Heterochromatin: Guardian of the Genome

Hallmarks of Cancer: The Next Generation

Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590

Initial sequencing and analysis of the human genome

International Human Genome Sequencing Consortium, Whitehead Institute for Biomedical Research, C. F. G. R., Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., Devon, K., Dewar, K., et al. (2001) · Nature · doi:10.1038/35057062 · Cited by 24,216

The DNA Damage Response: Making It Safe to Play with Knives

Ciccia, A., & Elledge, S. J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.019 · Cited by 4,368

Transposable elements and the epigenetic regulation of the genome

Slotkin, R. K., & Martienssen, R. (2007) · Nature Reviews Genetics · doi:10.1038/nrg2072 · Cited by 2,044

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

Guelen, L., Pagie, L., Brasset, É., Meuleman, W. R. A., Faza, M. B., Talhout, W., Eussen, B. H. J., de Klein, A., Wessels, L. F. A., de Laat, W. L., et al. (2008) · Nature · doi:10.1038/nature06947 · Cited by 2,042

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Gorgoulis, V. G., Vassiliou, L.-V. F., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., Venere, M., DiTullio, R. A., Kastrinakis, N. G., Levy, B., et al. (2005) · Nature · doi:10.1038/nature03485 · Cited by 2,009

Phase separation drives heterochromatin domain formation

Strom, A. R., Emelyanov, A. V., Mir, M., Fyodorov, D. V., Darzacq, X., & Karpen, G. H. (2017) · Nature · doi:10.1038/nature22989 · Cited by 1,789

Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability

Peters, A. H. F. M., O'Carroll, D., Scherthan, H., Mechtler, K., Sauer, S., Schöfer, C., Weipoltshammer, K., Pagani, M., Lachner, M., Kohlmaier, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00542-6 · Cited by 1,766

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

Larson, A. G., Elnatan, D., Keenen, M. M., Trnka, M. J., Johnston, J. B., Burlingame, A. L., Agard, D. A., Redding, S., & Narlikar, G. J. (2017) · Nature · doi:10.1038/nature22822 · Cited by 1,717

The impact of retrotransposons on human genome evolution

Cordaux, R., & Batzer, M. A. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2640 · Cited by 1,692

The bromodomain inhibitor JQ1 is a molecular glue targeting centromeresPreprint

Corless, S., Pratap-Singh, N., Benabdallah, N. S., Böhm, J., Simon, A. M., Dolejš, V., Anders, S., Banito, A., & Erhardt, S. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.15.532673 · Cited by 5

Affinity hierarchies and amphiphilic proteins underlie the co-assembly of nucleolar and heterochromatin condensatesPreprint

Rajshekar, S., Adame-Arana, O., Bajpai, G., Colmenares, S. U., Lin, K., Safran, S. A., & Karpen, G. H. (2023) · Research Square · doi:10.1101/2023.07.06.547894 · Cited by 5

Endogenous Retroviral Sequences Behave as Putative Enhancers Controlling Gene Expression through HP1-Regulated Long-Range Chromatin Interactions

Calvet, S., Sallis, S., Saksouk, N., Rebouissou, C., Teyssier, C., Lesne, A., Cammas, F. M., & Forné, T. (2022) · Cells · doi:10.3390/cells11152392 · Cited by 4

Epigenetic Modifications in the Retinal Pigment Epithelium of the Eye During RPE-Related Regeneration or Retinal Diseases in Vertebrates

Grigoryan, E. N., & Markitantova, Y. V. (2025) · Biomedicines · doi:10.3390/biomedicines13071552 · Cited by 4

PhpCNF-Y transcription factor infiltrates heterochromatin to generate cryptic intron-containing transcripts crucial for small RNA production

Srivastav, M. K., Folco, H. D., Nathanailidou, P., Anil, A. T., Vijayakumari, D., Jain, S., Dhakshnamoorthy, J., O’Neill, M. J., Andrésson, Þ., Wheeler, D. L., et al. (2025) · Nature Communications · doi:10.1038/s41467-024-55736-3 · Cited by 4

Coinhibition of Aurora Kinase B and SUV4-20H Induces Synthetic Lethality in Wild-type p53-Deficient Cancer Cells

Duan, L., O’Hara, K. M., Caldemeyer, A., & Maki, C. G. (2025) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-24-0928 · Cited by 4

From minor loci to major players? Satellite DNA diversification in Crepis sensu stricto

Senderowicz, M., Borowska-Żuchowska, N., Yücel, G., Nowak, T., Daini, G., & Kolano, B. A. (2025) · Chromosome Research · doi:10.1007/s10577-025-09783-1 · Cited by 4

Cause and effect in epigenetics – where lies the truth, and how can experiments reveal it?

