The DOI matches its Crossref record.
Host Immunity to Ticks
Abstract
The tick-host-pathogen interface is characterized by complex immunological interactions. Tick feeding induces host immune regulatory and effector pathways involving antibodies, complement, antigen-presenting cells, T lymphocytes, and other bioactive molecules. Acquired resistance impairs tick engorgement, ova production, and viability. Tick countermeasures to host defenses reduce T-lymphocyte proliferation, elaboration of the T H 1 cytokines interleukin-2 and interferon-γ, production of macrophage cytokines interleukin-1 and tumor necrosis factor, and antibody responses. The dynamic balance between acquired resistance and tick modulation of host immunity affects engorgement and pathogen transmission. A thorough understanding of acquired immunity to ticks is essential for rational development of antitick vaccines.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Commins, S. P., James, H. R., Kelly, L. A., Pochan, S. L., Workman, L. J., Perzanowski, M. S., Kocan, K. M., Fahy, J. V., Nganga, L. W., Ronmark, E., et al. (2011) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2011.02.019 · Cited by 642
Exploring the sialome of the tick Ixodes scapularis
Valenzuela, J. G., Francischetti, I. M. B., Pham, V. M., Garfield, M. K., Mather, T. N., & Ribeiro, J. M. C. (2002) · Journal of Experimental Biology · doi:10.1242/jeb.205.18.2843 · Cited by 299
Wada, T., Ishiwata, K., Koseki, H., Ishikura, T., Ugajin, T., Ohnuma, N., Obata, K., Ishikawa, R., Yoshikawa, S., Mukai, K., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci42680 · Cited by 294
Nonredundant Roles of Basophils in Immunity
Karasuyama, H., Mukai, K., Obata, K., Tsujimura, Y., & Wada, T. (2011) · Annual Review of Immunology · doi:10.1146/annurev-immunol-031210-101257 · Cited by 211
Kongsuwan, K., Josh, P., Colgrave, M. L., Bagnall, N. H., Gough, J., Burns, B., & Pearson, R. (2010) · International Journal for Parasitology · doi:10.1016/j.ijpara.2009.10.013 · Cited by 48
Metadata
- Authors
- Wikel, S. K.
- Venue
- Annual Review of Entomology
- Publisher
- Annual Reviews
- Published
- 1996-01
- Volume
- 41
- Issue
- 1
- Pages
- 1-22
- ISSN
- 0066-4170 (ISSN-L)
- 1545-4487
- OpenAlex
- W2131164989
- Cited by
- 352
- References
- 0
- FWCI
- 12.40
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Host Immunity to Ticks. https://app.cochat.ai/papers/10.1146/annurev.en.41.010196.000245
- The paper
- Wikel, S. K. (1996). Host Immunity to Ticks. Annual Review of Entomology. https://doi.org/10.1146/annurev.en.41.010196.000245
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
