Effects of taurine supplementation following eccentric exercise in young adults
Abstract
The purpose of the present study was to investigate the effects of taurine supplementation on muscle performance, oxidative stress, and inflammation response after eccentric exercise (EE) in males. Twenty-one participants (mean age, 21 ± 6 years; weight, 78.2 ± 5 kg; height, 176 ± 7 cm) were selected and randomly divided into two groups: placebo (n = 10) and taurine (n = 11). Fourteen days after starting supplementation, subjects performed EE (3 sets until exhaustion, with EE of the elbow flexors on the Scott bench, 80% 1 repetition maximum (RM)). Blood samples were collected and muscle performance was measured on days 1, 14, 16, 18, and 21 after starting the supplements. Then, performance, muscle damage, oxidative stress, and inflammatory markers were analyzed. The taurine supplementation resulted in increased strength levels and thiol total content and decreased muscle soreness, lactate dehydrogenase level, creatine kinase activity, and oxidative damage (xylenol and protein carbonyl). Antioxidant enzymes (superoxide dismutase, catalase, and gluthatione peroxidase) and inflammatory markers (tumor necrosis factor, interleukin-1β (IL-1β), and interleukin-10 (IL-10)) were not altered during the recovery period compared with the placebo group. The results suggest that taurine supplementation represents an important factor in improving performance and decreasing muscle damage and oxidative stress but does not decrease the inflammatory response after EE.
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High bioavailability of nitric oxide increases release of calcium, improving contractile function of skeletal muscle and helping recovery of phosphocreatine reserves, preventing depletion during repeated efforts and improving release and reuptake of calcium in the sarcoplasmic reticulum.
“The high bioavailability of nitric oxide increases release of calcium (Ca 2+ ) improving contractile function of the skeletal muscle [42] and helping recovery of phosphocreatine reserves, which prevents depletion during repeated efforts and improves release and reuptake of calcium in the sarcoplasmic reticulum [43, 44].”
From Dietary and Ergogenic Supplementation to Improve Elite Soccer Players’ Performance (2021) · cites this paper as [43]
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ISSN exercise & sports nutrition review update: research & recommendations
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“Two studies [632, 633] have been completed that examined taurine’s ability to mitigate decrements associated with”
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Dietary and Ergogenic Supplementation to Improve Elite Soccer Players’ Performance
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Retracted
- Authors
- da Silva, L. A., Tromm, C. B., Bom, K. F., Mariano, I., Pozzi, B., da Rosa, G. L., Tuon, T., da Luz, G., Vuolo, F., Petronilho, F., Cassiano, W., De Souza, C. T., & Pinho, R. A.
- Affiliations
- Exercise Biochemistry and Physiology Laboratory, Postgraduate Program in Health Sciences, Health Sciences Unit, Universidade do Extremo Sul Catarinense, 88806-000, Criciúma, SC, Brazil.
- Universidade do Extremo Sul Catarinense (BR)
- Centro Universitário do Espírito Santo (BR)
- Venue
- Applied Physiology, Nutrition, and Metabolism
- Publisher
- Canadian Science Publishing
- Published
- 2014-01
- Volume
- 39
- Issue
- 1
- Pages
- 101-104
- ISSN
- 1715-5312 (ISSN-L)
- 1715-5320
- OpenAlex
- W2105701070
- Cited by
- 82
- References
- 2
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 3 · 2023: 5 · 2022: 11 · 2021: 13 · 2020: 5 · 2019: 7 · 2018: 10 · 2017: 7 · 2016: 4 · 2015: 4 · 2014: 4
- FWCI
- 4.27
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Applied Physiology, Nutrition, and Metabolism (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Aldose Reductase and Taurine
- Keywords
- taurine supplementation, eccentric exercise, exercise-induced muscle damage, oxidative stress, inflammation, muscle performance, muscle soreness, creatine kinase, lactate dehydrogenase, protein carbonyls, antioxidant enzymes, inflammatory cytokines, elbow flexors
- MeSH terms
- Humans, Inflammation, Male, Taurine, Exercise, Oxidative Stress, Muscle, Skeletal, Dietary Supplements, Young Adult
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