Cited by 370Cardiomyopathy and Myosin StudiesCellular Mechanics and InteractionsMicrotubule and mitosis dynamics

The DOI matches its Crossref record.

Unconventional Myosins

Mooseker, Mark S., Cheney, Richard E.·1995·Annual Review of Cell and Developmental Biology

Open this paper in CoChat — free account

Abstract

Myosins are molecular motors that upon interaction with actin filaments convert energy from ATP hydrolysis into mechanical force. Evidence has emerged for the existence of a large, widely expressed and evolutionarily ancient superfamily of myosin genes. In addition to the well-catheterized conventional, filament-forming, two-headed myosin-II of muscle and nonmuscle cells, at least ten additional classes of myosins have been identified. In vertebrates, at least seven of the eleven classes are expressed, and many myosins can be expressed in a single cell type. This review summarizes known structural and functional features of these novel unconventional myosins.

Integrity signals

Registry

Crossref · 10.1146/annurev.cb.11.110195.003221

Cites

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Sorted by citations

Items 101–200 of 369

Microtubule-Microfilament Synergy in the Cytoskeleton
Gavin, R. H. (1997) · International review of cytology · doi:10.1016/s0074-7696(08)62478-x · Cited by 83
Myosin-IXb Is a Single-headed and Processive Motor
Post, P. L., Tyska, M. J., O’Connell, C. B., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111173200 · Cited by 83
Self-citation
Brain Myosin-V, a Calmodulin-carrying Myosin, Binds to Calmodulin-dependent Protein Kinase II and Activates Its Kinase Activity
Costa, M. C. R., Mani, F., Santoro, W., Espreáfico, E. M., & Larson, R. E. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.22.15811 · Cited by 83
Cloning and Characterization of a Novel RING Finger Protein That Interacts with Class V Myosins
El-Husseini, A., & Vincent, S. R. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.28.19771 · Cited by 83
Constitutive Activation of Endocytosis by Mutation ofmyoA, the Myosin I Gene of Aspergillus nidulans
Yamashita, R. A., & May, G. S. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.23.14644 · Cited by 80
The Prooncoprotein EWS Binds Calmodulin and Is Phosphorylated by Protein Kinase C through an IQ Domain
Deloulme, J., Prichard, L. B., Delattre, O., & Storm, D. R. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.43.27369 · Cited by 77
p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I
Brzeska, H., Knaus, U. G., Wang, Z.-Y., Bokoch, G., & Korn, E. D. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1092 · Cited by 79
A role for myosin-1A in the localization of a brush border disaccharidase
Tyska, M. J., & Mooseker, M. S. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200310031 · Cited by 79
“M1A was discovered as the first vertebrate class I myosin over a decade ago (Cheney and Mooseker, 1992); the investigation we present here is the first to define a specific function for this motor.”
BackgroundSelf-citation
The predominant defect in dilute melanocytes is in melanosome distribution and not cell shape, supporting a role for myosin V in melanosome transport
Wei, Q., Wu, X., & Hammer, J. A. (1997) · Journal of Muscle Research and Cell Motility · doi:10.1023/a:1018659117569 · Cited by 79
Myosins: matching functions with motors
Baker, J. P., & Titus, M. A. (1998) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(98)80089-6 · Cited by 78
Both Calmodulin and the Unconventional Myosin Myr4 Regulate Membrane Trafficking Along the Recycling Pathway of MDCK Cells
Huber, L. A., Fialka, I., Paiha, K., Hunziker, W., Sacks, D. B., Bähler, M., Way, M., Gagescu, R., & Gruenberg, J. E. (2000) · Traffic · doi:10.1034/j.1600-0854.2000.010607.x · Cited by 76
“This new superfamily encompasses 14 groups of so-called unconventional myosins (24,25), but the precise function of most of these proteins is unknown.”
Background
Regulation of Dictyostelium Myosin I and II