Klutstein, M. (2020) · BioEssays · doi:10.1002/bies.202000262 · Cited by 4

A dual, catalytic role for the fission yeast Ccr4-Not complex in gene silencing and heterochromatin spreading

Challal, D., Menant, A., Goksal, C., Leroy, E., Al‐Sady, B., & Rougemaille, M. (2023) · Genetics · doi:10.1093/genetics/iyad108 · Cited by 4

Epigenetic Modeling of Jumping Translocations of 1q Heterochromatin in Acute Myeloid Leukemia After 5'‐Azacytidine Treatment

Fernandez, A. G. L., Nardelli, C., Pierini, V., Crescenzi, B., Pellanera, F., Matteucci, C., Crocioni, M., Arniani, S., Battista, V. D., Quintini, M., et al. (2024) · Genes Chromosomes and Cancer · doi:10.1002/gcc.70013 · Cited by 4

Rex1BD and the 14-3-3 protein control heterochromatin organization at tandem repeats by linking RNAi and HDAC

Gao, J., Sun, W., Li, J., Ban, H., Zhang, T., Liao, J., Kim, N., Lee, S. H., Dong, Q., Madramootoo, R., et al. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2309359120 · Cited by 3

Genome wide hypomethylation and youth-associated DNA gap reduction promoting DNA damage and senescence-associated pathogenesis

Watcharanurak, P., & Mutirangura, A. (2023) · Medical Research Archives · doi:10.18103/mra.v11i12.4952 · Cited by 4

Chromatin organization and behavior in HRAS-transformed mouse fibroblasts

Otsuka, A., Minami, K., Higashi, K., Kawaguchi, A., Tamura, S., Ide, S., Hendzel, M. J., Kurokawa, K., & Maeshima, K. (2024) · Chromosoma · doi:10.1007/s00412-024-00817-x · Cited by 4

Mass Spectrometry to Study Chromatin Compaction

Stransky, S., Aguilan, J. T., Lachowicz, J. C., Madrid-Aliste, C. J., Nieves, E., & Sidoli, S. (2020) · Biology · doi:10.3390/biology9060140 · Cited by 4

REC8-cohesin, chromatin and transcription orchestrate meiotic recombination in the Arabidopsis genomePreprint

Lambing, C., Tock, A. J., Choi, K., Topp, S. D., Kuo, P. C., Blackwell, A. R., Zhao, X., Osman, K., Higgins, J. D., Franklin, F. C. H., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/512400 · Cited by 4

The H3.3 K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylationPreprint

Sinha, J., Nickels, J. F., Thurm, A. R., Ludwig, C., Archibald, B. N., Hinks, M. M., Wan, J., Dong, F., & Bintu, L. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.10.13.562147 · Cited by 4

The role of chromatin in retroviral preintegration complex function

Sapp, N., Prakash, P., Chakraborty, R., Balasubramaniam, M., & Dash, C. (2025) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2025.110440 · Cited by 3

The Noncoding Mutational Landscape of Pancreatic Cancer Reveals Recurrent Somatic Mutations in Enhancer Regions

Hayashi, A., Ho, Y.-J., Makohon-Moore, A. P., Zucker, A., Hong, J., Umeda, S., Karnoub, E.-R. R., Huang, J., Baez, P., Kappagantula, R. L., et al. (2025) · Cancer Research Communications · doi:10.1158/2767-9764.crc-24-0167 · Cited by 4

Repeat-associated heterochromatin expansion in Acyclania tenebrosa, a noctuid with one of the largest lepidopteran genomes

Gasparotto, A. E., Ferretti, A. B. S. M., Alves-Gomes, R. T., Soares, F. A. F., Orsetti, A., Clarindo, W. R., & Cabral-de-Mello, D. C. (2026) · BMC Genomics · doi:10.1186/s12864-026-12600-6 · Cited by 3

Transposable elements as drivers of genome evolution in Drosophila virilis

Rezvykh, A. P., Kulikova, D. A., Zelentsova, E. S., Protsenko, L., Bespalova, A. V., Guseva, I. O., Blumenstiel, J. P., Евгеньев, М. Б., & Funikov, S. Y. (2026) · Nucleic Acids Research · doi:10.1093/nar/gkag139 · Cited by 4

