The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Acute phase proteins in cattle: discrimination between acute and chronic inflammation
Abstract
Acute phase proteins such as serum amyloid A, haptoglobin, and α 1 ‐acid glycoprotein have been identified as markers of inflammation in cattle because they are produced by the liver in response to pro‐inflammatory cytokines. This study was designed to assess whether they could be used to discriminate between acute and chronic inflammation. Their concentrations were measured in serum samples from 81 cattle in which inflammation was classified by thorough clinical examination, supported by postmortem findings, as being acute in severity in 31 and chronic in 50. The classical haematological markers of inflammation were also determined in blood from the animals. Serum amyloid A had a maximum (100 per cent) clinical sensitivity in discriminating between the acute and chronic cases, and haptoglobin had the highest clinical specificity of 76 per cent; counts of neutrophils and band neutrophils had sensitivities of 71 per cent and 42 per cent and specificities of 30 per cent and 72 per cent, respectively. It was concluded that serum amyloid A and haptoglobin may be used to discriminate between acute and chronic inflammatory conditions.
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Citations
Cites
Haptoglobin response to clinical respiratory tract disease in feedlot cattle
Wittum, T. E., Young, C. R., Stanker, L. H., Griffin, D. D., Perino, L. J., & Littledike, E. T. (1996) · American Journal of Veterinary Research · doi:10.2460/ajvr.1996.57.05.646 · Cited by 77
Cited by
Application of acute phase protein measurements in veterinary clinical chemistry
Petersen, H. H., Nielsen, J. P., & Heegaard, P. M. H. (2004) · Veterinary Research · doi:10.1051/vetres:2004002 · Cited by 1,060
Acute phase proteins: Biomarkers of infection and inflammation in veterinary medicine
Eckersall, P. D., & Bell, R. (2010) · The Veterinary Journal · doi:10.1016/j.tvjl.2010.04.009 · Cited by 835
Self-citationSheldon, I. M., Noakes, D. E., Rycroft, A. N., Pfeiffer, D. U., & Dobson, H. (2002) · Reproduction · doi:10.1530/rep.0.1230837 · Cited by 586
Khafipour, E., Krause, D. O., & Plaizier, J. C. (2009) · Journal of Dairy Science · doi:10.3168/jds.2008-1389 · Cited by 554
Influence of Stress and Nutrition on Cattle Immunity
Carroll, J. A., & Forsberg, N. E. (2007) · Veterinary Clinics of North America: Food Animal Practice · doi:10.1016/j.cvfa.2007.01.003 · Cited by 337
Metadata
- Authors
- Horadagoda, N. U., Knox, K. M. G., Gibbs, H. A., Reid, S. W. J., Horadagoda, A., Edwards, S. E. R., & Eckersall, P. D.
- Venue
- Veterinary Record
- Publisher
- Wiley
- Published
- 1999-04
- Volume
- 144
- Issue
- 16
- Pages
- 437-441
- ISSN
- 0042-4900 (ISSN-L)
- 2042-7670
- OpenAlex
- W1980186985
- Cited by
- 376
- References
- 1
- FWCI
- 13.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- Horadagoda, N. U., Knox, K. M. G., Gibbs, H. A., Reid, S. W. J., Horadagoda, A., Edwards, S. E. R., & Eckersall, P. D. (1999). Acute phase proteins in cattle: discrimination between acute and chronic inflammation. Veterinary Record. https://doi.org/10.1136/vr.144.16.437
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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