The DOI matches its Crossref record; 165 of the 165 references it cites were found in a registry or an index.
Tuberculosis Pathogenesis and Immunity
Abstract
Despite the development of potentially curative chemotherapy, tuberculosis (TB) continues to cause increasing worldwide morbidity and is a leading cause of human mortality in the developing world. Recent advances in bacterial molecular genetics, immunology, and human genetics have yielded insight into the molecular determinants of virulence, the immune responses that are essential for restricting progressive disease, and the determinants of immunopathology in TB. Despite these advances, a large knowledge gap still exists that limits the development and testing of new interventions, including novel drugs and efficacious vaccines. This review focuses on our current knowledge of TB pathogenesis and immunity that has been derived from in vitro and in vivo studies. In addition, it highlights topics that need to be better understood to provide improved means of controlling TB worldwide.
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Self-citationLipid Metabolism in Regulation of Macrophage Functions
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Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids
Cambier, C. J., Takaki, K. K., Larson, R. P., Hernandez, R. E., Tobin, D. M., Urdahl, K. B., Cosma, C. L., & Ramakrishnan, L. (2014) · Nature · doi:10.1038/nature12799 · Cited by 480
Manzanillo, P. S., Shiloh, M. U., Portnoy, D. A., & Cox, J. S. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.03.007 · Cited by 473
γδ T cells: origin and fate, subsets, diseases and immunotherapy
Hu, Y., Hu, Q., Li, Y., Lu, L., Xiang, Z., Yin, Z., Kabelitz, D., & Wu, Y. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01653-8 · Cited by 382
Metadata
- Authors
- Philips, J. A., & Ernst, J. D.
- Venue
- Annual Review of Pathology: Mechanisms of Disease
- Publisher
- Annual Reviews
- Published
- 2012-02-28
- Volume
- 7
- Issue
- 1
- Pages
- 353-384
- ISSN
- 1553-4006 (ISSN-L)
- 1553-4014
- OpenAlex
- W2102806888
- Cited by
- 416
- References
- 165
- FWCI
- 3.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Philips, J. A., & Ernst, J. D. (2012). Tuberculosis Pathogenesis and Immunity. Annual Review of Pathology: Mechanisms of Disease. https://doi.org/10.1146/annurev-pathol-011811-132458
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
