The Effects of Caffeine, Taurine, or Caffeine-Taurine Coingestion on Repeat-Sprint Cycling Performance and Physiological Responses
Open accessAbstract
Purpose:To investigate the effects of caffeine (C), taurine (T), caffeine and taurine coingestion (C +T), or placebo (P) on repeated Wingate cycling performance and associated physiological responses.Methods:Seven male team-sport players participated in a randomized, single-blind, crossover study, where they completed 3 Wingate tests, each separated by 2 min, an hour after ingesting: C (5 mg/kg body mass [BM]), T (50 mg/kg BM), C +T (5 mg/kg BM + 50 mg/kg BM), or P (5 mg/kg BM) in a gelatin capsule. Performance was measured on an ergometer, and blood lactate, perceived exertion, heart rate (HR), mean arterial pressure (MAP), and rate pressure product (RPP) were measured at rest (presupplement), baseline (1 h postsupplement), and during and after exercise.Results:Magnitude-based inferences revealed that all of the supplements increased (small to moderate, likely to very likely) mean peak power (MPP), peak power (PP), and mean power (MP) compared to P, with greater MPP, PP, and MP in T compared to C (small, possible). Intrasprint fatigue index (%FI Intra) was greater in T compared to P and C (moderate, likely), and %FI Inter was lower in T compared to C (small, possible). C and C +T increased HR, MAP, and RPP compared to P and T at baseline (moderate to very large, likely to most likely); however, these only remained higher in C compared to all conditions in the final sprint.Conclusions:T elicited greater improvements in performance compared to P, C, or C +T while reducing the typical chronotropic and pressor effects of C.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
A 50 mg/kg dose of taurine outperformed caffeine, placebo and caffeine + taurine on performance changes after repeated Wingate anaerobic capacity tests.
“Warnock et al. [630] reported that a 50 mg/kg dose of taurine outperformed caffeine, placebo and caffeine + taurine on performance changes after repeated Wingate anaerobic capacity tests.”
From ISSN exercise & sports nutrition review update: research & recommendations (2018) · cites this paper as [630]
The Methods and Discussion report a 50 mg/kg taurine condition in repeated Wingate tests and greater power output than placebo. The Discussion describes its advantage over caffeine as only “possibly greater,” while the Results call some taurine–caffeine-plus-taurine differences unclear. The claim overstates the certainty of taurine outperforming every comparator. (LLM, conf=0.82)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Fredholm, B. B., Bättig, K., Holmén, J., Nehlig, A., & Zvartau, E. E. (1999) · Pharmacological Reviews · doi:10.1016/s0031-6997(24)01396-6 · Cited by 2,624 · see citing works
Physiological actions of taurine
Huxtable, R. J. (1992) · Physiological Reviews · doi:10.1152/physrev.1992.72.1.101 · Cited by 2,605 · see citing works
Making Meaningful Inferences About Magnitudes
Batterham, A. M., & Hopkins, W. G. (2006) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.1.1.50 · Cited by 2,186 · see citing works
Caffeine and sports performance
Burke, L. M. (2008) · Applied Physiology Nutrition and Metabolism · doi:10.1139/h08-130 · Cited by 442 · see citing works
Multiple Effects of Caffeine on Simulated High-Intensity Team-Sport Performance
STUART, G. R., Hopkins, W. G., Cook, C. J., & Cairns, S. P. (2005) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000177216.21847.8a · Cited by 220 · see citing works
Taurine Is a Potent Activator of Extrasynaptic GABA A Receptors in the Thalamus
Jia, F., Yue, M. E., Chandra, D., Keramidas, A., Goldstein, P. A., Homanics, G. E., & Harrison, N. L. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.3996-07.2008 · Cited by 171 · see citing works
Mohr, M., Nielsen, J. J., & Bangsbo, J. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01028.2010 · Cited by 162 · see citing works
Do energy drinks contain active components other than caffeine?
