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EDGAR: Extraction of Drugs, Genes And Relations from the Biomedical Literature
Open accessAbstract
EDGAR (Extraction of Drugs, Genes and Relations) is a natural language processing system that extracts information about drugs and genes relevant to cancer from the biomedical literature. This automatically extracted information has remarkable potential to facilitate computational analysis in the molecular biology of cancer, and the technology is straightforwardly generalizable to many areas of biomedicine. This paper reports on the mechanisms for automatically generating such assertions and on a simple application, conceptual clustering of documents. The system uses a stochastic part of speech tagger, generates an underspecified syntactic parse and then uses semantic and pragmatic information to construct its assertions. The system builds on two important existing resources: the MEDLINE database of biomedical citations and abstracts and the Unified Medical Language System, which provides syntactic and semantic information about the terms found in biomedical abstracts.
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Cited by
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Jensen, L. J., Saric, J., & Bork, P. (2006) · Nature Reviews Genetics · doi:10.1038/nrg1768 · Cited by 631
Review of Drug Repositioning Approaches and Resources
Xue, H., Li, J., Xie, H., & Wang, Y. (2018) · International Journal of Biological Sciences · doi:10.7150/ijbs.24612 · Cited by 614
Friedman, C., Kra, P., Yu, H., Krauthammer, M., & Rzhetsky, A. (2001) · Bioinformatics · doi:10.1093/bioinformatics/17.suppl_1.s74 · Cited by 507
Comparative experiments on learning information extractors for proteins and their interactions
Bunescu, R., Ge, R., Kate, R. J., Marcotte, E. M., Mooney, R. J., Ramani, A. K., & Wong, Y. W. (2005) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2004.07.016 · Cited by 428
Metadata
- Authors
- Rindflesch, T. C., Tanabe, L., Weinstein, J. N., & Hunter, L.
- Venue
- Biocomputing 2000
- Publisher
- WORLD SCIENTIFIC
- Published
- 1999-12
- Pages
- 517-528
- OpenAlex
- W2023736097
- Cited by
- 418
- References
- 0
- FWCI
- 51.48
- Type
- conference paper
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: EDGAR: Extraction of Drugs, Genes And Relations from the Biomedical Literature. https://app.cochat.ai/papers/10.1142/9789814447331_0049
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- Rindflesch, T. C., Tanabe, L., Weinstein, J. N., & Hunter, L. (1999). EDGAR: Extraction of Drugs, Genes And Relations from the Biomedical Literature. Biocomputing 2000. https://doi.org/10.1142/9789814447331_0049
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