de la Roche, M. A., & Côté, G. P. (2001) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/s0304-4165(01)00110-6 · Cited by 75
Motor Function and Regulation of Myosin X
Homma, K., Saito, J., Ikebe, R., & Ikebe, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m104785200 · Cited by 74
RETRACTED: Arabidopsis myosin XI mutant is defective in organelle movement and polar auxin transport
Holweg, C., & Nick, P. A. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403155101 · Cited by 74
Retracted
Molecular and functional characteristics of MAP-2a: Ability of MAP-2a versus MAP-2b to induce stable microtubules in COS cells
Kalcheva, N., Rockwood, J. M., Kress, Y., Steiner, A. M., & Shafit‐Zagardo, B. (1998) · Cell Motility and the Cytoskeleton · doi:10.1002/(sici)1097-0169(1998)40:3 · Cited by 35
Actin Dynamics Is Essential for Myosin-Based Transport of Membrane Organelles
Semenova, I., Burakov, A. V., Berardone, N., Zaliapin, I., Slepchenko, B. M., Svitkina, T., Kashina, A. S., & Rodionov, V. (2008) · Current Biology · doi:10.1016/j.cub.2008.08.070 · Cited by 72
α-Kinase 1, a New Component in Apical ProteinTransport
Heine, M., Cramm‐Behrens, C. I., Ansari, A., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m502265200 · Cited by 72
Engineering of the Myosin-Iβ Nucleotide-binding Pocket to Create Selective Sensitivity to N 6-modified ADP Analogs
Gillespie, P. G., Gillespie, S. K. H., Mercer, J. A., et al. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.44.31373 · Cited by 72
Brush Border Myosin–I Structure and ADP-dependent Conformational Changes Revealed by Cryoelectron Microscopy and Image Analysis
Jontes, J. D., & Milligan, R. A. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.3.683 · Cited by 72
“Thus, we are able to directly measure the full magnitude of the ADP-dependent tail swing.”
Background
DOC-2/DAB2 Is the Binding Partner of Myosin VI
Inoue, A., Sato, O., Homma, K., & Ikebe, M. (2002) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2002.6636 · Cited by 65
She4p/Dim1p Interacts with the Motor Domain of Unconventional Myosins in the Budding Yeast,Saccharomyces cerevisiae
Toi, H., Fujimura‐Kamada, K., Irie, K., Takai, Y., Todo, S., & Tanaka, K. (2003) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-09-0616 · Cited by 70
“They constitute a large superfamily of proteins implicated in diverse cellular functions (Mooseker and Cheney, 1995; Sellers, 1999).”
Background
The core of the motor domain determines the direction of myosin movement
Homma, K., Yoshimura, M., Saito, J., et al. (2001) · Nature · doi:10.1038/35090597 · Cited by 71
The Atypical Cadherin Dachsous Controls Left-Right Asymmetry in Drosophila
González‐Morales, N., Géminard, C., Lebreton, G., et al. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.04.026 · Cited by 70
“The conserved type IDmyosin gene (myosin ID, myoID; also known as myo31DF) (Mooseker and Cheney, 1995; Morgan et al., 1995) is unique, as myoID loss of function leads to complete situs inversus with all asymmetric organs developing as sinistral (Hozumi et al., 2006; Géminard et al., 2014; Spéder…”
Background
Drosophila crinkled, Mutations of Which Disrupt Morphogenesis and Cause Lethality, Encodes Fly Myosin VIIA
Kiehart, D. P., Franke, J. D., Chee, M. K., Montague, R. A., Chen, T.-L., Roote, J., & Ashburner, M. (2004) · Genetics · doi:10.1534/genetics.104.026369 · Cited by 70
Scanning Force Microscopy of the Interaction Events between a Single Molecule of Heavy Meromyosin and Actin
Nakajima, H., Kunioka, Y., Nakano, K., Shimizu, K., Seto, M., & Ando, T. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6612 · Cited by 70
Kinetic characterization of brush border myosin-I ATPase
Jontes, J. D., Milligan, R. A., Pollard, T. D., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.26.14332 · Cited by 69
A subclass of myosin XI is associated with mitochondria, plastids, and the molecular chaperone subunit TCP‐1α in maize
