The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Functional Architecture of the Nuclear Pore Complex
Abstract
The nuclear pore complex (NPC) is the sole gateway between the nucleus and the cytoplasm. NPCs fuse the inner and outer nuclear membranes to form aqueous translocation channels that allow the free diffusion of small molecules and ions, as well as receptor-mediated transport of large macromolecules. The NPC regulates nucleocytoplasmic transport of macromolecules, utilizing soluble receptors that identify and present cargo to the NPC, in a highly selective manner to maintain cellular functions. The NPC is composed of multiple copies of approximately 30 different proteins, termed nucleoporins, which assemble to form one of the largest multiprotein assemblies in the cell. In this review, we address structural and functional aspects of this fundamental cellular machinery.
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Cites
The transmembrane nucleoporin NDC1 is required for targeting of ALADIN to nuclear pore complexes
Yamazumi, Y., Kamiya, A., Nishida, A., Nishihara, A., Iemura, S.-I., Natsume, T., & Akiyama, T. (2009) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2009.08.096 · Cited by 34
Cited by
Probing nuclear pore complex architecture with proximity-dependent biotinylation
Kim, D. I., KC, B., Zhu, W., Motamedchaboki, K., Doye, V., & Roux, K. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1406459111 · Cited by 560
The Nuclear Pore Complex as a Flexible and Dynamic Gate
Knockenhauer, K. E., & Schwartz, T. U. (2016) · Cell · doi:10.1016/j.cell.2016.01.034 · Cited by 406
SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells
Han, K. Y., Kim, K.-T., Joung, J.-G., Son, D.-S., Kim, Y. J., Jo, A., Jeon, H.-J., Moon, H.-S., Yoo, C. E., Chung, W., et al. (2018) · Genome Research · doi:10.1101/gr.223263.117 · Cited by 143
Chen, K., Guo, L., Zhang, J., Chen, Q., Wang, K., Li, C., Li, W., Qiao, M., Zhao, X., Hu, H., et al. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.11.004 · Cited by 37
Cellular maintenance of nuclear protein homeostasis.
Gallagher, P. S., Oeser, M. L., Abraham, A.-C., Kaganovich, D., & Gardner, R. G. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1530-y · Cited by 22
Metadata
- Authors
- Grossman, E., Medalia, O., & Zwerger, M.
- Venue
- Annual Review of Biophysics
- Publisher
- Annual Reviews
- Published
- 2012-06-09
- Volume
- 41
- Issue
- 1
- Pages
- 557-584
- ISSN
- 1936-122X (ISSN-L)
- 1936-1238
- OpenAlex
- W2103851941
- Cited by
- 274
- References
- 1
- FWCI
- 1.63
- Type
- journal article
- Language
- en
- Open access
- closed
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- Grossman, E., Medalia, O., & Zwerger, M. (2012). Functional Architecture of the Nuclear Pore Complex. Annual Review of Biophysics. https://doi.org/10.1146/annurev-biophys-050511-102328
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