Transcriptional competence defines the heterochromatin nucleating potential of isolated MSR units

Lo, Y.-H., Shukeir, N., Erikson, G. A., Edupuganti, R. R., Ching, R. W., Puri, D., Jerabek, L., Shiekhattar, R., & Jenuwein, T. (2026) · Nature Communications · doi:10.1038/s41467-026-70991-2 · Cited by 3

Position Effect Variegation: Role of the Local Chromatin Context in Gene Expression Regulation

Boldyreva, L. V., Andreyeva, E. N., & Pindyurin, A. V. (2022) · Molecular Biology · doi:10.1134/s0026893322030049 · Cited by 6

LOXL 2‐mediated chromatin compaction is required to maintain the oncogenic properties of triple‐negative breast cancer cells

Serra‐Bardenys, G., Blanco, E., Escudero‐Iriarte, C., Serra-Camprubí, Q., Querol, J., Pascual‐Reguant, L., Morancho, B., Escorihuela, M., Tissera, N. S., Sabé, A., et al. (2024) · FEBS Journal · doi:10.1111/febs.17112 · Cited by 3

PHF2-mediated H3K9me balance orchestrates heterochromatin stability and neural progenitor proliferation

Aguirre, S., Pappa, S., Serna‐Pujol, N., Padilla, N., Iacobucci, S., Nacht, A. S., Vicent, G. P., Jordan, A., de la Cruz, X., & Martínez‐Balbás, M. A. (2024) · EMBO Reports · doi:10.1038/s44319-024-00178-7 · Cited by 3

Prevalent Fast Evolution of Genes Involved in Heterochromatin Functions

Lin, L., Huang, Y., McIntyre, J., Chang, C.-H., Colmenares, S. U., & Lee, Y. C. G. (2024) · Molecular Biology and Evolution · doi:10.1093/molbev/msae181 · Cited by 3

1 Chromatin Structure and Function in Neurospora crassa

Courtney, A. J., Ferraro, A. R., Klocko, A. D., & Lewis, Z. (2020) · Springer eBooks · doi:10.1007/978-3-030-49924-2_1 · Cited by 3

The Cell Biology of Heterochromatin

Warecki, B., & Sullivan, W. (2022) · Cells · doi:10.3390/cells11071247 · Cited by 3

H3K9me2 genome-wide distribution in the holocentric insect Spodoptera frugiperda (Lepidoptera: Noctuidae)

Nhim, S., Gimenez, S., Naït-Saïdi, R., Séverac, D., Nam, K., d’Alençon, E., & Nègre, N. (2021) · Genomics · doi:10.1016/j.ygeno.2021.12.014 · Cited by 3

Safeguarding Drosophila female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

Shapiro-Kulnane, L., Selengut, M., & Salz, H. K. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010568 · Cited by 3

ATAC-See: A Tn5 Transposase-Mediated Assay for Detection of Chromatin Accessibility with Imaging

Dang, Y., Yadav, R. P., & Chen, X. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-2899-7_15 · Cited by 4

Chromosome damage in regions with different levels of air pollution

Musilová, P., Kadlcikova, D., Hradská, H., Vozdová, M., Selingerová, I., Černohorská, H., Šalát, D., & Rubes, J. (2023) · Environmental and Molecular Mutagenesis · doi:10.1002/em.22562 · Cited by 3

The effects of chromosome polymorphism on the clinical outcomes of in vitro fertilization/embryo transfer-assisted reproduction

Zhang, X., Zhang, Y., Liang, L., Zhang, Z., Wu, Y., Zhang, X.-L., & Wu, X. (2023) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2023.2238863 · Cited by 3

HHCDB: a database of human heterochromatin regions

Wang, H., Su, M., Xing, J., Zhou, J., Wang, J., Chen, L., Dong, H., Xue, W., Liu, Y., Wu, Q., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad954 · Cited by 3

The Cross-Regulation Between Set1, Clr4, and Lsd1/2 in Schizosaccharomyces pombe

Liu, H., Marayati, B. F., de la Cerda, D. A., Lemezis, B. M., Gao, J., Song, Q., Chen, M., & Reid, K. Z. (2024) · PLoS Genetics · doi:10.1371/journal.pgen.1011107 · Cited by 3

The Proteomic Composition and Organization of Constitutive Heterochromatin in Mouse Tissues

Schmidt, A., Zhang, H., Schmitt, S., Rausch, C., Popp, O., Chen, J., Cmarko, D., Butter, F., Dittmar, G. A. G., Lermyte, F., et al. (2024) · Cells · doi:10.3390/cells13020139 · Cited by 3

DNA Damage, Genome Stability, and Adaptation: A Question of Chance or Necessity?

