The DOI matches its Crossref record; 151 of the 151 references it cites were found in a registry or an index.
Critical-Period Plasticity in the Visual Cortex
Open accessAbstract
In many regions of the developing brain, neuronal circuits undergo defined phases of enhanced plasticity, termed critical periods. Work in the rodent visual cortex has led to important insights into the cellular and molecular mechanisms regulating the timing of the critical period. Although there is little doubt that the maturation of specific inhibitory circuits plays a key role in the opening of the critical period in the visual cortex, it is less clear what puts an end to it. In this review, we describe the established mechanisms and point out where more experimental work is needed. We also show that plasticity in the visual cortex is present well before, and long after, the peak of the critical period.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“It is now well established, largely from studies in rodent primary visual cortex, that the maturation of GABAergic inhibition mediated by a fast-spiking PV interneuron network is a crucial mechanism for triggering the onset and regulating the progression of the critical period for functional wiring in V1 (16,46).”
From MeCP2 regulates the timing of critical period plasticity that shapes functional connectivity in primary visual cortex (2015) · cites this paper as [46]
In the citing paper
“After eye opening, visual experience further refines and elaborates circuits that are critical for normal visual function.”
From Role of emergent neural activity in visual map development (2014) · cites this paper as [7]
In the citing paper
“Though visual experience has a clear role in directing the refinement of synaptic connectivity [7]”
From Role of emergent neural activity in visual map development (2014) · cites this paper as [7]
Citations
Cites
Receptive fields, binocular interaction and functional architecture in the cat’s visual cortex
Hubel, D. H., & Wiesel, T. N. (1962) · The Journal of Physiology · doi:10.1113/jphysiol.1962.sp006837 · Cited by 13,680
The period of susceptibility to the physiological effects of unilateral eye closure in kittens
Hubel, D. H., & Wiesel, T. N. (1970) · The Journal of Physiology · doi:10.1113/jphysiol.1970.sp009022 · Cited by 3,030
Model of autism: increased ratio of excitation/inhibition in key neural systems
Rubenstein, J. L. R., & Merzenich, M. M. (2003) · Genes, Brain and Behavior · doi:10.1034/j.1601-183x.2003.00037.x · Cited by 2,768
SINGLE-CELL RESPONSES IN STRIATE CORTEX OF KITTENS DEPRIVED OF VISION IN ONE EYE
Wiesel, T. N., & Hubel, D. H. (1963) · Journal of Neurophysiology · doi:10.1152/jn.1963.26.6.1003 · Cited by 2,628
Driving fast-spiking cells induces gamma rhythm and controls sensory responses
Cardin, J. A., Carlén, M., Meletis, K., Knoblich, U., Zhang, F., Deisseroth, K., Tsai, L.-H., & Moore, C. I. (2009) · Nature · doi:10.1038/nature08002 · Cited by 2,603
Neocortical excitation/inhibition balance in information processing and social dysfunction
Yizhar, O., Fenno, L. E., Prigge, M., Schneider, F., Davidson, T. J., O’Shea, D. J., Sohal, V. S., Goshen, I., Finkelstein, J., Paz, J. T., et al. (2011) · Nature · doi:10.1038/nature10360 · Cited by 2,454
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
Tian, L., Hires, S. A., Mao, T., Huber, D., Chiappe, M. E., Chalasani, S. H., Petreanu, L., Akerboom, J., McKinney, S. A., Schreiter, E. R., et al. (2009) · Nature Methods · doi:10.1038/nmeth.1398 · Cited by 1,967
Experience-dependent structural synaptic plasticity in the mammalian brain
Holtmaat, A., & Svoboda, K. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2699 · Cited by 1,934
The development and application of optogenetics
Fenno, L., Yizhar, O., & Deisseroth, K. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113817 · Cited by 1,822
Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex
Pizzorusso, T., Medini, P., Berardi, N., Chierzi, S., Fawcett, J. W., & Maffei, L. (2002) · Science · doi:10.1126/science.1072699 · Cited by 1,679
Research works printed but not linked: 4
- Heinroth O. 1910. Beiträge zur Biologie, namentlich Ethologie und Psychologie der Anatiden. In Verhandlungen des V. Internationalen Ornitologen-Kongresses, Berlin , ed. H Schalow, pp. 589–702. Berlin: Deutsche Ornithologische Gesellschaft
- Joliot AH, 1991, New Biol., 3, 1121
- Nottebohm F, 1978, Serinus canarius, 46, 298
