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Cited by 256

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

THE TIGHT JUNCTION: Morphology to Molecules

Stevenson, Bruce R., Keon, Brigitte H.·1998·Annual Review of Cell and Developmental Biology

Abstract

▪ Abstract The tight junction forms a regulated barrier in the paracellular pathway between epithelial and endothelial cells. This intercellular junction also demarcates the compositionally distinct apical and basolateral membranes. While the existence of a paracellular barrier in epithelia was hypothesized by physiologists over a century ago, the molecular characterization of the tight junction is a relatively new and rapidly expanding area of research. It is now recognized that the tight junction is comprised of at least nine peripheral and one integral membrane proteins. This complex includes members of a protein family related to tumor suppression and signal transduction, a rab protein, and a Ras target protein. The characteristics of, interactions between, and potential physiological roles of these proteins at the tight junction are discussed.

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Crossref · 10.1146/annurev.cellbio.14.1.89

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Metadata

Authors
Stevenson, B. R., & Keon, B. H.
Venue
Annual Review of Cell and Developmental Biology
Published
1998-11
Volume
14
Issue
1
Pages
89-109
ISSN
  • 1081-0706 (ISSN-L)
  • 1530-8995
OpenAlex
W2143776806
Cited by
256
References
3
FWCI
1.75
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: THE TIGHT JUNCTION: Morphology to Molecules. https://app.cochat.ai/papers/10.1146/annurev.cellbio.14.1.89
The paper
Stevenson, B. R., & Keon, B. H. (1998). THE TIGHT JUNCTION: Morphology to Molecules. Annual Review of Cell and Developmental Biology. https://doi.org/10.1146/annurev.cellbio.14.1.89

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.