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Smoking, Mental Illness, and Public Health
Open accessAbstract
Tobacco use remains the leading preventable cause of death worldwide. In particular, people with mental illness are disproportionately affected with high smoking prevalence; they account for more than 200,000 of the 520,000 tobacco-attributable deaths in the United States annually and die on average 25 years prematurely. Our review aims to provide an update on smoking in the mentally ill. We review the determinants of tobacco use among smokers with mental illness, presented with regard to the public health HAVE framework of “the host” (e.g., tobacco user characteristics), the “agent” (e.g., nicotine product characteristics), the “vector” (e.g., tobacco industry), and the “environment” (e.g., smoking policies). Furthermore, we identify the significant health harms incurred and opportunities for prevention and intervention within a health care systems and larger health policy perspective. A comprehensive effort is warranted to achieve equity toward the 2025 Healthy People goal of reducing US adult tobacco use to 12%, with attention to all subgroups, including smokers with mental illness.
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“In fact, people with mental illness have so far not clearly benefitted from the recent reductions in tobacco smoking rates observed in the general population across Western societies 97 .”
From A meta-review of "lifestyle psychiatry": the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders (2020) · cites this paper as [97]
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“36 37-39 The current study aligns with this literature and suggests that ITQL ’ s tailored messaging appealed to and/or motivated individuals with a history of a mental health diagnosis to report quitting readiness.”
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Mental Health Symptoms as a Predictor of E-Cigarette Initiation Among Youth and Young Adults
Williams, K. N., Dimaya, B., McKay, T. L., Aseltine, M., Do, E. K., Hair, E. C., & Rath, J. M. (2026) · Health Education & Behavior · doi:10.1177/10901981261425265
“…the cycle starts again, thus giving the perception that nicotine has positive psychological benefits and is helping, not harming, youth’s mental health (Center for Disease Control and Prevention, 2022; Lynch & Bonnie, 1994; McLaughlin et al., 2015; Prochaska et al., 2017; Tidey et al., 2018).”
Bennett, M. E., Dickerson, F., Cha, S., Brandler, B. J., Lucksted, A. A., Medoff, D. R., Marano, C. M., Knight, S., & Graham, A. L. (2026) · Psychiatric Services · doi:10.1176/appi.ps.20250326
Approche thérapeutique et cognitive chez les patients souffrant d'une addiction au tabac
Vanderkam, P. (2023) · theses.fr (ABES) · doi:10.70675/307f9e53z9985z46a6z8c9dz1701c02f2849
Küçükaksu, M. H., Hoekstra, T., Vermeulen, J. M., Jansen, L., Helmig, S., van Meijel, B., & Adriaanse, M. C. (2026) · Psychological Medicine · doi:10.1017/s0033291726104516
Chapter 1. Trends in and Harms From Cigarette Smoking
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E-cigarette use among adults in southern Iran: a qualitative study
Rastegar, Y., Kakhaki, H. E. S., Abolghaseminejad, P., Dadipoor, S., Yari, A., & Kalan, M. E. (2026) · BMC Public Health · doi:10.1186/s12889-026-27917-w
“Withdrawal symptoms commonly include irritability, anxiety, depressive mood, and sleep disturbances [12].”
Williams, P. P., Huddlestone, L., Shoesmith, E., Sweetman, J., Stevens, H., Mitchell, A., Wiggins, F., Sinclair, L., Exley, V., Hewitt, C., et al. (2026) · Addiction · doi:10.1111/add.70519
“Tobacco smoking is a leading cause of preventable death and disease and was responsible for 7.7 million deaths globally in 2019 [1], with a disproportionate burden on individuals with mental health conditions [2, 3].”
InfluentialWearable physiological signals and relapse status during smoking cessation: a pilot study
Shoshina, I. I., Santos, N. A., Fernandes, T. P., Horvathova, M., & Strandberg, L. (2026) · Journal of Addictive Diseases · doi:10.1080/10550887.2026.2680436
Sawyer, C. S., Hassan, L., Torous, J. B., Bucci, S., Crane, D., Sainsbury, J., Warrender, E., Gilbody, S. M., Lovell, K., & Firth, J. (2026) · Journal of Mental Health · doi:10.1080/09638237.2026.2672338
“Engaging individuals who are not yet ready to change remains a key challenge, as seen in our study and echoed across DHIs and smoking cessation literature (Lipschitz et al., 2023; Prochaska et al., 2017).”
Alsaab, S., Newnham, M., Turner, A. M., Aldossary, H. S., Albukhary, A., & Farley, A. (2026) · BMJ Open Respiratory Research · doi:10.1136/bmjresp-2025-003977
“Of 74–76 However, in the small number of studies that provided adjusted outcomes (including those that adjusted for smoking), the relationship between mental health conditions and outcomes largely remained, suggesting that these factors alone do not explain the association.”