Wang, Z., & Pesacreta, T. C. (2004) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.10168 · Cited by 69
Highly Skewed X-Chromosome Inactivation Is Associated with Idiopathic Recurrent Spontaneous Abortion
Lanasa, M. C., Hogge, W. A., Kubik, C. J., Blancato, J. K., & Hoffman, E. P. (1999) · The American Journal of Human Genetics · doi:10.1086/302441 · Cited by 67
Cloning and Chromosomal Localization of a Human Class III Myosin
Dosé, A. C., & Burnside, B. (2000) · Genomics · doi:10.1006/geno.2000.6256 · Cited by 67
Cloning of the Genes Encoding Two Murine and Human Cochlear Unconventional Type I Myosins
Crozet, F., Amraoui, A. E., Blanchard, S., et al. (1997) · Genomics · doi:10.1006/geno.1996.4526 · Cited by 67
High Affinity Ca2+ Binding Sites of Calmodulin Are Critical for the Regulation of Myosin Iβ Motor Function
Zhu, T., Beckingham, K., & Ikebe, M. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.32.20481 · Cited by 66
DE-Cadherin regulates unconventional Myosin ID and Myosin IC in Drosophila left-right asymmetry establishment
Petzoldt, A. G., Coutelis, J., Géminard, C., et al. (2012) · Development · doi:10.1242/dev.047589 · Cited by 65
“The myoID gene encodes an unconventional type ID myosin: a one-headed, monomeric actinbased motor, bearing an N-terminal motor head domain, a neck domain with two IQ motifs and a short basic tail domain (Mooseker and Cheney, 1995).”
Background
The Myosin I SH3 Domain and TEDS Rule Phosphorylation Site are Required for In Vivo Function
Novak, K. D., & Titus, M. A. (1998) · Molecular Biology of the Cell · doi:10.1091/mbc.9.1.75 · Cited by 64
“Thus, the myosin Is have been proposed to play important roles in cell migration, endocytosis, and vesicle transport (Mooseker and Cheney, 1995; Ostap and Pollard, 1996b).”
Background
Cooperativity between the Two Heads of Rabbit Skeletal Muscle Heavy Meromyosin in Binding to Actin
Conibear, P. B., & Geeves, M. A. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77581-2 · Cited by 65
“Given the multitude of different myosins now identified and the potential for fine tuning (Mooseker and Cheney, 1995), it seems conceivable that such a mechanism might operate in other two-headed members of the myosin superfamily, most of which are yet to be characterized in detail with the possibility of processivity…”
Background
A novel myosin heavy chain gene in human chromosome 19q13.3
Leal, A., Endele, S. U., Stengel, C., et al. (2003) · Gene · doi:10.1016/s0378-1119(03)00613-9 · Cited by 63
A myosin family reunion
Sellers, J. R., Goodson, H. V., & Wang, F. (1996) · Journal of Muscle Research and Cell Motility · doi:10.1007/bf00140320 · Cited by 63
“The approach of Cheney and Mooseker (1992) was to give each protein or group of proteins that doesn’t clearly group on the basis of statistical tests with other proteins a new class name.”
BackgroundMethod
Myosins as fundamental components during tumorigenesis: diverse and indispensable
Li, Y.-R., & Yang, W. (2016) · Oncotarget · doi:10.18632/oncotarget.8800 · Cited by 64
The Tip of the Coiled-coil Rod Determines the Filament Formation of Smooth Muscle and Nonmuscle Myosin
Ikebe, M., Komatsu, S., Woodhead, J. L., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101969200 · Cited by 62
Myosin V in the brain: mutations lead to neurological defects
Langford, G. M., & Molyneaux, B. J. (1998) · Brain Research Reviews · doi:10.1016/s0165-0173(98)00020-4 · Cited by 61
Cellular and Molecular Mechanics of Gliding Locomotion in Eukaryotes
Heintzelman, M. B. (2006) · International review of cytology · doi:10.1016/s0074-7696(06)51003-4 · Cited by 60
Calcium Signalling in the Endothelium
Tran, Q., & Watanabe, H. (2006) · Springer eBooks · doi:10.1007/3-540-32967-6_5 · Cited by 59
Distinct functions of calmodulin are required for the uptake step of receptor‐mediated endocytosis in yeast: the type I myosin Myo5p is one of the calmodulin targets
Geli, M., Wesp, A., & Riezman, H. (1998) · The EMBO Journal · doi:10.1093/emboj/17.3.635 · Cited by 59
