The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Particle-Tracking Microrheology of Living Cells: Principles and Applications
Abstract
A multitude of cellular and subcellular processes depend critically on the mechanical deformability of the cytoplasm. We have recently introduced the method of particle-tracking microrheology, which measures the viscoelastic properties of the cytoplasm locally and with high spatiotemporal resolution. Here we establish the basic principles of particle-tracking microrheology, describing the advantages of this approach over more conventional approaches to cell mechanics. We present basic concepts of molecular mechanics and polymer physics relevant to the microrheological response of cells. Particle-tracking microrheology can probe the mechanical properties of live cells in experimentally difficult, yet more physiological, environments, including cells embedded inside a 3D matrix, adherent cells subjected to shear flows, and cells inside a developing embryo. Particle-tracking microrheology can readily reveal the lost ability of diseased cells to resist shear forces.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Matrix elasticity directs stem cell lineage specification
Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382
Rapid leukocyte migration by integrin-independent flowing and squeezing
Lämmermann, T., Bader, B. L., Monkley, S. J., Worbs, T., Wedlich-Söldner, R., Hirsch, K., Keller, M., Förster, R., Critchley, D. R., Fässler, R., et al. (2008) · Nature · doi:10.1038/nature06887 · Cited by 1,397
Regulation of mitochondria distribution by RhoA and formins
Minin, A. A., Kulik, A. V., Gyoeva, F. K., Li, Y., Goshima, G., & Gelfand, V. I. (2006) · Journal of Cell Science · doi:10.1242/jcs.02762 · Cited by 102
Cited by
Actin Dynamics, Architecture, and Mechanics in Cell Motility
Blanchoin, L., Boujemaa-Paterski, R., Sykes, C., & Plastino, J. (2014) · Physiological Reviews · doi:10.1152/physrev.00018.2013 · Cited by 1,457
Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts
Stewart, M. P., Langer, R., & Jensen, K. F. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00678 · Cited by 747
Michalet, X. (2010) · Physical Review E · doi:10.1103/physreve.82.041914 · Cited by 721
Cell mechanics: principles, practices, and prospects
Moeendarbary, E., & Harris, A. R. (2014) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1275 · Cited by 342
Optical tweezers — from calibration to applications: a tutorial
Gieseler, J., Gomez-Solano, J. R., Magazzù, A., Pérez Castillo, I., Pérez García, L., Gironella-Torrent, M., Viader-Godoy, X., Ritort, F., Pesce, G., Arzola, A. V., et al. (2021) · Advances in Optics and Photonics · doi:10.1364/aop.394888 · Cited by 282
Metadata
- Authors
- Wirtz, D.
- Venue
- Annual Review of Biophysics
- Publisher
- Annual Reviews
- Published
- 2009-06-01
- Volume
- 38
- Issue
- 1
- Pages
- 301-326
- ISSN
- 1936-122X (ISSN-L)
- 1936-1238
- OpenAlex
- W2161346554
- Cited by
- 670
- References
- 4
- FWCI
- 1.61
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Particle-Tracking Microrheology of Living Cells: Principles and Applications. https://app.cochat.ai/papers/10.1146/annurev.biophys.050708.133724
- The paper
- Wirtz, D. (2009). Particle-Tracking Microrheology of Living Cells: Principles and Applications. Annual Review of Biophysics. https://doi.org/10.1146/annurev.biophys.050708.133724
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