- Van LC, 1996, Gene Expr., 5, 245
Cited by
Sorted by citations
Items 401–417 of 417
Martinez, M. (2025) · theses.fr (ABES) · doi:10.70675/d05e33fcz2cd4z45d4zbe74z5e57fadd4292
Marco, I. D., Sansevero, G., Berardi, N., & Sale, A. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.13.718078
The calcium-binding protein S100β regulates synaptic plasticity in the visual cortex
Inglebert, Y., Sanz-Gálvez, R., & Kolta, A. (2026) · iScience · doi:10.1016/j.isci.2026.115793
Severín, D., & Kirkwood, A. (2026) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2026.1819500
LayerLock: Non-Collapsing Representation Learning with Progressive Freezing
Erdogan, G., Parthasarathy, N., Ionescu, C., Hudson, D. A., Lerchner, A., Zisserman, A., Sajjadi, M. S. M., & Carreira, J. (2025) · IEEE/CVF International Conference on Computer Vision (ICCV) · doi:10.1109/iccv51701.2025.01809
Experience-dependent critical period for synaptic plasticity in the rat olfactory amygdala
Aburto, B., Fernández‐Aburto, P., Mpodozis, J., Bacigalupo, J., & Sanhueza, M. (2026) · Frontiers in Synaptic Neuroscience · doi:10.3389/fnsyn.2026.1779075
Umeshima, H., Hirayama, T., Adachi, R., & Tomita, K. (2026) · Gene Expression Patterns · doi:10.1016/j.gep.2026.119412
The Critical Period Microbiota Shape Brain PlasticityPreprint
Damiani, F., Ashtiani, K. C., Tognozzi, A., Abdelkarim, S., Cornuti, S., Caldarelli, M., Baldi, P., & Tognini, P. (2026) · Research Square · doi:10.64898/2026.06.08.730811
Early Vision Shapes Recurrent Processing in the Human Visual CortexPreprint
Heitmann, C., Zhan, M., Linke, M., Kekunnaya, R., van Hoof, R., Goebel, R., & Roeder, B. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.06.16.731263
Rydzenska, N. D., Winklewski, P. J., Błaszczyk-Niezgoda, M., & Marcinkowska, A. B. (2026) · arXiv (Cornell University) · doi:10.48550/arxiv.2607.29068
Zhang, Y., Qiu, Z., Chen, T., Todo, Y., & Tang, Z. (2026) · Electronics · doi:10.3390/electronics15163516
Ren, Y., Liu, S., Liu, Y., Wang, D., Rong, J., Li, W., Zheng, C., Xu, L., Li, J., Wang, Z., et al. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1888954
Neuroplasticity under constraint: From sensory ecology to neuroinflammation
Diniz, D. G., Bento-Torres, N. V. O., Bento‐Torres, J., Jardim, N. Y. V., Sosthenes, M. C. K., Krejčová, L. V., dos Santos, Z. A., de Sousa, A. A., da Costa, E. R., Pereira, P. D. C., et al. (2026) · Brain Behavior and Immunity Integrative · doi:10.1016/j.bbii.2026.100199
Gurgone, A. (2020) · Institutional Research Information System University of Turin (University of Turin)
Characterisation of Endogenous Positive Allosteric Modulators of the Tropomyosin Receptor Kinase B
Hansen, M. (2026) · UTUPub (University of Turku)
Jaepel, J., Tepohl, C., Satterfield, R., & Fitzpatrick, D. (2026) · Current Biology · doi:10.1016/j.cub.2026.09.026
The role of fast-spiking interneurons in cortical map plasticity
Albieri, G. (2013)
Metadata
- Authors
- Levelt, C. N., & Hübener, M.
- Affiliations
- Netherlands Institute for Neuroscience (NL)
- Max Planck Society (DE)
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 2012-07-21
- Volume
- 35
- Issue
- 1
- Pages
- 309-330
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2100171700
- Cited by
- 402
- References
- 151
- Citations by year
- 2026: 23 · 2025: 32 · 2024: 25 · 2023: 18 · 2022: 27 · 2021: 25 · 2020: 31 · 2019: 20 · 2018: 40 · 2017: 34 · 2016: 22 · 2015: 37 · 2014: 35 · 2013: 23 · 2012: 9
- FWCI
- 2.55
- Type
- journal article
- Language
- en
- Open access
- green
- zenodo.org
- Licence
- other-oa
- Locations
- Annual Review of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- KNAW Research Portal (The Royal Netherlands Academy of Arts and Sciences) (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- KNAW research portal (Royal Academy of Art and Sciences (KNAW)) (submittedVersion)
- MPG.PuRe (Max Planck Society) (submittedVersion)
- Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, other-oa)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- critical period, critical period plasticity, visual cortex, cortical development, inhibitory circuits, neuronal maturation
- MeSH terms
- Aging, Animals, Critical Period, Psychological, Humans, Models, Neurological, Neural Inhibition, Synaptic Transmission, Neuronal Plasticity, Visual Cortex, Signal Transduction, Dominance, Ocular
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