“(Kübler and Riezman, 1993; Raths et al., 1993; Bénédetti et al., 1994; Kübler et al., 1994; Munn et al., 1995; Geli and Riezman, 1996; Wendland et al., 1996; Wesp et al., 1997; Tang et al., 1997).”
Motor proteins: Myosin V – the multi-purpose transport motor
Titus, M. A. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00143-6 · Cited by 59
Myosin-II Tails Confer Unique Functions inSchizosaccharomyces pombe: Characterization of a Novel Myosin-II Tail
Bezanilla, M., & Pollard, T. D. (2000) · Molecular Biology of the Cell · doi:10.1091/mbc.11.1.79 · Cited by 58
“Myosin genes comprise a superfamily defined by their conserved catalytic domains (Mooseker and Cheney, 1995; Sellers et al., 1996).”
Critical and optimal Ig domains for promotion of neurite outgrowth by L1/Ng-CAM
Haspel, J. A., Friedlander, D. R., Ivgy-May, N., Chickramane, S., Roonprapunt, C., Chen, S., Schachner, M., & Grumet, M. (2000) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(20000215)42:3 · Cited by 61
Self-citation
Myosin V Colocalizes with Melanosomes and Subcortical Actin Bundles Not Associated with Stress Fibers in Human Epidermal Melanocytes
Lambert, J., Haeghen, Y. V., Vancoillie, G., Naeyaert, J. M., Onderwater, J. J. M., Koerten, H. K., & Mommaas, A. M. (1998) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1998.00395.x · Cited by 57
Regulation of molecular motor proteins
Reilein, A. R., Rogers, S. L., Tuma, M. C., & Gelfand, V. I. (2001) · International review of cytology · doi:10.1016/s0074-7696(01)04005-0 · Cited by 56
Screening for MYO15A gene mutations in autosomal recessive nonsyndromic, GJB2 negative Iranian deaf population
Fattahi, Z., Shearer, A. E., Babanejad, M., et al. (2012) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.34411 · Cited by 57
Myr 8, A Novel Unconventional Myosin Expressed during Brain Development Associates with the Protein Phosphatase Catalytic Subunits 1α and 1γ1
Patel, K. G., Liu, C., Cameron, P. L., & Cameron, R. S. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-20-07954.2001 · Cited by 56
“The putative neck domain contains a single region (CQKVIRGFLARQ, amino acids 1153–1164) similar to the IQ consensus sequence (IqxxxRGxxxRK), a region predicted to serve as the calmodulin/ light-chain binding site (Mooseker and Cheney, 1995; Houdusse et al., 1996).”
Background
Overlapping functions of myosin-I isoforms?
Ostap, E. M., & Pollard, T. D. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.133.2.221 · Cited by 57
Genetic variants in ACTN3 and MYO1H are associated with sagittal and vertical craniofacial skeletal patterns
Cunha, A. S., Nelson‐Filho, P., Marañón‐Vásquez, G. A., et al. (2018) · Archives of Oral Biology · doi:10.1016/j.archoralbio.2018.09.018 · Cited by 56
The Catalytic Domain of Acanthamoeba Myosin I Heavy Chain Kinase
Brzeska, H., Szczepanowska, J., Hoey, J. G., & Korn, E. D. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.43.27056 · Cited by 56
[1] Purification and assay of myosin V
Cheney, R. E. (1998) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(98)98003-x · Cited by 56
Self-citation
Unconventional myosins: new frontiers in actin-based motors
Titus, M. A. (1997) · Trends in Cell Biology · doi:10.1016/s0962-8924(97)01019-2 · Cited by 56
Coccidioides posadasii contains single chitin synthase genes corresponding to classes I to VII
Mandel, M. A., Galgiani, J. N., Kroken, S. B., et al. (2006) · Fungal Genetics and Biology · doi:10.1016/j.fgb.2006.05.005 · Cited by 55
“AoChsY is a class V CHS, and has a myosin motor-domain at its N-terminus with the characteristic Ploop, switches I and II, and the ATP domain (Hasson and Mooseker, 1995; Mooseker and Cheney, 1995; Rayment, 1996).”
Background
The Cloning and Developmental Expression of Unconventional Myosin IXA (MYO9A) a Gene in the Bardet–Biedl Syndrome (BBS4) Region at Chromosome 15q22–q23
Gorman, S. W., Haider, N. B., Grieshammer, U., et al. (1999) · Genomics · doi:10.1006/geno.1999.5867 · Cited by 55