Carney-Knisely, G., Ferketich, A. K., Singh, P., Gur, T., & Padamsee, T. J. (2026) · Journal of Health Psychology · doi:10.1177/13591053261461883
Fukasawa, M., Usuda, K., Kataoka, M., & Kuroda, N. (2026) · Psychiatry Research · doi:10.1016/j.psychres.2026.117392
Neuropharmacology of Nicotine Addiction and Therapeutic Strategies for Smoking Cessation
Hefny, A. A., Karuturi, R. C., Kalyaanamoorthy, S., Rao, P. P. N., & Ganesan, A. (2026) · Biology · doi:10.3390/biology15161412
Ribeiro, M. D., Giguère, C., & Cailhol, L. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1726738
Yıldırım, E. A., & Yıldırım, Y. E. (2026) · Archives of Dermatological Research · doi:10.1007/s00403-026-04756-8
Obesity and poor sleep quality – prevalences and risk factors from the LIFE-Adult-Study
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“This may indicate a close relationship with shared underlying factors between smoking and mental health, as individuals with psychological conditions are more likely to engage in smoking behavior 49 . www.nature.com/scientificreports”
Japuntich, S. J., Adkins-Hempel, M., Sacasa, N. G., Lundtvedt, C., Becker, S. J., Helseth, S. A., Pratt, R. J., Tidey, J. W., DUNSIGER, S. I., Evins, A. E., et al. (2026) · Community Mental Health Journal · doi:10.1007/s10597-026-01727-1
Adeniji, F. I. P., Foster, J. D., Ni, W., Mallory, V., Ogunnaike, A., Pei, D., Kodriati, N., Petillo, S. L., Henderson, K. C., Juris, A. J., et al. (2026) · Tobacco Use Insights · doi:10.1177/1179173x261484361
Smoking cessation during addiction recovery does not increase relapse risk
Frazer, K. (2026) · Evidence-Based Nursing · doi:10.1136/ebnurs-2025-104452
Tobacco Use Disorder and Co-Occurring Mental Health Conditions
Kelly, M. M., Karekla, M., & Heffner, J. L. (2026) · The Journal of Nervous and Mental Disease · doi:10.1097/nmd.0000000000001877
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van Grondelle, K. C., Túnez, A., Pasman, J. A., Wouda, M. A. E., Wesseldijk, L. W., Lin, B. D., Goula, A. A., Verweij, K. J. H., & Luykx, J. J. (2026) · medRxiv · doi:10.64898/2026.09.28.26364160
Substance Abuse Among University Students in Iran and Associated Factors: A Comprehensive Review
Imani‐Goghary, Z., Beigmoradi, S., Firouzabadi, M., & Pourramezani, N. (2026) · Social medicine · doi:10.71164/socialmedicine.v19i3.2026.2203
Goulbourne, T. D., Leal, I. M., Britton, M., Chen, T. A., Bergey, A. E., Siddiqi, A. D., Williams, T., Casey, K., & Reitzel, L. R. (2026) · Healthcare · doi:10.3390/healthcare14203482
“Tobacco cessation is associated with a 25% increase in sobriety among people receiving treatment for substance use disorder [25,26], and smoking cessation, in particular, is associated with decreases in reported anxiety, depression, and stress [25,27].”
Metadata
- Authors
- Prochaska, J. J., Das, S., & Young-Wolff, K. C.
- Affiliations
- Stanford Medicine (US)
- Stanford University (US)
- Division of Research, Kaiser Permanente Northern California, Oakland, California 94612;
- Venue
- Annual Review of Public Health
- Publisher
- Annual Reviews
- Published
- 2017-03-20
- Volume
- 38
- Issue
- 1
- Pages
- 165-185
- ISSN
- 0163-7525 (ISSN-L)
- 1545-2093
- PMC
- PMC5788573
- OpenAlex
- W2520553955
- Cited by
- 503
- References
- 135
- Citations by year
- 2026: 34 · 2025: 51 · 2024: 61 · 2023: 74 · 2022: 70 · 2021: 92 · 2020: 51 · 2019: 36 · 2018: 21 · 2017: 13
- FWCI
- 2.74
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Annual Review of Public Health (publishedVersion, cc-by-sa)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion, cc-by-sa)
- PubMed Central (acceptedVersion, cc-by-sa)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL117736)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Global Public Health Policies and Epidemiology
- Keywords
- tobacco use, mental illness, smoking prevalence, premature mortality, determinants of tobacco use, nicotine products, tobacco industry, smoking policy, smoking prevention, smoking cessation interventions, health equity, tobacco use reduction
- MeSH terms
- Mental Disorders, Health Policy, Humans, Public Health, Smoking, United States, Comorbidity, Smoking Cessation, Persons with Psychiatric Disorders
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