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Mechanisms determining residual volume of the lungs in normal subjects.

Leith, D E, Mead, J·1967·Journal of Applied Physiology

Abstract

residual volume of the lungs in normal subjects. J. Appl. Ph ysiol. 23(2) : 22 I-227. I g67.-Differences between the terminal portions of the flow-volume and volume-time curves of young and old normal subjects during forced expirations indicate that different mechanisms set the lower limit to lung volume in these two age groups. Most young subjects reach the limit quickly (2-4 set); no further volume change occurs in spite of continued effbrt. Most old subjects reach the limit more slowly (I O-I 5 set) and some continue to expire with decreasing flow as long as the effort is maintained. When external pressures assisting expiration were suddenly applied at or near RV, spiro-grams of young individuals showed sudden decrements of lung volume, while those of some old subjects were virtually unin-fluenced. In the former, the static balance of muscle and recoil forces, mainly in the chest Iwall, sets the limit to expiration, and

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Metadata

Authors
Leith, D. E., & Mead, J.
Venue
Journal of Applied Physiology
Published
1967-08
Volume
23
Issue
2
Pages
221-227
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
OpenAlex
W2180474633
Cited by
162
References
0
FWCI
8.00
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Mechanisms determining residual volume of the lungs in normal subjects. https://app.cochat.ai/papers/10.1152/jappl.1967.23.2.221
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Leith, D. E., & Mead, J. (1967). Mechanisms determining residual volume of the lungs in normal subjects. Journal of Applied Physiology. https://doi.org/10.1152/jappl.1967.23.2.221

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.