Living markers for actin block myosin‐dependent motility of plant organelles and auxin
Holweg, C. (2006) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20164 · Cited by 55
A family of unconventional myosins from the nematode Caenorhabditis elegans
Baker, J. P., & Titus, M. A. (1997) · Journal of Molecular Biology · doi:10.1006/jmbi.1997.1232 · Cited by 55
motility and host cell invasiveness are drastically impaired by jasplakinolide, a cyclic peptide stabilizing F-actin
Poupel, O., & Tardieux, I. (1999) · Microbes and Infection · doi:10.1016/s1286-4579(99)80066-5 · Cited by 54
Unconventional Myosins, Actin Dynamics and Endocytosis: A Ménage à Trois?
Soldati, T. (2003) · Traffic · doi:10.1034/j.1600-0854.2003.t01-1-00095.x · Cited by 53
“At the moment, only two homologues of long-tailed ameboid class I myosins, myosin IE (16) and IF (17), have been described in mammals, but many examples of short-tailed myosins have been extensively investigated (18,19).”
Background
Structural studies on myosin II: Communication between distant protein domains
Gulick, A. M., & Rayment, I. (1997) · BioEssays · doi:10.1002/bies.950190707 · Cited by 49
Neuronal precursors of the adult rat subependymal zone persist into senescence, with no decline in spatial extent or response to BDNF
Goldman, S. A., Kirschenbaum, B., Harrison‐Restelli, C., & Thaler, H. T. (1997) · Journal of Neurobiology · doi:10.1002/(sici)1097-4695(19970605)32:6 · Cited by 81
Vertebrate Unconventional Myosins
Hasson, T., & Mooseker, M. S. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.28.16431 · Cited by 52
Self-citation
Biochemical and Immunocytochemical Characterization of Two Types of Myosins in Cultured Tobacco Bright Yellow-2 Cells
Yokota, E., Yukawa, C., Muto, S., et al. (1999) · PLANT PHYSIOLOGY · doi:10.1104/pp.121.2.525 · Cited by 51
The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac
Chen, L., Luo, S., Dupre, A., Vasoya, R. P., Parthasarathy, A., Aita, R., Malhotra, R., Hur, J., Toke, N. H., Chiles, E., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22761-5 · Cited by 46
Effects of Mutations in the γ-Phosphate Binding Site of Myosin on Its Motor Function
Li, X., Rhodes, T. E., Ikebe, R., et al. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.42.27404 · Cited by 50
A targeted gene silencing technique shows that Drosophila myosin VI is required for egg chamber and imaginal disc morphogenesis
Deng, W., Leaper, K., & Bownes, M. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.21.3677 · Cited by 50
The Novel Adaptor Protein, Mti1p, and Vrp1p, a Homolog of Wiskott-Aldrich Syndrome Protein-Interacting Protein (WIP), May Antagonistically Regulate Type I Myosins in Saccharomyces cerevisiae
Mochida, J., Yamamoto, T. G., Fujimura‐Kamada, K., & Tanaka, K. (2002) · Genetics · doi:10.1093/genetics/160.3.923 · Cited by 48
The growing family of myosin motors and their role in neurons and sensory cells
Hasson, T., & Mooseker, M. S. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80080-3 · Cited by 49
Self-citation
Possible Interaction between USH1B and USH3 Gene Products as Implied by Apparent Digenic Deafness Inheritance
Adato, A., Kalinski, H., Weil, D., Chaı̈b, H., Korostishevsky, M., & Bonné, B. (1999) · The American Journal of Human Genetics · doi:10.1086/302438 · Cited by 48
New Insights into the Role of the Cortical Cytoskeleton in Exocytosis from Neuroendocrine Cells
Gutiérrez, L. M. (2012) · International review of cytology · doi:10.1016/b978-0-12-394306-4.00009-5 · Cited by 48
Smitin, a novel smooth muscle titin–like protein, interacts with myosin filaments in vivo and in vitro
Kim, K., & Keller, T. C. S. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200107037 · Cited by 48
“We speculate that the three apparent forms of titin or titin-like proteins found in striated muscle, smooth muscle, and nonmuscle cells are encoded by distinct genes or gene families, as are the three major forms of myosin II found differentially expressed in striated muscle, smooth muscle, and nonmuscle cells (Goodso…”