McLellan, T. M., & Lieberman, H. R. (2012) · Nutrition Reviews · doi:10.1111/j.1753-4887.2012.00525.x · Cited by 152 · see citing works
Bichler, A., Swenson, A., & Harris, M. A. (2006) · Amino Acids · doi:10.1007/s00726-005-0302-x · Cited by 132 · see citing works
Recent advances in the understanding of skeletal muscle fatigue
Westerblad, H., & Allen, D. G. (2002) · Current Opinion in Rheumatology · doi:10.1097/00002281-200211000-00003 · Cited by 124 · see citing works
Bakker, A. J., & Berg, H. M. (2002) · The Journal of Physiology · doi:10.1113/jphysiol.2001.012872 · Cited by 104 · see citing works
Tallis, J. A., Duncan, M. J., & James, R. S. (2015) · British Journal of Pharmacology · doi:10.1111/bph.13187 · Cited by 104 · see citing works
Rutherford, J. A., Spriet, L. L., & Stellingwerff, T. (2010) · International Journal of Sport Nutrition and Exercise Metabolism · doi:10.1123/ijsnem.20.4.322 · Cited by 101 · see citing works
Caffeine reinforcement: the role of withdrawal
Schuh, K. J., & Griffiths, R. R. (1997) · Psychopharmacology · doi:10.1007/s002130050246 · Cited by 100 · see citing works
Pharmacokinetics of Oral Taurine in Healthy Volunteers
Ghandforoush‐Sattari, M., Mashayekhi, S., Krishna, C., Thompson, J. P., & Routledge, P. A. (2010) · Journal of Amino Acids · doi:10.4061/2010/346237 · Cited by 98 · see citing works
Caffeine and selective visual processing
Kenemans, J. L., & Lorist, M. M. (1995) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(95)00159-t · Cited by 90 · see citing works
Effects of taurine supplementation following eccentric exercise in young adults
da Silva, L. A., Tromm, C. B., Bom, K. F., Mariano, I., Pozzi, B., da Rosa, G. L., Tuon, T., da Luz, G., Vuolo, F., Petronilho, F., et al. (2014) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2012-0229 · Cited by 82 · see citing works
Hamilton, E. J., Berg, H. M., Easton, C. J., et al. (2006) · Amino Acids · doi:10.1007/s00726-006-0291-4 · Cited by 80 · see citing works
The effect of acute taurine ingestion on 3-km running performance in trained middle-distance runners
Balshaw, T. G., Bampouras, T. M., Barry, T. J., & Sparks, S. A. (2013) · Amino Acids · doi:10.1007/s00726-012-1372-1 · Cited by 71 · see citing works
Role of taurine in osmoregulation during endurance exercise
Cuisinier, C., de Welle, J. M., Verbeeck, R. K., POORTMANS, J. R., Ward, R. J., Sturbois, X., & Francaux, M. (2002) · European Journal of Applied Physiology · doi:10.1007/s00421-002-0679-0 · Cited by 59 · see citing works
Decreased taurine concentration in skeletal muscles after exercise for various durations
Matsuzaki, Y., Miyazaki, T., Miyakawa, S., et al. (2002) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-200205000-00011 · Cited by 58 · see citing works
Hajsadeghi, S., Mohammadpour, F., Manteghi, M. J., Kordshakeri, K., Belasi, M. T., Rahmani, E., & Hassanzadeh, M. (2015) · The Anatolian Journal of Cardiology · doi:10.5152/akd.2015.5930 · Cited by 53 · see citing works
Theophylline and caffeine metabolism in man
Arnaud, M., & Welsch, C. (1982) · Vieweg+Teubner eBooks · doi:10.1007/978-3-663-05268-5_18 · Cited by 52 · see citing works
Effects of taurine on Ca2+-dependent force development of skinned muscle fibre preparations
Galler, S., Hutzler, C., & Haller, T. (1990) · Journal of Experimental Biology · doi:10.1242/jeb.152.1.255 · Cited by 51 · see citing works
Milioni, F., Malta, E. D. S., Rocha, L. G. S. D. A., Mesquita, C. A. A., de Freitas, E. C., & Zagatto, A. M. (2016) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2015-0435 · Cited by 44 · see citing works
Doerner, J., Kuetting, D. L. R., Luetkens, J. A., Naehle, C. P., Dabir, D., Homsi, R., Nadal, J., Schild, H. H., & Thomas, D. K. (2014) · International journal of cardiac imaging · doi:10.1007/s10554-014-0577-7 · Cited by 36 · see citing works
Haemodynamic responses following intermittent supramaximal exercise in athletes
Crisafulli, A., Carta, C., Melis, F., Tocco, F., Frongia, F., Santoboni, U. M., Pagliaro, P., & Concu, A. (2004) · Experimental Physiology · doi:10.1113/expphysiol.2004.027946 · Cited by 34 · see citing works
Tallis, J. A., Higgins, M. F., Cox, V. M., Duncan, M. J., & James, R. S. (2013) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2013-0195 · Cited by 30 · see citing works
Lavine (2011) · Cardiology Research · doi:10.4021/cr71w · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
ISSN exercise & sports nutrition review update: research & recommendations
Kerksick, C. M., Wilborn, C. D., Roberts, M. D., Smith-Ryan, A., Kleiner, S. M., Jäger, R., Collins, R., Cooke, M., Davis, J. N., Galvan, E., et al. (2018) · Journal of the International Society of Sports Nutrition · doi:10.1186/s12970-018-0242-y · Cited by 945 · see citing works
Taurine: A Regulator of Cellular Redox Homeostasis and Skeletal Muscle Function
Seidel, U., Huebbe, P., & Rimbach, G. (2019) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201800569 · Cited by 176 · see citing works
- Authors
- Warnock, R., Jeffries, O., Patterson, S., & Waldron, M.
- Affiliations
- St Mary's University Twickenham London (GB)
- University of New England (AU)
- Corresponding author
- Waldron, Mark
- Venue
- International Journal of Sports Physiology and Performance
- Publisher
- Human Kinetics
- Published
- 2017-11-01
- Volume
- 12
- Issue
- 10
- Pages
- 1341-1347
- ISSN
- 1555-0265 (ISSN-L)
- 1555-0273
- OpenAlex
- W2603096308
- Cited by
- 64
- References
- 29
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 9 · 2023: 5 · 2022: 15 · 2021: 4 · 2020: 4 · 2019: 11 · 2018: 6 · 2017: 2
- FWCI
- 6.91
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Sports Physiology and Performance (publishedVersion)
- PubMed (publishedVersion)
- St Mary's University Repository (ULCC) (acceptedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- Topics
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
- Health Sciences › Medicine › Pharmacology › Coffee research and impacts
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
- Keywords
- caffeine, taurine, Wingate test, peak power, chronotropic response, pressor response, rate-pressure product, blood lactate, perceived exertion, team sport athletes, ergogenic aids
- MeSH terms
- Bicycling, Blood Pressure, Caffeine, Exercise Test, Physical Exertion, Heart Rate, Humans, Taurine, Single-Blind Method, Ergometry, Cross-Over Studies, Athletic Performance, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review