Herrick, J. (2024) · Genes · doi:10.3390/genes15040520 · Cited by 3

The silent guardian: unraveling the roles of H3K9me3 in genome maintenance

Li, Z., & Zhang, Z. (2024) · Genome Instability & Disease · doi:10.1007/s42764-024-00131-x · Cited by 3

RID is required for both repeat-induced point mutation and nucleation of a novel transitional heterochromatic state for euchromatic repeats

He, Z., Wu, N., Yao, R., Tan, H., Sun, Y., Chen, J., Xue, L., Chen, X., Yang, S., Hurst, L. D., et al. (2025) · Nucleic Acids Research · doi:10.1093/nar/gkaf263 · Cited by 3

Heterochromatin-based silencing of a foreign tandem repeat in Drosophila melanogaster shows unusual biochemistry and temperature sensitivity

Gu, T., Gracheva, E., Lee, M., Leung, W., Bieser, S., Nielsen, A., Smiley, A. T., Vuong, N. N. T., Walther, M., Reuter, G., et al. (2025) · Genetics · doi:10.1093/genetics/iyaf275 · Cited by 3

Genome Evolution in Amphibians

Herrick, J., & Sclavi, B. (2020) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0028996 · Cited by 3

Evolutionary Dynamics of Non-Coding Regions in Pancreatic Ductal AdenocarcinomaPreprint

Hayashi, A., Ho, Y.-J., Makohon-Moore, A. P., Zucker, A., Hong, J., Reiter, J. G., Huang, J., Zhang, L., Attiyeh, M. A., Baez, P., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.09.11.294389 · Cited by 3

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX complexPreprint

Schnabl, J., Wang, J., Hohmann, U., Gehre, M., Batki, J., Andreev, V. I., Purkhauser, K., Fasching, N., Duchek, P., Novatchkova, M., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.01.08.425619 · Cited by 3

HPL-2/HP1 and MET-2/SETDB1 bind distinct co-factors that promote heterochromatic foci, gene repression and organogenesis independently of H3K9 methylationPreprint

Delaney, C. E., Fol, L., You, J. E., Gruenewald, S. B., Ferrario, E., Gasser, S. M., Moeckel, M. M., Stelzl, L., Padeken, J., & Mango, S. E. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.29.615660 · Cited by 3

Epigenetic Control of TERRA by FTSJ3 is Critical for Telomerase-Driven CancersPreprint

Price, J. D. W., Vizeacoumar, F. S., Abuhussein, O., Maranda, V., Zhang, Y., Adachi, H., Kyrylenko, L., Pozzo, A. R., Dong, H., Gong, L. H., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.01.26.634101 · Cited by 3

Targeted editing of pericentromeric satellite DNA alters sensitivity to meiotic drivePreprint

Eickbush, D. G., Rahmat, J., Lindsay, M., Bowers, J., Fuda, N. J., & Larracuente, A. M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.18.700156 · Cited by 3

Protection of the genome and the central exome by peripheral non‐coding DNA against DNA damage in health, ageing and age‐related diseases

Qiu, G., Fu, M., Zheng, X., & Huang, C. (2024) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.13151 · Cited by 3

The nuclear poly(A)-binding protein Pab2/PABPN1 promotes heterochromatin assembly through the formation of Pab2 nuclear condensates

Liu, Z., Song, X., Thillainadesan, G., & Sugiyama, T. (2025) · PLoS Genetics · doi:10.1371/journal.pgen.1011647 · Cited by 2

The isoflavone genistein selectively stimulates major satellite repeat transcription in mouse heterochromatin

Fuhrmann, T., Shukeir, N., Ching, R. W., Erikson, G. A., Dou, Y., Sawitzki, Z., Onishi‐Seebacher, M., Galan, C., & Jenuwein, T. (2025) · Epigenetics & Chromatin · doi:10.1186/s13072-025-00623-4 · Cited by 2

High interferon response signatures in SLE patient leukocytes are associated with increased transposable element expression in gene introns and intergenic regions

