The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Structure and Regulation of the Type VI Secretion System
Open accessAbstract
The type VI secretion system (T6SS) is a complex and widespread gram-negative bacterial export pathway with the capacity to translocate protein effectors into a diversity of target cell types. Current structural models of the T6SS indicate that the apparatus is composed of at least two complexes, a dynamic bacteriophage-like structure and a cell-envelope-spanning membrane-associated assembly. How these complexes interact to promote effector secretion and cell targeting remains a major question in the field. As a contact-dependent pathway with specific cellular targets, the T6SS is subject to tight regulation. Thus, the identification of regulatory elements that control T6S expression continues to shape our understanding of the environmental circumstances relevant to its function. This review discusses recent progress toward characterizing T6S structure and regulation.
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Cites
Bacterial Biofilms: A Common Cause of Persistent Infections
Costerton, J. W., Stewart, P. S., & Greenberg, E. P. (1999) · Science · doi:10.1126/science.284.5418.1318 · Cited by 12,167
Pseudomonas aeruginosa Displays Multiple Phenotypes during Development as a Biofilm
Sauer, K., Camper, A. K., Ehrlich, G. D., Costerton, J. W., & Davies, D. G. (2002) · Journal of Bacteriology · doi:10.1128/jb.184.4.1140-1154.2002 · Cited by 1,691
This Is Not Your Mother's Repressor: the Complex Role of Fur in Pathogenesis
Carpenter, B. M., Whitmire, J. M., & Merrell, D. S. (2009) · Infection and Immunity · doi:10.1128/iai.00116-09 · Cited by 215
Cited by
Rhs proteins from diverse bacteria mediate intercellular competition
Koskiniemi, S., Lamoureux, J. G., Nikolakakis, K. C., t'Kint de Roodenbeke, C., Kaplan, M. D., Low, D. A., & Hayes, C. S. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1300627110 · Cited by 414
Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors
Russell, A. B., LeRoux, M., Hathazi, K., Agnello, D. M., Ishikawa, T., Wiggins, P. A., Wai, S. N., & Mougous, J. D. (2013) · Nature · doi:10.1038/nature12074 · Cited by 414
Self-citationNeutrophil elastase-mediated increase in airway temperature during inflammation
Schmidt, A., Belaaouaj, A., Bissinger, R., Koller, G., Malleret, L., D'Orazio, C., Facchinelli, M., Schulte-Hubbert, B., Molinaro, A., Holst, O., et al. (2014) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2014.03.004 · Cited by 30
Miller, D. P., Wang, Q., Weinberg, A., & Lamont, R. J. (2018) · Molecular Oral Microbiology · doi:10.1111/omi.12238 · Cited by 28
Metadata
- Authors
- Silverman, J. M., Brunet, Y. R., Cascales, E., & Mougous, J. D.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2012-10-13
- Volume
- 66
- Issue
- 1
- Pages
- 453-472
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2137087452
- Cited by
- 402
- References
- 3
- FWCI
- 1.45
- Type
- journal article
- Language
- en
- Open access
- green
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