The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.
Lipid Metabolism in Regulation of Macrophage Functions
Abstract
Macrophages are cells of the innate immune system that regulate the maintenance of tissue homeostasis, host defense during pathogen infection, and tissue repair in response to tissue injury. Recent studies indicate that macrophage functions are influenced by cellular metabolism, including lipid metabolism. Here, we review how macrophage lipid metabolism can be dynamically altered in different physiological and pathophysiological contexts and the key regulators involved. We also describe how alterations in lipid metabolism are integrated with the signaling pathways that specify macrophage functions, allowing for coordinated control of macrophage biology. Finally, we discuss how dysregulated lipid metabolism contributes to perturbed macrophage functions in settings such as atherosclerosis and pathogen infections.
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Cites
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Metabolism, metabolites, and macrophages in cancer
Li, M., Yang, Y., Xiong, L., Jiang, P., Wang, J., & Li, C. (2023) · Journal of Hematology & Oncology · doi:10.1186/s13045-023-01478-6 · Cited by 507
Lipid-loaded macrophages as new therapeutic target in cancer
Marelli, G., Morina, N., Portale, F., Pandini, M., Iovino, M., Di Conza, G., Ho, P.-C., & Di Mitri, D. (2022) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2022-004584 · Cited by 69
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Metadata
- Authors
- Yan, J., & Horng, T.
- Venue
- Trends in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2020-12
- Volume
- 30
- Issue
- 12
- Pages
- 979-989
- ISSN
- 0962-8924 (ISSN-L)
- OpenAlex
- W3091956344
- Cited by
- 553
- References
- 90
- FWCI
- 6.87
- Type
- journal article
- Language
- en
- Open access
- closed
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
