applying a mixed logistic regression model, no effect was identified for intervention TI (odds ratio (OR) 1.26, 95% confidence interval (CI) 0.65 to 2.43), but intervention TM strongly increased the odds of cessation (OR 4.77, 95% CI 2.03 to 11.22). Conclusion:Providing cost-free effective drugs to patients along with improved training opportunities for general practitioners could be an effective measure to achieve successful promotion of smoking cessation in general practice.
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A smoking cessation implementation trial examined whether direct patient reimbursement for medication and/or physician group training affected medication use, with patients nested in physicians and all four combinations tested.
“An example of this design is a trial for smoking cessation implementation, testing whether direct patient reimbursement for medication and/or physician group training influence the use of these medications. Patients are nested within physicians, and all four combinations are tested (107).”
From An Overview of Research and Evaluation Designs for Dissemination and Implementation (2017) · cites this paper as [107]
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Cites
The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire
HEATHERTON, T. F., KOZLOWSKI, L. T., FRECKER, R. C., & FAGERSTROM, K. (1991) · British Journal of Addiction · doi:10.1111/j.1360-0443.1991.tb01879.x · Cited by 10,738 · see citing works
Nicotine replacement therapy for smoking cessation
Stead, L. F., Perera, R., Bullen, C., Mant, D., Hartmann‐Boyce, J., Cahill, K., & Lancaster, T. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000146.pub4 · Cited by 2,514 · see citing works
DiClemente, C. C., Prochaska, J. O., Fairhurst, S., Velicer, W. F., Velasquez, M. M., & Rossi, J. S. (1991) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.59.2.295 · Cited by 2,402 · see citing works
DiClemente, C. C., Prochaska, J. O., Fairhurst, S., et al. (1991) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.59.2.295 · Cited by 1,838 · see citing works
Antidepressants for smoking cessation
Howes, S., Hartmann-Boyce, J., Livingstone-Banks, J., Hong, B., & Lindson, N. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000031.pub5 · Cited by 1,352 · see citing works
Outcome criteria in smoking cessation trials: proposal for a common standard
West, R., Hajek, P., Stead, L., & Stapleton, J. (2005) · Addiction · doi:10.1111/j.1360-0443.2004.00995.x · Cited by 1,285 · see citing works
Measures of abstinence in clinical trials: issues and recommendations
Hughes, J. R., Keely, J. P., NIAURA, R. S., Ossip-Klein, D. J., RICHMOND, R. L., & Swan, G. E. (2003) · Nicotine & Tobacco Research · doi:10.1093/ntr/5.1.13 · Cited by 1,058 · see citing works
Nicotine replacement therapy for smoking cessation
Silagy, C., Lancaster, T., Stead, L., Mant, D., & Fowler, G. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000146.pub2 · Cited by 972 · see citing works
Curry, S. J., Grothaus, L. C., McAfee, T. A., & Pabiniak, C. J. (1998) · New England Journal of Medicine · doi:10.1056/nejm199809033391006 · Cited by 314 · see citing works
Training health professionals in smoking cessation
Lancaster, T., & Fowler, G. (2000) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000214 · Cited by 221 · see citing works
Healthcare financing systems for increasing the use of tobacco dependence treatment
van den Brand, F. A., Nagelhout, G. E., Reda, A. A., Winkens, B., Evers, S., Kotz, D., & van Schayck, O. C. P. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004305.pub5 · Cited by 217 · see citing works
Antidepressants for smoking cessation
Hughes, J., Stead, L., & Lancaster, T. (2004) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000031.pub2 · Cited by 172 · see citing works
Hammond, D. G., McDonald, P., Fong, G. T., & Borland, R. (2004) · Addiction · doi:10.1111/j.1360-0443.2004.00754.x · Cited by 171 · see citing works
Twardella, D., & Brenner, H. (2005) · European Journal of Public Health · doi:10.1093/eurpub/cki123 · Cited by 138 · see citing works
Self-citationYoung, J. M., & Ward, J. (2001) · Family Practice · doi:10.1093/fampra/18.1.14 · Cited by 132 · see citing works
Schauffler, H. H., McMenamin, S. B., Olson, K., Boyce-Smith, G., Rideout, J., & Kamil, J. (2001) · Tobacco Control · doi:10.1136/tc.10.2.175 · Cited by 109 · see citing works
Seccareccia, F., Zuccaro, P., Pacifici, R., et al. (2003) · European Journal of Epidemiology · doi:10.1023/a:1024672522802 · Cited by 102 · see citing works
