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VM-UNet: Vision Mamba UNet for Medical Image Segmentation

Open access
Ruan, Jiacheng, Li, Jincheng, Xiang, Suncheng·2025·ACM Transactions on Multimedia Computing, Communications, and Applications

Abstract

In the realm of medical image segmentation, both CNN-based and Transformer-based models have been extensively explored. However, CNNs exhibit limitations in long-range modeling capabilities, whereas Transformers are hampered by their quadratic computational complexity. Recently, State Space Models (SSMs), exemplified by Mamba, have emerged as a promising approach. They not only excel in modeling long-range interactions but also maintain a linear computational complexity. In this paper, leveraging state space models, we propose a U-shape architecture model for medical image segmentation, named Vision Mamba UNet (VM-UNet). Specifically, the Visual State Space (VSS) block is introduced as the foundation block to capture extensive contextual information, and an asymmetrical encoder-decoder structure is constructed with fewer convolution layers to save calculation cost. We conduct comprehensive experiments on the ISIC17, ISIC18, and Synapse datasets, and the results indicate that VM-UNet performs competitively in medical image segmentation tasks, e.g. obtaining 89.03, 89.71 and 81.08 in terms of DSC score on three datasets respectively. To our best knowledge, this is the first medical image segmentation model constructed based on the pure SSM-based model. We aim to establish a baseline and provide valuable insights for the future development of more efficient and effective SSM-based segmentation systems. Our code is available at https://github.com/JCruan519/VM-UNet .

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Metadata

Authors
Ruan, J., Li, J., & Xiang, S.
Venue
ACM Transactions on Multimedia Computing, Communications, and Applications
Published
2025-09-16
ISSN
  • 1551-6857 (ISSN-L)
  • 1551-6865
OpenAlex
W4414243662
Cited by
804
References
20
FWCI
274.80
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: VM-UNet: Vision Mamba UNet for Medical Image Segmentation. https://app.cochat.ai/papers/10.1145/3767748
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Ruan, J., Li, J., & Xiang, S. (2025). VM-UNet: Vision Mamba UNet for Medical Image Segmentation. ACM Transactions on Multimedia Computing, Communications, and Applications. https://doi.org/10.1145/3767748

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