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Cost-effectiveness of using continuous positive airway pressure in the treatment of severe obstructive sleep apnoea/hypopnoea syndrome in the UK
Open accessAbstract
OBJECTIVE: A study was undertaken to estimate the cost-effectiveness of using continuous positive airway pressure (CPAP) in the management of patients with severe obstructive sleep apnoea/hypopnoea syndrome (OSAHS) compared with no treatment from the perspective of the UK's National Health Service (NHS). METHODS: A Markov model was constructed to assess the cost-effectiveness of CPAP compared with no treatment. The model depicted the management of a 55-year-old patient with severe OSAHS as defined by an apnoea-hypopnoea index (AHI) >30 and daytime sleepiness (Epworth Sleepiness Scale score >or=12). The model spans a period of 14 years. RESULTS: According to the model, 57% of untreated patients are expected to be alive at the end of 14 years compared with 72% of patients treated with CPAP. Untreated patients are expected to cost the NHS pound10 645 (95% CI pound7988 to pound14,098) per patient over 14 years compared with pound9672 (95% CI pound8057 to pound12,860) per CPAP-treated patient. Treatment with CPAP for a period of 1 year was found not to be a cost-effective option since the cost per quality-adjusted life year (QALY) gained is expected to be > pound20,000, but after 2 years of treatment the cost per QALY gained is expected to be pound10,000 or less and, after 13 years of treatment, CPAP becomes a dominant treatment (ie, more effective than no treatment for less cost). CONCLUSION: Within the limitations of the model, CPAP was found to be clinically more effective than no treatment and, from the perspective of the UK's NHS, a cost-effective strategy after a minimum of 2 years of treatment.
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Guest et al. estimated that cost savings exceeded the costs of treating OSA after 13 years.
“For example, Guest et al. estimated that cost savings exceeded the costs of treating OSA after 13 years.141”
From International Consensus Statement on Obstructive Sleep Apnea (2023) · cites this paper as [141]
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Marin, J. M., Carrizo, S. J., Vicente, E., & Agusti, A. G. (2005) · The Lancet · doi:10.1016/s0140-6736(05)71141-7 · Cited by 4,678
Prevalence of Sleep-disordered Breathing in Women
BIXLER, E. O., VGONTZAS, A. N., LIN, H.-M., TEN HAVE, T., REIN, J., VELA-BUENO, A., & KALES, A. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.3.9911064 · Cited by 1,598
DURÁN, J., ESNAOLA, S., RUBIO, R., & IZTUETA, Á. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.163.3.2005065 · Cited by 1,407
Galiè, N., Rubin, L., Hoeper, M. M., Jansa, P., Al‐Hiti, H., Meyer, G. M. B., Chiossi, E., Kusic‐Pajic, A., & Simonneau, G. (2008) · The Lancet · doi:10.1016/s0140-6736(08)60919-8 · Cited by 917
Long-term Use of CPAP Therapy for Sleep Apnea/Hypopnea Syndrome
McARDLE, N., DEVEREUX, G., HEIDARNEJAD, H., ENGLEMAN, H. M., MACKAY, T. W., & DOUGLAS, N. J. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.159.4.9807111 · Cited by 820
Granger, B. B., Swedberg, K. B., Ekman, I., Granger, C. B., Olofsson, B., McMurray, J. J. V., Yusuf, S., Michelson, E. L., & Pfeffer, M. A. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67760-4 · Cited by 475
Increased incidence of coronary artery disease in sleep apnoea: a long-term follow-up
Peker, Y., Carlson, J. T., & Hedner, J. A. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00107805 · Cited by 456
Reduction in motor vehicle collisions following treatment of sleep apnoea with nasal CPAP
George, C. F. (2001) · Thorax · doi:10.1136/thorax.56.7.508 · Cited by 454
Treatment with Nasal CPAP Decreases Automobile Accidents in Patients with Sleep Apnea
Findley, L. J., Smith, C. E., Hooper, J., DINEEN, M., & Suratt, P. M. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.3.9812154 · Cited by 205
Long-Term Compliance With CPAP Therapy in Obstructive Sleep Apnea Patients and in Snorers