Measures of abstinence in clinical trials: issues and recommendations
Hughes, J. R., & Hughes, J. R. (2003) · Nicotine & Tobacco Research · doi:10.1080/14622200307270 · Cited by 96 · see citing works
General practitioners' perceived barriers to smoking cessation--results from four Nordic countries
Helgason, X. C. S. R., & Lund, K. E. (2002) · Scandinavian Journal of Public Health · doi:10.1080/14034940210133799 · Cited by 92 · see citing works
Coleman, T. J., & Wilson, A. (1996) · PubMed · Cited by 77 · see citing works
Anderson, P., & Jané‐Llopis, E. (2004) · Addiction · doi:10.1111/j.1360-0443.2003.00672.x · Cited by 60 · see citing works
How to use SAS ® for Logistic Regression with Correlated Data
Kuß, O. (2002) · Cited by 53 · see citing works
John, U., Meyer, C., Rumpf, H., & Hapke, U. (2003) · Preventive Medicine · doi:10.1016/s0091-7435(03)00149-x · Cited by 51 · see citing works
(2003) · British Journal of Ophthalmology · doi:10.1136/bjo.87.8.932-a · Cited by 49 · see citing works
Implementing guidelines for smoking cessation
Katz, D. A., Brown, R. B., Muehlenbruch, D. R., et al. (2004) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2004.07.015 · Cited by 44 · see citing works
Coleman, T. J., Wynn, A. T., Barrett, S., et al. (2001) · BMJ · doi:10.1136/bmj.323.7310.435 · Cited by 40 · see citing works
Coleman, T. J., Wynn, A. T., Stevenson, K., et al. (2001) · BMJ · doi:10.1136/bmj.323.7310.432 · Cited by 32 · see citing works
McLeod, D. L., Somasundaram, R., Howden‐Chapman, P., & Dowell, A. C. (2000) · PubMed · Cited by 28 · see citing works
Senore, C. (1999) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(98)00132-2 · Cited by 26 · see citing works
GP prescribing of nicotine replacement and bupropion to aid smoking cessation in England and Wales
McEwen, A., West, R., & Owen, L. (2004) · Addiction · doi:10.1111/j.1360-0443.2004.00876.x · Cited by 21 · see citing works
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Physician advice for smoking cessation
Stead, L. F., Buitrago, D., Preciado, N., Sanchez, G., Hartmann-Boyce, J., & Lancaster, T. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000165.pub4 · Cited by 1,955 · see citing works
The effect of financial incentives on the quality of health care provided by primary care physicians
Scott, A., Sivey, P., Ait Ouakrim, D., Willenberg, L., Naccarella, L., Furler, J., & Young, D. (2011) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd008451.pub2 · Cited by 568 · see citing works
An Overview of Research and Evaluation Designs for Dissemination and Implementation
Brown, C. H., Curran, G., Palinkas, L. A., Aarons, G. A., Wells, K. B., Jones, L., Collins, L. M., Duan, N., Mittman, B. S., Wallace, A., et al. (2017) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-031816-044215 · Cited by 509 · see citing works
Physician advice for smoking cessation
Stead, L. F., Bergson, G., & Lancaster, T. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000165.pub3 · Cited by 445 · see citing works
A cluster-randomized effectiveness trial of smoking cessation modified for at-risk smoker subgroups
Batra, A., Collins, S. E., Schröter, M., Eck, S., Torchalla, I., & Buchkremer, G. (2010) · Journal of Substance Abuse Treatment · doi:10.1016/j.jsat.2009.08.003 · Cited by 31 · see citing works
- Authors
- Twardella, D., & Brenner, H.
- Affiliations
- Heidelberg University (DE)
- Corresponding author
- Brenner, Hermann
- ORCID
- Brenner, Hermann
- Venue
- Tobacco Control
- Publisher
- BMJ
- Published
- 2007-02
- Volume
- 16
- Issue
- 1
- Pages
- 15-21
- ISSN
- 0964-4563 (ISSN-L)
- 1468-3318
- PMC
- PMC2598437
- OpenAlex
- W1977122622
- Cited by
- 84
- References
- 30
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 3 · 2019: 3 · 2018: 4 · 2017: 4 · 2016: 2 · 2015: 4 · 2014: 8 · 2013: 8 · 2012: 6
- FWCI
- 5.56
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Tobacco Control (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Health Professions › General Health Professions › Primary Care and Health Outcomes
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Keywords
- smoking cessation, general practitioners, physician training, financial incentives, nicotine replacement therapy, bupropion, smoking abstinence, primary care, tobacco dependence treatment
- MeSH terms
- Adult, Aged, Cotinine, Delivery of Health Care, Health Expenditures, Family Practice, Female, Germany, Humans, Male, Middle Aged, Physicians, Family, Primary Health Care, Self Disclosure, Cluster Analysis, Logistic Models, Smoking Cessation
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