Cited by 92Cardiovascular and exercise physiologySports Performance and TrainingGenetics and Physical Performance

Incidence of nonresponse and individual patterns of response following sprint interval training

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Gurd, Brendon J., Giles, Matthew D., Bonafiglia, Jacob T., Raleigh, James P., Boyd, John C., Ma, Jasmin K., Zelt, Jason G.E., Scribbans, Trisha D.·2016·Applied Physiology, Nutrition, and Metabolism

Abstract

The current study sought to explore the incidence of nonresponders for maximal or submaximal performance following a variety of sprint interval training (SIT) protocols. Data from 63 young adults from 5 previously published studies were utilized in the current analysis. Nonresponders were identified using 2 times the typical error (TE) of measurement for peak oxygen uptake (2 × TE = 1.74 mL/(kg·min)), lactate threshold (2 × TE = 15.7 W), or 500 kcal time-to-completion (TTC; 2 × TE = 306 s) trial. TE was determined on separate groups of participants by calculating the test–retest variance for each outcome. The overall rate of nonresponders for peak oxygen uptake across all participants studied was 22% (14/63) with 4 adverse responders observed. No nonresponders for peak oxygen uptake were observed in studies where participants trained 4 times per week (n = 18), while higher rates were observed in most studies requiring training 3 times per week (30%–50%; n = 45). A nonresponse rate of 44% (8/18) and 50% (11/22) was observed for the TTC test and lactate threshold, respectively. No significant correlations were observed between the changes in peak oxygen uptake and TTC (r = 0.014; p = 0.96) or lactate threshold (r = 0.17; p = 0.44). The current analysis demonstrates a significant incidence of nonresponders for peak oxygen uptake and heterogeneity in the individual patterns of response following SIT. Additionally, these data support the importance of training dose and suggest that the incidence of nonresponse may be mitigated by utilizing the optimal dose of SIT.

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Crossref · 10.1139/apnm-2015-0449

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  • Low responders to each exercise stimulus may be as high as 25% in studies of individuals undertaking resistance and endurance training in isolation.

    “The characterisation of individual responses is not a new phenomenon, but the results of studies of individuals undertaking resistance and endurance training in isolation suggest that 'low responders' to each exercise stimulus may be as high as 25% (Timmons et al., 2005;Phillips et al., 2013;Gurd et al., 2016).”

    From Concurrent exercise training: do opposites distract? (2017) · cites this paper as Gurd et al., 2016

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References 25 · Cited by 92

Authors
Gurd, B. J., Giles, M. D., Bonafiglia, J. T., Raleigh, J. P., Boyd, J. C., Ma, J. K., Zelt, J. G. E., & Scribbans, T. D.
Affiliations
Queen's University (CA)
Corresponding author
Gurd, Brendon J.
Venue
Applied Physiology, Nutrition, and Metabolism
Published
2016-03
Volume
41
Issue
3
Pages
229-234
ISSN
  • 1715-5312 (ISSN-L)
  • 1715-5320
OpenAlex
W1898146007
Cited by
92
References
25
Citations by year
2026: 3 · 2025: 2 · 2024: 7 · 2023: 1 · 2022: 6 · 2021: 19 · 2020: 11 · 2019: 13 · 2018: 12 · 2017: 8 · 2016: 9 · 2014: 1
FWCI
18.87
Type
journal article
Language
en
Open access
Locations
  • Applied Physiology Nutrition and Metabolism (publishedVersion)
  • PubMed (publishedVersion)
  • TSpace (University of Toronto) (acceptedVersion)
Topics
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Physical Performance
Keywords
sprint interval training, peak oxygen uptake, lactate threshold, time to exhaustion, training dose, test-retest variability, cardiorespiratory fitness
MeSH terms
High-Intensity Interval Training, Adaptation, Physiological, Adult, Female, Humans, Male, Muscle Contraction, Oxygen Consumption, Running, Time Factors, Biomarkers, Muscle, Skeletal, Lactic Acid, Young Adult

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