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Cited by 195

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Exercise prescription to reverse frailty

Open access
Bray, Nick W., Smart, Rowan R., Jakobi, Jennifer M., Jones, Gareth R.·2016·Applied Physiology, Nutrition, and Metabolism

Abstract

Frailty is a clinical geriatric syndrome caused by physiological deficits across multiple systems. These deficits make it challenging to sustain homeostasis required for the demands of everyday life. Exercise is likely the best therapy to reverse frailty status. Literature to date suggests that pre-frail older adults, those with 1–2 deficits on the Cardiovascular Health Study-Frailty Phenotype (CHS-frailty phenotype), should exercise 2–3 times a week, for 45–60 min. Aerobic, resistance, flexibility, and balance training components should be incorporated but resistance and balance activities should be emphasized. On the other hand, frail (CHS-frailty phenotype ≥ 3 physical deficits) older adults should exercise 3 times per week, for 30–45 min for each session with an emphasis on aerobic training. During aerobic, balance, and flexibility training, both frail and pre-frail older adults should work at an intensity equivalent to a rating of perceived exertion of 3–4 (“somewhat hard”) on the Borg CR10 scale. Resistance-training intensity should be based on a percentage of 1-repetition estimated maximum (1RM). Program onset should occur at 55% of 1RM (endurance) and progress to higher intensities of 80% of 1RM (strength) to maximize functional gains. Exercise is the medicine to reverse or mitigate frailty, preserve quality of life, and restore independent functioning in older adults at risk of frailty.

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Metadata

Authors
Bray, N. W., Smart, R. R., Jakobi, J. M., & Jones, G. R.
Venue
Applied Physiology, Nutrition, and Metabolism
Published
2016-10
Volume
41
Issue
10
Pages
1112-1116
ISSN
  • 1715-5312 (ISSN-L)
  • 1715-5320
OpenAlex
W2521467659
Cited by
195
References
8
FWCI
5.88
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Exercise prescription to reverse frailty. https://app.cochat.ai/papers/10.1139/apnm-2016-0226
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Bray, N. W., Smart, R. R., Jakobi, J. M., & Jones, G. R. (2016). Exercise prescription to reverse frailty. Applied Physiology, Nutrition, and Metabolism. https://doi.org/10.1139/apnm-2016-0226

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