The DOI matches its Crossref record; 267 of the 267 references it cites were found in a registry or an index.
Skeletal Muscle Degenerative Diseases and Strategies for Therapeutic Muscle Repair
Abstract
Skeletal muscle is a highly specialized, postmitotic tissue that must withstand chronic mechanical and physiological stress throughout life to maintain proper contractile function. Muscle damage or disease leads to progressive weakness and disability, and manifests in more than 100 different human disorders. Current therapies to treat muscle degenerative diseases are limited mostly to the amelioration of symptoms, although promising new therapeutic directions are emerging. In this review, we discuss the pathological basis for the most common muscle degenerative diseases and highlight new and encouraging experimental and clinical opportunities to prevent or reverse these afflictions.
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“Several groups have reported successful replenishment of the stem cell pool by satellite cell transplantation into dystrophic or irradiated/injured muscles in mice120,139,140, although the rarity of satellite cells in muscle tissue has been a challenge for translating muscle stem cell transplantation to clinical practice141”
From Stem cell aging: mechanisms, regulators and therapeutic opportunities (2014) · cites this paper as [141]
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Metadata
- Authors
- Tabebordbar, M., Wang, E. T., & Wagers, A. J.
- Affiliations
- Harvard University (US)
- Howard Hughes Medical Institute (US)
- Corresponding author
- Wagers, Amy J.
- Venue
- Annual Review of Pathology: Mechanisms of Disease
- Publisher
- Annual Reviews
- Published
- 2013-01-24
- Volume
- 8
- Issue
- 1
- Pages
- 441-475
- ISSN
- 1553-4006 (ISSN-L)
- 1553-4014
- OpenAlex
- W2108059602
- Cited by
- 79
- References
- 267
- Citations by year
- 2026: 5 · 2025: 7 · 2024: 2 · 2023: 8 · 2022: 4 · 2021: 9 · 2020: 7 · 2019: 6 · 2018: 6 · 2017: 6 · 2016: 5 · 2015: 3 · 2014: 8 · 2013: 3
- FWCI
- 0.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Pathology Mechanisms of Disease (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Medicine › Genetics (clinical) › Neurogenetic and Muscular Disorders Research
- Health Sciences › Medicine › Rheumatology › Inflammatory Myopathies and Dermatomyositis
- Keywords
- muscle repair, muscle damage, muscle weakness, treatment options, muscle regeneration
- MeSH terms
- Animals, Humans, Muscular Diseases, Muscular Dystrophies, Muscle, Skeletal
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