Background
Human Myosin V Gene Produces Different Transcripts in a Cell Type-Specific Manner
Lambert, J., Naeyaert, J. M., Callens, T., et al. (1998) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1998.9644 · Cited by 47
ISOFORM SORTING AND THE CREATION OF INTRACELLULAR COMPARTMENTS
Gunning, P. W., Weinberger, R. P., Jeffrey, P. L., & Hardeman, E. C. (1998) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.14.1.339 · Cited by 47
Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected
Brinkley, B. R., & Goepfert, T. M. (1998) · Cell Motility and the Cytoskeleton · doi:10.1002/(sici)1097-0169(1998)41:4 · Cited by 152
Self-citation
A novel nonsense mutation in MYO6 is associated with progressive nonsyndromic hearing loss in a Danish DFNA22 family
Sanggaard, K. M., Kjaer, K. W., Eiberg, H., et al. (2008) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.32174 · Cited by 45
“The tail domain is hypothesized to be responsible for dimerization,membranebinding and to target the myosin to its particular subcellular location [Mooseker and Cheney, 1995; Hasson and Mooseker, 1996], and we therefore speculate that the functional effect of the p.R849X nonsense mutation might be…”
Background
Dual Regulation of Mammalian Myosin VI Motor Function
Yoshimura, M., Homma, K., Saito, J., Inoue, A., Ikebe, R., & Ikebe, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m105080200 · Cited by 45
Identification and Molecular Characterization of Myosin Gene Family in Oryza sativa Genome
Jiang, S., & Ramachandran, S. (2004) · Plant and Cell Physiology · doi:10.1093/pcp/pch061 · Cited by 44
“…be allocated into two subclasses based on a separate phylogenetic tree analysis using rice myosin head domain sequences (data not shown), similar to the subclasses of myosins observed in other plants (Kinkema and Schiefelbein 1994, Kinkema et al. 1994, Mooseker and Cheney 1995, Liu et al. 2001).”
MethodInfluential
[18] Studies of molecular motors using caged compounds
Dantzig, J. A., Higuchi, H., & Goldman, Y. E. (1998) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(98)91021-7 · Cited by 43
Mechanoenzymatic Characterization of Human Myosin Vb
Watanabe, S., Mabuchi, K., Ikebe, R., & Ikebe, M. (2006) · Biochemistry · doi:10.1021/bi051682b · Cited by 45
Identification and functional analysis of the gene for type I myosin in fission yeast
Toya, M., Motegi, F., Nakano, K., et al. (2001) · Genes to Cells · doi:10.1046/j.1365-2443.2001.00414.x · Cited by 42
“Members of the myosin I family are highly conserved among eukaryotes, and appear to play important roles in a number of cellular processes, such as endocytosis, membrane trafficking, contractility, and cell motility (Mooseker & Cheney 1995).”
Background
Deletion of the Myopathy Loop of Dictyostelium Myosin II and Its Impact on Motor Functions
Sasaki, N., Asukagawa, H., Yasuda, R., Hiratsuka, T., & Sutoh, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.53.37840 · Cited by 41
Hydrophobicity variations along the surface of the coiled-coil rod may mediate striated muscle myosin assembly in Caenorhabditis elegans.
Hoppe, P. E., & Waterston, R. (1996) · The Journal of Cell Biology · doi:10.1083/jcb.135.2.371 · Cited by 41
“In recent years, an increasingly diverse array of myosins have been identified that participate in a variety of cellular processes (for review see Mooseker and Cheney, 1995).”
Regulation and expression of metazoan unconventional myosins
Sokac, A. M., & Bement, W. M. (2000) · International review of cytology · doi:10.1016/s0074-7696(00)00005-x · Cited by 41
“The neck contains one or more ‘‘IQ’’ motifs, 23 amino acid repeats containing the sequence IQXXXRGXXXRK that are responsible for light-chain binding (Cheney and Mooseker, 1992).”
Background
Chromophore-assisted laser inactivation (CALI): probing protein functionin situ with a high degree of spatial and temporal resolution