Arteaga-Vazquez, L. J., Sepúlveda, H., Reveles, B. V., Suzuki, K., KALUNIAN, K. C., Ay, F., Boothby, M. R., & Rao, A. (2025) · Mobile DNA · doi:10.1186/s13100-025-00377-6 · Cited by 5

An H3K14ub-H3K9me3 feedback circuit governs heterochromatin spreading and inheritance in fission yeast

Toda, T., Zang, J., Qi, H., Fang, Y., Jiang, P., Shan, C., Wong, J., & Jia, S. (2026) · Nature Communications · doi:10.1038/s41467-026-70276-8 · Cited by 2

Arginine methylation-dependent stabilization of SUV39H1 promotes breast cancer growth

Zhao, W., Wang, G., Wang, P., Ma, B., Liu, B., Fu, Y., Tang, Y., Duan, X., Zhou, K., Zhang, J., et al. (2026) · Oncogene · doi:10.1038/s41388-026-03712-0 · Cited by 2

Nuclear Mechanics and Nuclear Mechanotransduction in Cancer Cell Migration and Invasion

Mierke, C. T. (2026) · Biomolecules · doi:10.3390/biom16030457 · Cited by 2

H3K9 trimethylation homeostasis: mechanisms, crosstalk, and cancer relevance

Zhou, L., Wu, Y., & Kang, T. (2026) · Trends in Cell Biology · doi:10.1016/j.tcb.2026.02.002 · Cited by 2

Satellite DNA sequence dictates pericentromere heterochromatin formation and function

Lamelza, P., Parrado, M., Leara, K., Balboula, A. Z., Keane, T., & Lampson, M. A. (2026) · Science Advances · doi:10.1126/sciadv.ady2267 · Cited by 2

The emerging H3K9me3 chromatin landscape during zebrafish embryogenesis

Duval, K. L., Artis, A. R., & Goll, M. G. (2024) · Genetics · doi:10.1093/genetics/iyae138 · Cited by 2

A complex interplay between histone variants and DNA methylation

Edera, A., & Quadrana, L. (2025) · Journal of Experimental Botany · doi:10.1093/jxb/eraf030 · Cited by 2

Exploring the molecular differentiation of sex chromosomes in Anastrepha fraterculus sp. 1 using comparative genomic hybridization (CGH)

Giardini, M. C., Milla, F. H., Conte, C. A., Lanzavecchia, S. B., & Nieves, M. (2025) · Molecular Biology Reports · doi:10.1007/s11033-025-10277-w · Cited by 2

Functional involvement of RNAs and intrinsically disordered proteins in the assembly of heterochromatin

Obuse, C., & Nakayama, J. (2025) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2025.130790 · Cited by 2

Increased genome size is caused by heterochromatin addition in two non-related bat species, Hesperoptenus doriae and Philetor brachypterus (Vespertilionidae, Chiroptera, Mammalia)

Volleth, M., Greilhuber, J., Heller, K., Müller, S., Yong, H.-S., & Loidl, J. (2023) · Chromosoma · doi:10.1007/s00412-023-00802-w · Cited by 2

m6A regulates heterochromatin in mammalian embryonic stem cells

Xu, W., & Shen, H. (2024) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2024.102196 · Cited by 2

Heterochromatin repeat organization at an individual level: Rex1BD and the 14‐3‐3 protein coordinate to shape the epigenetic landscape within heterochromatin repeats

Gao, J., & Li, F. (2024) · BioEssays · doi:10.1002/bies.202400030 · Cited by 3

A role for Gcn5 in heterochromatin structure, gene silencing and NER at the HML locus in budding yeastPreprint

Chen, H., Zhang, L., Wang, Q., He, C., Dender, L., & Gong, F. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.28.433071 · Cited by 2

Alternative end-joining results in smaller deletions in heterochromatin relative to euchromatinPreprint

Miller, J. M., Prange, S. E., Ji, H., Rau, A. R., Khodaverdian, V. Y., Li, X., Patel, A., Butova, N. L., Lutter, A., Chung, H. S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.03.03.531058 · Cited by 2

A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemiaPreprint

Dong, Z., Sepúlveda, H., Arteaga-Vazquez, L. J., Blouin, C., Fernandez, J. A., Binder, M., Chou, W., Tien, H., Patnaik, M. M., Faulkner, G. J., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.30.578015 · Cited by 2

Species-specific satellite DNA composition dictates PRC1-mediated pericentric heterochromatinPreprint

Lamelza, P., Parrado, M., & Lampson, M. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.11.617947 · Cited by 2

