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Cited by 261

The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.

Analysis of lung volume restriction in patients with respiratory muscle weakness.

Open access
De Troyer, A, Borenstein, S, Cordier, R·1980·Thorax

Abstract

We investigated pulmonary mechanics in 25 patients, 9 to 55 years of age, with a variety of generalised neuromuscular diseases and variable degrees of respiratory muscle weakness. The average degree of inspiratory muscle force was 39.2% (range 8-83%) of predicted. The lung volume restriction far exceeded that expected for the degree of muscle weakness: the observed decrement in respiratory muscle force should, theoretically, decrease vital capacity to 78% of its control value, while the mean VC in our patients was only 50% of predicted. Analysis of lung pressure-volume curves indicated that the two principal causes of the disproportionate loss of lung volume were a reduction in lung distensibility probably caused by widespread microatelectasis, and a decrease in the outward pull of the chest wall. Because it reflects both direct (loss of distending pressure) and secondary (alterations in the elastic properties of the lungs and chest wall) effects of respiratory muscle weakness on lung function, we conclude that, in these patients, the vital capacity remains the most useful measurement to follow evolution of the disease process or response to treatment.

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Metadata

Authors
De Troyer, A., Borenstein, S., & Cordier, R.
Venue
Thorax
Publisher
BMJ
Published
1980-08-01
Volume
35
Issue
8
Pages
603-610
ISSN
0040-6376 (ISSN-L)
OpenAlex
W2040606931
Cited by
261
References
7
FWCI
5.51
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Analysis of lung volume restriction in patients with respiratory muscle weakness. https://app.cochat.ai/papers/10.1136/thx.35.8.603
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De Troyer, A., Borenstein, S., & Cordier, R. (1980). Analysis of lung volume restriction in patients with respiratory muscle weakness. Thorax. https://doi.org/10.1136/thx.35.8.603

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