Wang, F.-S., & Jay, D. G. (1996) · Trends in Cell Biology · doi:10.1016/s0962-8924(96)40005-8 · Cited by 40
Chemical-genetic inhibition of a sensitized mutant myosin Vb demonstrates a role in peripheral-pericentriolar membrane traffic
Provance, D. W., Gourley, C. R., Silan, C. M., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0305895101 · Cited by 40
To understand muscle you must take it apart
Batters, C., Veigel, C., Homsher, E. E., & Sellers, J. R. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00090 · Cited by 42
“In the 1990’s it became clear that there was a large superfamily of myosin molecules of which the classical skeletal and cardiac muscle myosins (now termed myosin II) was but one member (Mooseker and Cheney, 1995) (Figure 3).”
Background
Differential Expressions of Nuclear Proteomes between Honeybee (Apis mellifera L.) Queen and Worker Larvae: A Deep Insight into Caste Pathway Decisions
Begna, D., Han, B., Mao, F., et al. (2011) · Journal of Proteome Research · doi:10.1021/pr200974a · Cited by 39
Identification and Phylogenetic Analysis of Drosophila melanogaster Myosins
Tzolovsky, G., Millo, H., Pathirana, S., Wood, T., & Bownes, M. (2002) · Molecular Biology and Evolution · doi:10.1093/oxfordjournals.molbev.a004163 · Cited by 39
Versatile Formation of [2]Catenane and [2]Pseudorotaxane Structures; Threading and Noncovalent Stoppering by a Self-Assembled Macrocycle
Lim, C. W., Sakamoto, S., Yamaguchi, K., et al. (2004) · Organic Letters · doi:10.1021/ol036127l · Cited by 38
Drosophila Myosin VIIA Is a High Duty Ratio Motor with a Unique Kinetic Mechanism
Watanabe, S., Ikebe, R., & Ikebe, M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511592200 · Cited by 37
Unconventional Myosins, the Basis for Deafness in Mouse and Man
Hasson, T. (1997) · The American Journal of Human Genetics · doi:10.1086/514890 · Cited by 38
“Phylogenetic analysis of the motor domains has divided the family of myosins into 12 classes, 7 of which are present in vertebrates (Mooseker and Cheney 1995; Hasson and Mooseker 1996).”
Background
Myosin superfamily: The multi-functional and irreplaceable factors in spermatogenesis and testicular tumors
Li, Y.-R., & Yang, W. (2015) · Gene · doi:10.1016/j.gene.2015.10.022 · Cited by 37
Motor proteins of the eukaryotic cytoskeleton
Hoyt, M. A., Hyman, A. A., & Bähler, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.12747 · Cited by 37
Role of myosin 1H gene polymorphisms in mandibular retrognathism
Arun, R. M., Bhaskar, L. V., & Chitharanjan, A. B. (2016) · American Journal of Orthodontics and Dentofacial Orthopedics · doi:10.1016/j.ajodo.2015.10.028 · Cited by 36
The motor domain and the regulatory domain of myosin solely dictate enzymatic activity and phosphorylation-dependent regulation, respectively
Sata, M., Stafford, W. F., Mabuchi, K., & Ikebe, M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.1.91 · Cited by 36
Mother and Daughter Are Doing Fine: Asymmetric Cell Division in Yeast
Amon, A. (1996) · Cell · doi:10.1016/s0092-8674(00)81041-7 · Cited by 36
The Role of Unconventional Myosins in Dictyostelium Endocytosis
Titus, M. A. (2000) · Journal of Eukaryotic Microbiology · doi:10.1111/j.1550-7408.2000.tb00038.x · Cited by 36
A new potent antigen from Echinococcus granulosus associated with muscles and tegument
Fu, Y., Martinez, C., Chalar, C., et al. (1999) · Molecular and Biochemical Parasitology · doi:10.1016/s0166-6851(99)00084-5 · Cited by 35
Roles forDrosophila melanogasterMyosin IB in Maintenance of Enterocyte Brush-Border Structure and Resistance to the Bacterial PathogenPseudomonas entomophila
Hegan, P. S., Mermall, V., Tilney, L. G., et al. (2007) · Molecular Biology of the Cell · doi:10.1091/mbc.e07-02-0191 · Cited by 35
“It will be important in future studies to determine whether the Myo1B-associated light chains (presumably calmodulin) play a similar role to mouse Myo1a in contributing to cytosolic Ca2 homeostasis.”
BackgroundInfluentialSelf-citation

