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A MODIFIED SPECTROPHOTOMETRIC DETERMINATION OF CHYMOTRYPSIN, TRYPSIN, AND THROMBIN
Abstract
The spectrophotometric procedure proposed by Schwert and Takenaka for the assay of chymotrypsin and trypsin has been modified and extended to include the application to N-benzoyl-L-tyrosine ethyl ester and α-p-toluenesulphonyl-L-arginine methyl ester. The greater degree of sensitivity and specificity thus achieved permits the determination of traces of chymotrypsin in the presence of relatively large amounts of trypsin and vice versa. A similar spectrophotometric procedure for the assay of thrombin is described.
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Citations
Cited by
Shaw, E., Mares-Guia, M., & Cohen, W. (1965) · Biochemistry · doi:10.1021/bi00886a039 · Cited by 517
[4] Trypsinogens and trypsins of various species
Walsh, K. A. (1970) · Methods in Enzymology · doi:10.1016/0076-6879(70)19006-9 · Cited by 455
Protease-specific suppression of pancreatic exocrine secretion
Slaff, J., Jacobson, D., Tillman, C. R., Curington, C., & Toskes, P. (1984) · Gastroenterology · doi:10.1016/0016-5085(84)90124-0 · Cited by 273
MacGregor, I., Parent, J., & Meyer, J. H. (1977) · Gastroenterology · doi:10.1016/s0016-5085(77)80072-3 · Cited by 163
Conjugation of hyaluronan to proteins
Mero, A., Pasqualin, M., Campisi, M., Renier, D., & Pasut, G. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2012.11.090 · Cited by 69
Metadata
- Authors
- Hummel, B. C. W.
- Venue
- Canadian Journal of Biochemistry and Physiology
- Publisher
- Canadian Science Publishing
- Published
- 1959-12-01
- Volume
- 37
- Issue
- 12
- Pages
- 1393-1399
- ISSN
- 0576-5544 (ISSN-L)
- OpenAlex
- W1975176230
- Cited by
- 1,837
- References
- 0
- FWCI
- 3.53
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: A MODIFIED SPECTROPHOTOMETRIC DETERMINATION OF CHYMOTRYPSIN, TRYPSIN, AND THROMBIN. https://app.cochat.ai/papers/10.1139/o59-157
- The paper
- Hummel, B. C. W. (1959). A MODIFIED SPECTROPHOTOMETRIC DETERMINATION OF CHYMOTRYPSIN, TRYPSIN, AND THROMBIN. Canadian Journal of Biochemistry and Physiology. https://doi.org/10.1139/o59-157
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
