The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Compositional analysis: a valid approach to analyze microbiome high-throughput sequencing data
Open accessAbstract
A workshop held at the 2015 annual meeting of the Canadian Society of Microbiologists highlighted compositional data analysis methods and the importance of exploratory data analysis for the analysis of microbiome data sets generated by high-throughput DNA sequencing. A summary of the content of that workshop, a review of new methods of analysis, and information on the importance of careful analyses are presented herein. The workshop focussed on explaining the rationale behind the use of compositional data analysis, and a demonstration of these methods for the examination of 2 microbiome data sets. A clear understanding of bioinformatics methodologies and the type of data being analyzed is essential, given the growing number of studies uncovering the critical role of the microbiome in health and disease and the need to understand alterations to its composition and function following intervention with fecal transplant, probiotics, diet, and pharmaceutical agents.
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Cites
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Cited by
Microbiome Datasets Are Compositional: And This Is Not Optional
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Analysis of compositions of microbiomes with bias correction
Lin, H., & Peddada, S. D. (2020) · Nature Communications · doi:10.1038/s41467-020-17041-7 · Cited by 2,104
The neuroactive potential of the human gut microbiota in quality of life and depression
Valles-Colomer, M., Falony, G., Darzi, Y., Tigchelaar, E. F., Wang, J., Tito, R. Y., Schiweck, C., Kurilshikov, A., Joossens, M., Wijmenga, C., et al. (2019) · Nature Microbiology · doi:10.1038/s41564-018-0337-x · Cited by 1,963
The person-to-person transmission landscape of the gut and oral microbiomes
Valles-Colomer, M., Blanco-Míguez, A., Manghi, P., Asnicar, F., Dubois, L., Golzato, D., Armanini, F., Cumbo, F., Huang, K. D., Manara, S., et al. (2023) · Nature · doi:10.1038/s41586-022-05620-1 · Cited by 449
Metadata
- Authors
- Gloor, G. B., & Reid, G.
- Venue
- Canadian Journal of Microbiology
- Publisher
- Canadian Science Publishing
- Published
- 2016-08
- Volume
- 62
- Issue
- 8
- Pages
- 692-703
- ISSN
- 0008-4166 (ISSN-L)
- 1480-3275
- OpenAlex
- W2340700016
- Cited by
- 373
- References
- 39
- FWCI
- 12.94
- Type
- journal article
- Language
- en
- Open access
- green
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