Authors: Mooseker, M. S., & Cheney, R. E.
Affiliations: Yale University (US)
ORCID: Cheney, Richard E.
Venue: Annual Review of Cell and Developmental Biology
Publisher: Annual Reviews
Published: 1995-11
Volume: 11
Issue: 1
Pages: 633-675
ISSN: 1081-0706 (ISSN-L)
1530-8995
DOI: 10.1146/annurev.cb.11.110195.003221
OpenAlex: W4234290082
Cited by: 370
References: 0
Citations by year: 2026: 1 · 2025: 2 · 2024: 1 · 2022: 3 · 2021: 5 · 2020: 2 · 2019: 4 · 2018: 1 · 2017: 5 · 2016: 7 · 2015: 5 · 2014: 4 · 2013: 3 · 2012: 10
FWCI: 38.87
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Cell and Developmental Biology (publishedVersion)
PubMed (publishedVersion)
Funders: National Institutes of Health (5p01dk038979-05)
National Institute of General Medical Sciences (GM25387)
National Institute of Diabetes and Digestive and Kidney Diseases (DK 38979, DK-34989, P30DK034989)
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiomyopathy and Myosin Studies
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Cellular Mechanics and Interactions
Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Microtubule and mitosis dynamics
Keywords: unconventional myosins, myosin superfamily, molecular motors, F-actin, ATP hydrolysis, myosin II, myosin structure, myosin function
MeSH terms: Acanthamoeba, Amino Acid Sequence, Animals, Deafness, Drosophila, Humans, Molecular Sequence Data, Myosins, Phylogeny, Saccharomyces cerevisiae, Swine, Arabidopsis, Sequence Homology, Amino Acid, Mice

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Unconventional Myosins

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cited by

Related

Metadata

Record

About these checks