Krieger, J., Kurtz, D., Petiau, C., Sforza, E. A., & Trautmann, D. (1996) · SLEEP · doi:10.1093/sleep/19.suppl_9.s136 · Cited by 201
Drug therapy for obstructive sleep apnoea in adults
Mason, M., Welsh, E. J., & Smith, I. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003002.pub3 · Cited by 192
Campos‐Rodríguez, F., Grilo, A., Pérez‐Ronchel, J., Merino-Sanchez, M., Gonzalez-Benitez, M. A., Beltrán-Robles, M., & Almeida, C. (2006) · CHEST Journal · doi:10.1378/chest.129.6.1459 · Cited by 185
AlBarrak, M., Banno, K., Sabbagh, A. A., Delaive, K., Walld, R., Manfreda, J., & Kryger, M. H. (2005) · SLEEP · doi:10.1093/sleep/28.10.1306 · Cited by 153
Taylor, R. S., Watt, A., Dalal, H. M., Evans, P. H., Campbell, J., Read, K. L. Q., Mourant, A. J., Wingham, J., Thompson, D. R., & Gray, D. P. (2006) · International Journal of Cardiology · doi:10.1016/j.ijcard.2006.07.218 · Cited by 114
Public health and medicolegal implications of sleep apnoea
W.T. McNicholas and J. Krieger on behalf of the Task Force members, & Levy, P. A. (2002) · European Respiratory Journal · doi:10.1183/09031936.02.00404502 · Cited by 111
Mar, J., Rueda, J.-R., Durán-Cantolla, J., Schechter, C. B., & Chilcott, J. B. (2003) · European Respiratory Journal · doi:10.1183/09031936.03.00040903 · Cited by 108
Mazza, S., Pépin, J., Naëgelé, B., Rauch, E., Deschaux, C., Ficheux, P., & Levy, P. A. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00112905 · Cited by 99
Quality Adjusted Life Years Added by Treatment of Obstructive Sleep Apnea
Tousignant, P., Cosio, M. G., Levy, R. D., & Groome, P. A. (1994) · SLEEP · doi:10.1093/sleep/17.1.52 · Cited by 97
Treating sleep apnoea is cost effective
Douglas, N. J. (2002) · Thorax · doi:10.1136/thorax.57.1.93 · Cited by 36
Márquez-Báez, C., Paniagua-Soto, J., & Jm, C.-G. (1998) · PubMed · Cited by 15
Nasal continuous positive airways pressure in the management of sleep apnoea
Chilcott, J. B., Clayton, E., Chada, N., et al. (2000) · White Rose Research Online (University of Leeds, The University of Sheffield, University of York) · Cited by 12
Continuous Positive Airway Pressure Treatment
Iellamo, F., & Montano, N. (2006) · CHEST Journal · doi:10.1378/chest.129.6.1403 · Cited by 10
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International Consensus Statement on Obstructive Sleep Apnea
Chang, J. L., Goldberg, A. N., Alt, J. A., Mohammed, A., Ashbrook, L., Auckley, D., Ayappa, I., Bakhtiar, H., Barrera, J. E., Bartley, B. L., et al. (2023) · International Forum of Allergy & Rhinology · doi:10.1002/alr.23079 · Cited by 350
Jennum, P., & Kjellberg, J. (2011) · Thorax · doi:10.1136/thx.2010.143958 · Cited by 240
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Metadata
- Authors
- Guest, J. F., Helter, M. T., Morga, A., & Stradling, J. R.
- Affiliations
- Catalyst Health Economics Consultants Ltd (GB)
- Churchill Hospital (GB)
- Corresponding author
- Guest, J F
- Venue
- Thorax
- Publisher
- BMJ
- Published
- 2008-10-01
- Volume
- 63
- Issue
- 10
- Pages
- 860-865
- ISSN
- 0040-6376 (ISSN-L)
- OpenAlex
- W2151295847
- Semantic Scholar
- 400e3321761c0363068a047fd82eb7f6c976da91
- Cited by
- 117
- References
- 22
- Citations by year
- 2025: 6 · 2024: 10 · 2023: 6 · 2022: 5 · 2021: 7 · 2020: 6 · 2019: 6 · 2018: 5 · 2017: 6 · 2016: 9 · 2015: 6 · 2014: 8 · 2013: 13 · 2012: 5
- FWCI
- 4.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Thorax (publishedVersion)
- PubMed (publishedVersion)
- HighWire Press Open Archive (submittedVersion)
- Funders
- ResMed
- Topics
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- continuous positive airway pressure, obstructive sleep apnea, cost-effectiveness, Markov model, cost per quality-adjusted life year, National Health Service, apnea-hypopnea index, daytime sleepiness, long-term survival
- MeSH terms
- Accidents, Traffic, Cardiovascular Diseases, Cost-Benefit Analysis, Humans, Patient Compliance, Health Care Costs, Quality-Adjusted Life Years, Sleep Apnea, Obstructive, Continuous Positive Airway Pressure
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