The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS
Abstract
Voltage-gated ion channels are responsible for generation of electrical signals in cell membranes. Their principal subunits are members of a gene family and can function as voltage-gated ion channels by themselves. They are expressed in association with one or more auxiliary subunits which increase functional expression and modify the functional properties of the principal subunits. Structural elements that are required for voltage-dependent activation, selective ion conductance, and inactivation have been identified, and their mechanisms of action are being explored through mutagenesis, expression in heterologous cells, and functional analysis. These experiments reveal that this family of channels is built upon a common structural theme with variations appropriate for functional specialization of each channel type.
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Citations
Cites
Calcium channel characteristics conferred on the sodium channel by single mutations
Heinemann, S. H., Terlau, H., Stühmer, W., Imoto, K., & Numa, S. (1992) · Nature · doi:10.1038/356441a0 · Cited by 784
Cited by
Structure and Regulation of Voltage-Gated Ca 2+ Channels
Catterall, W. A. (2000) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.16.1.521 · Cited by 2,344
Self-citationResurgence of sodium channel research
Goldin, A. L. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.871 · Cited by 688
Bech-Hansen, N. T., Naylor, M. J., Maybaum, T. A., Pearce, W. G., Koop, B., Fishman, G. A., Mets, M., Musarella, M. A., & Boycott, K. M. (1998) · Nature Genetics · doi:10.1038/947 · Cited by 517
Dib-Hajj, S. D., Tyrrell, L., Black, J. A., & Waxman, S. G. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.15.8963 · Cited by 503
Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist
Ahuja, S., Mukund, S., Deng, L., Khakh, K., Chang, E., Ho, H., Shriver, S., Young, C., Lin, S., Johnson, J. P., et al. (2015) · Science · doi:10.1126/science.aac5464 · Cited by 319
Metadata
- Authors
- Catterall, W. A.
- Venue
- Annual Review of Biochemistry
- Publisher
- Annual Reviews
- Published
- 1995-06
- Volume
- 64
- Issue
- 1
- Pages
- 493-531
- ISSN
- 0066-4154 (ISSN-L)
- 1545-4509
- OpenAlex
- W2172530119
- Cited by
- 948
- References
- 1
- FWCI
- 26.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS. https://app.cochat.ai/papers/10.1146/annurev.bi.64.070195.002425
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- Catterall, W. A. (1995). STRUCTURE AND FUNCTION OF VOLTAGE-GATED ION CHANNELS. Annual Review of Biochemistry. https://doi.org/10.1146/annurev.bi.64.070195.002425
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