Distinct interferon response patterns link to increased transposable element expression in leukocytes of systemic lupus erythematosus patientsPreprint

Arteaga-Vazquez, L. J., Sepúlveda, H., Reveles, B. V., Suzuki, K., KALUNIAN, K. C., Ay, F., Boothby, M. R., & Rao, A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.05.30.657099 · Cited by 2

Chromosome-specific induction of micronuclei and chromosomal aberrations by mitomycin C: Involvement of human chromosomes 9, 1 and 16

Catalán, J., Järventaus, H., Falck, G. C. ‐., Moreno, C., & Norppa, H. (2024) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/j.mrgentox.2024.503753 · Cited by 1

Polymer physics view of peripheral chromatin: de Gennes' self-similar carpet

Sarıyer, O. S., & Erbaş, A. (2024) · Physical review. E · doi:10.1103/physreve.109.054403 · Cited by 1

The Ty1 retrotransposon harbors a DNA region that performs dual functions as both a gene silencing and chromatin insulator

Masumoto, H., Muto, H., Yano, K., Kurosaki, Y., & Niki, H. (2024) · Scientific Reports · doi:10.1038/s41598-024-67242-z · Cited by 1

Liquid Guardians: Biomolecular Condensates Shield Heterochromatin Against Cellular Senescence

Xie, J., & Han, Z. (2025) · BioEssays · doi:10.1002/bies.70026 · Cited by 1

HP1 isoforms direct repair pathway choice in response to heterochromatin double-strand breaks

Bohra, D., & Mazumder, A. (2025) · The Journal of Cell Biology · doi:10.1083/jcb.202407146 · Cited by 3

BMI1 represses G-quadruplex DNA formation to maintain genomic stability during replication

Hanna, R., Deneault, É., & Bernier, G. (2026) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2026.111172 · Cited by 1

NuMA promotes constitutive heterochromatin compaction by stabilizing linker histone H1 on chromatin

Wang, Y., Zhao, W., Niu, J., Liu, C., Wang, X., Yuan, W., Ai, S., Baumeister, W. P., Li, G., He, A., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2025.116901 · Cited by 2

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

Wang, Q., Sun, X., Han, X., Zhang, X., Wang, W., Wang, H., Ren, H., & Gu, L. (2026) · MedComm – Oncology · doi:10.1002/mog2.70054 · Cited by 1

Chromatin organization as a mediator of multigenerational metabolic disruption

Díaz-Castillo, C., Walker, E. W., & Chamorro-García, R. (2026) · Current Opinion in Endocrine and Metabolic Research · doi:10.1016/j.coemr.2026.100605 · Cited by 1

Associations between mechanical stress and epigenetic modifications in outer retinal layer remodeling in high myopia

Xu, J., Wang, L., & Shen, Z. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1780606 · Cited by 1

Molecular basis of chromosome segregation and age-associated errors in oocyte meiosis I

Kitajima, T. S. (2026) · Biology of Reproduction · doi:10.1093/biolre/ioag086 · Cited by 1

Hp1bp3 loss links chromatin reorganization to metabolic vulnerability in glioma

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A Screening Method for Identification of Heterochromatin-Promoting Drugs Using Drosophila

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Analysis of the in vitro response of the Sapajus cay (Primates: Platyrrhini) genome to exposure to the radiomimetic bleomycin

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Two subpopulations of progenitors of leukemic lineages in human myeloid leukemias exhibit different heterochromatin condensation state in central and peripheral nuclear regions (A morphological note with additional original observations)

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Maintaining oxidized H3 in heterochromatin is required for the oncogenic capacity of triple-negative breast cancer cellsPreprint

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Clr4 SUV39H1 ubiquitination and non-coding RNA mediate transcriptional silencing via heterochromatic phase transitionsPreprint

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HIV-1 preintegration complex preferentially integrates the viral DNA into nucleosomes containing trimethylated histone 3-lysine 36 modificationPreprint

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Alternative end-joining results in smaller deletions in heterochromatin relative to euchromatinPreprint

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Auto-methylation of the histone methyltransferase SetDB1 at its histone-mimic motifs ensures the spreading and maintenance of heterochromatinPreprint

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New Histone H4 variant and H2B variant Exhibits Distinct Genomic Locations, Chromatin Affinities, and Dynamics Throughout Life Cycle and Cell Cycle of Trypanosoma cruziPreprint

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An image-based CRISPR screen reveals splicing-mediated control of HP1α condensatesPreprint

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